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Ten simple rules for training scientists to make better software Journal article
Gallagher, Kit, Creswell, Richard, Lambert, Ben, Robinson, Martin, Lei, Chon Lok, Mirams, Gary R., Gavaghan, David J.. Ten simple rules for training scientists to make better software[J]. PLOS COMPUTATIONAL BIOLOGY, 2024, 20(9), e1012410.
Authors:  Gallagher, Kit;  Creswell, Richard;  Lambert, Ben;  Robinson, Martin;  Lei, Chon Lok; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:3.8/4.3 | Submit date：2024/10/10
The impact of uncertainty in hERG binding mechanism on in silico predictions of drug-induced proarrhythmic risk Journal article
Lei, Chon Lok, Whittaker, Dominic G., Mirams, Gary R.. The impact of uncertainty in hERG binding mechanism on in silico predictions of drug-induced proarrhythmic risk[J]. British Journal of Pharmacology, 2024, 181(7), 987-1004.
Authors:  Lei, Chon Lok;  Whittaker, Dominic G.;  Mirams, Gary R.
Favorite | TC[WOS]:2 TC[Scopus]:1  IF:6.8/7.4 | Submit date：2024/02/22
Binding Mechanism  Cipa  Herg  Mathematical Modelling  Proarrhythmic Risk  Safety Pharmacology  Torsade  
Understanding the impact of numerical solvers on inference for differential equation models Journal article
Creswell, Richard, Shepherd, Katherine M., Lambert, Ben, Mirams, Gary R., Lei, Chon Lok, Tavener, Simon, Robinson, Martin, Gavaghan, David J.. Understanding the impact of numerical solvers on inference for differential equation models[J]. Journal of the Royal Society Interface, 2024, 21(212), 20230369.
Authors:  Creswell, Richard;  Shepherd, Katherine M.;  Lambert, Ben;  Mirams, Gary R.;  Lei, Chon Lok; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:3.7/4.0 | Submit date：2024/04/02
Bayesian Statistics  Compartmental Models  Hydrological Modelling  Inference  Ordinary Differential Equations  Truncation Error  
Empirical Quantification of Predictive Uncertainty Due to Model Discrepancy by Training with an Ensemble of Experimental Designs: An Application to Ion Channel Kinetics Journal article
Shuttleworth, Joseph G., Lei, Chon Lok, Whittaker, Dominic G., Windley, Monique J., Hill, Adam P., Preston, Simon P., Mirams, Gary R.. Empirical Quantification of Predictive Uncertainty Due to Model Discrepancy by Training with an Ensemble of Experimental Designs: An Application to Ion Channel Kinetics[J]. Bulletin of Mathematical Biology, 2024, 86(1), 2.
Authors:  Shuttleworth, Joseph G.;  Lei, Chon Lok;  Whittaker, Dominic G.;  Windley, Monique J.;  Hill, Adam P.; et al.
Favorite | TC[WOS]:2 TC[Scopus]:4  IF:2.0/2.1 | Submit date：2024/02/22
Discrepancy  Experimental Design  Ion Channel  Mathematical Model  Misspecification  Uncertainty Quantification  
Model-driven optimal experimental design for calibrating cardiac electrophysiology models Journal article
Lei,Chon Lok, Clerx,Michael, Gavaghan,David J., Mirams,Gary R.. Model-driven optimal experimental design for calibrating cardiac electrophysiology models[J]. Computer Methods and Programs in Biomedicine, 2023, 240, 107690.
Authors:  Lei,Chon Lok;  Clerx,Michael;  Gavaghan,David J.;  Mirams,Gary R.
Favorite | TC[WOS]:5 TC[Scopus]:5  IF:4.9/5.5 | Submit date：2023/08/03
Action Potential  Electrophysiology  Mathematical Modelling  Model Calibration  Optimal Experimental Design  Patch Clamp  
Using many different voltage protocols to characterise discrepancy in mathematical ion channel models Journal article
Shuttleworth, Joseph G., Lok Lei, Chon, Windley, Monique, Hill, Adam P., Perry, Matthew D., Preston, Simon, Mirams, Gary R.. Using many different voltage protocols to characterise discrepancy in mathematical ion channel models[J]. Biophysical journal, 2023, 122(3S1), 242a.
Authors:  Shuttleworth, Joseph G.;  Lok Lei, Chon;  Windley, Monique;  Hill, Adam P.;  Perry, Matthew D.; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0 | Submit date：2023/03/06
A nonlinear and time-dependent leak current in the presence of calcium fluoride patch-clamp seal enhancer Journal article
Lei, Chon Lok, Fabbri, Alan, Whittaker, Dominic G., Clerx, Michael, Windley, Monique J., Hill, Adam P., Mirams, Gary R., de Boer, Teun P.. A nonlinear and time-dependent leak current in the presence of calcium fluoride patch-clamp seal enhancer[J]. Wellcome Open Research, 2021, 5, 152.
Authors:  Lei, Chon Lok;  Fabbri, Alan;  Whittaker, Dominic G.;  Clerx, Michael;  Windley, Monique J.; et al.
Favorite | TC[Scopus]:5 | Submit date：2021/11/30
Automated Patch  Electrophysiology  Leak Current  Patch Clamp  Seal Enhancer  
Neural Network Differential Equations For Ion Channel Modelling Journal article
Lei, Chon Lok, Mirams, Gary R.. Neural Network Differential Equations For Ion Channel Modelling[J]. Frontiers in Physiology, 2021, 12, 708944.
Authors:  Lei, Chon Lok;  Mirams, Gary R.
Favorite | TC[WOS]:5 TC[Scopus]:4  IF:3.2/4.0 | Submit date：2021/11/30
Differential Equations  Electrophysiology  Human Ether-à-go-go-related Gene  Ion Channels  Mathematical Modelling  Model Discrepancy  Neural Networks  Neural Odes