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A natural small molecule aspidosperma-type alkaloid, hecubine, as a new TREM2 activator for alleviating lipopolysaccharide-induced neuroinflammation in vitro and in vivo Journal article
Li, Lin, He, Yu Lin, Xu, Nan, Wang, Xiu Fen, Song, Bing, Tang, Ben Qin, Lee, Simon Ming Yuen. A natural small molecule aspidosperma-type alkaloid, hecubine, as a new TREM2 activator for alleviating lipopolysaccharide-induced neuroinflammation in vitro and in vivo[J]. Redox Biology, 2024, 70, 103057.
Authors:  Li, Lin;  He, Yu Lin;  Xu, Nan;  Wang, Xiu Fen;  Song, Bing; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:10.7/11.7 | Submit date：2024/05/02
Anti-neuroinflammation  Anti-oxidation  Aspidosperma-type Alkaloids  Hecubine  Microglia  Trem2  
A novel oxoisoaporphine-type alkaloid from the rhizome of Menispermum dauricum Other
2023-01-02
Authors:  Ren, Wen Jing;  Zhu, Guo Yuan;  Ma, Yan;  Cao, Yan Hua;  Duan, Bao Guo; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1 | Submit date：2023/01/30
Alkaloids  Aporphine-type  Cytotoxicity  Menispermaceae  Menispermum Dauricum  Oxoisoaporphine-type  
2D NMR-based MatchNat Dereplication Strategy Enables Explosive Discovery of Novel Diterpenoid Alkaloids† Journal article
Yin, Tian Peng, Yu, Yi, Liu, Qing Hua, Zhou, Ming Yue, Zhu, Guo Yuan, Bai, Li Ping, Zhang, Wei, Jiang, Zhi Hong. 2D NMR-based MatchNat Dereplication Strategy Enables Explosive Discovery of Novel Diterpenoid Alkaloids†[J]. Chinese Journal of Chemistry, 2022, 40(18), 2169-2178.
Authors:  Yin, Tian Peng;  Yu, Yi;  Liu, Qing Hua;  Zhou, Ming Yue;  Zhu, Guo Yuan; et al.
Favorite | TC[WOS]:6 TC[Scopus]:5  IF:5.5/5.2 | Submit date：2023/01/30
Aconitum  Alkaloids  Dereplication  Natural products  NMR spectroscopy  
β-Carboline Alkaloids From the Deep-Sea Fungus Trichoderma sp. MCCC 3A01244 as a New Type of Anti-pulmonary Fibrosis Agent That Inhibits TGF-β/Smad Signaling Pathway Journal article
Hao, Meng Jiao, Chen, Pei Nan, Li, Hou Jin, Wu, Feng, Zhang, Guang Yu, Shao, Zong Ze, Liu, Xiu Pian, Ma, Wen Zhe, Xu, Jun, Mahmud, Taifo, Lan, Wen Jian. β-Carboline Alkaloids From the Deep-Sea Fungus Trichoderma sp. MCCC 3A01244 as a New Type of Anti-pulmonary Fibrosis Agent That Inhibits TGF-β/Smad Signaling Pathway[J]. Frontiers in Microbiology, 2022, 13.
Authors:  Hao, Meng Jiao;  Chen, Pei Nan;  Li, Hou Jin;  Wu, Feng;  Zhang, Guang Yu; et al.
Favorite | TC[WOS]:14 TC[Scopus]:17  IF:4.0/5.1 | Submit date：2023/01/30
Acid-directed Strategy  Anti-pulmonary Fibrosis  Tgf-β/smad  Trichoderma  Β-carboline Alkaloids  
New iboga-type alkaloids from Ervatamia officinalis and their anti-inflammatory activity Journal article
Tang, Ben qin, Li, Zi wei, Li, Lin, Li, Bao jing, Bian, Ya qi, Yu, Guo dong, Chang, Yu, Lee, Simon Ming yuen, Zhang, Xiao qi. New iboga-type alkaloids from Ervatamia officinalis and their anti-inflammatory activity[J]. Fitoterapia, 2022, 156, 105085.
Authors:  Tang, Ben qin;  Li, Zi wei;  Li, Lin;  Li, Bao jing;  Bian, Ya qi; et al.
Favorite | TC[WOS]:3 TC[Scopus]:4  IF:2.5/2.7 | Submit date：2022/02/21
Anti-inflammatory  Ervatamia Officinalis  Ervaoffines  Iboga-type Alkaloids  No Release  
Chemical characterization of flavonoids and alkaloids in safflower ( Carthamus tinctorius L.) by comprehensive two-dimensional hydrophilic interaction chromatography coupled with hybrid linear ion trap Orbitrap mass spectrometry Journal article
Wang, Songsong, Cao, Jiliang, Deng, Jiagang, Hou, Xiaotao, Hao, Erwei, Zhang, Lei, Yu, Hua, Li, Peng. Chemical characterization of flavonoids and alkaloids in safflower ( Carthamus tinctorius L.) by comprehensive two-dimensional hydrophilic interaction chromatography coupled with hybrid linear ion trap Orbitrap mass spectrometry[J]. Food Chemistry-X, 2021, 12, 100143.
Authors:  Wang, Songsong;  Cao, Jiliang;  Deng, Jiagang;  Hou, Xiaotao;  Hao, Erwei; et al.
Favorite | TC[WOS]:12 TC[Scopus]:12  IF:6.5/6.4 | Submit date：2022/08/29
Alkaloids  Carthamus Tinctorius l  Flavonoids  Ltq-orbitrap Mass Spectrometry  Online Hilic×hilic  
Chemical characterization of flavonoids and alkaloids in safflower (Carthamus tinctorius L.) by comprehensive two-dimensional hydrophilic interaction chromatography coupled with hybrid linear ion trap Orbitrap mass spectrometry Journal article
Wang, Songsong, Cao, Jiliang, Deng, Jiagang, Hou, Xiaotao, Hao, Erwei, Zhang, Lei, Yu, Hua, Li, Peng. Chemical characterization of flavonoids and alkaloids in safflower (Carthamus tinctorius L.) by comprehensive two-dimensional hydrophilic interaction chromatography coupled with hybrid linear ion trap Orbitrap mass spectrometry[J]. Food Chemistry-X, 2021, 12, 100143.
Authors:  Wang, Songsong;  Cao, Jiliang;  Deng, Jiagang;  Hou, Xiaotao;  Hao, Erwei; et al.
Favorite | TC[WOS]:12 TC[Scopus]:12  IF:6.5/6.4 | Submit date：2022/05/11
Alkaloids  Carthamus Tinctorius l  Flavonoids  Ltq-orbitrap Mass Spectrometry  Online Hilic×hilic  
Alkaloids in Diet Book chapter
出自: Handbook of Dietary Phytochemicals, Singapore:Springer Singapore, 2019, 页码:1-35
Authors:  Chen, C.;  Lin, L.
Favorite |  | Submit date：2022/07/27
Alkaloids  Bioactive constituents  Toxicity  Bioavailability  Safety  
Lycodine-type alkaloids from Lycopodiastrum casuarinoides and their acetylcholinesterase inhibitory activity Journal article
Feng,Zheling, Chen,Shixin, Wang,Wei, Feng,Lu, Dong,Yanyan, Zou,Yiping, Ke,Changqiang, Tang,Chunping, Yao,Sheng, Zhang,Haiyan, Gan,Lishe, Ye,Yang, Lin,Ligen. Lycodine-type alkaloids from Lycopodiastrum casuarinoides and their acetylcholinesterase inhibitory activity[J]. Fitoterapia, 2019, 139, 104378.
Authors:  Feng,Zheling;  Chen,Shixin;  Wang,Wei;  Feng,Lu;  Dong,Yanyan; et al.
Favorite | TC[WOS]:8 TC[Scopus]:9  IF:2.5/2.7 | Submit date：2021/03/01
Ecd  Lycodine-type Alkaloids  Lycopodiaceae  Lycopodiastrum Casuarinoides  Td-dft  
A Concise Total Synthesis of (−)-Himalensine A Journal article
Chen, Yuye, Hu, Jingping, Guo, Lian Dong, Zhong, Weihe, Ning, Chengqing, Xu, Jing. A Concise Total Synthesis of (−)-Himalensine A[J]. Angewandte Chemie - International Edition, 2019, 58(22), 7390-7394.
Authors:  Chen, Yuye;  Hu, Jingping;  Guo, Lian Dong;  Zhong, Weihe;  Ning, Chengqing; et al.
Favorite | TC[WOS]:53 TC[Scopus]:54  IF:16.1/16.2 | Submit date：2022/04/15
Coupling Reaction  Daphniphyllum Alkaloids  Natural Products  Selective Amide Reduction  Total Synthesis