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Alkaloids in Diet
Chen, C.; Lin, L.
2019-12-12
Source PublicationHandbook of Dietary Phytochemicals
Publication PlaceSingapore
PublisherSpringer Singapore
Pages1-35
AbstractFood is one of the three basic requirements of mankind, supplying six kinds of nutrients including water, carbohydrate, protein, lipid, vitamins and minerals. Alkaloid-containing foods are an intrinsic part of the human diet, such like tea, coffee and tomato. These food oriented alkaloid constituents possess diverse effects on human body, either wanted or unwanted. A large variety of food-produced alkaloids exhibit potent bioactivities, such as caffeine, atropine and cocaine. Whereas, lots of other alkaloids are toxic to human, such as pyrrolizidine alkaoids. This chapter focuses on the alkaloids in human diet, their mode of action and possible toxic effects. To organize this chapter, the alkaloids were categrized into nine groups based on their structures: pyrrolizidine alkaloids, tropane alkaloids, quinolizidine alkaloids, isoquinoline alkaloids, quinoline alkaloids, glycoalkaloids, purine alkaloids, pyridine alkaloids, and amide alkaloids. The structures of food-derived alkaloids are descried, and their pharmacological activities, bioavailability, metabolism, and toxicological effects are discussed. Moreover, the application of alkaloids in medicines and food supplement, patents, as well as a conclusion about their current impact on food safety are reviewed. The main purpose of this chapter is to provide a comprehensive and up-to-date state of knowledge from phytochemical, pharmacological, and toxicological studies performed on alkaloids in human food.
KeywordAlkaloids Bioactive constituents Toxicity Bioavailability Safety
URLView the original
Language英語English
ISBN9789811317453
The Source to ArticlePB_Publication
PUB ID49984
Document TypeBook chapter
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorLin, L.
Recommended Citation
GB/T 7714
Chen, C.,Lin, L.. Alkaloids in Diet[M]. Handbook of Dietary Phytochemicals, Singapore:Springer Singapore, 2019, 1-35.
APA Chen, C.., & Lin, L. (2019). Alkaloids in Diet. Handbook of Dietary Phytochemicals, 1-35.
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