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Selective detection of mitochondrial Cu2+ in living cells by a near-infrared iridium(III) complex Journal article
Du, Jianxiong, Wu, Lei, Hu, Fahui, Liu, Jin Biao, Leung, Chung Hang, Wang, Wanhe. Selective detection of mitochondrial Cu2+ in living cells by a near-infrared iridium(III) complex[J]. Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2025, 330, 125637.
Authors:  Du, Jianxiong;  Wu, Lei;  Hu, Fahui;  Liu, Jin Biao;  Leung, Chung Hang; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.3/3.8 | Submit date：2025/01/22
Mitochondrial Cu2++  Near-infrared  Iridium(Iii) Complex  Imaging  Luminescent Probe  
Microfluidic detection using G-quadruplex DNA-based biosensors Journal article
Wu, Jia, Li, Yujie, Wang, Lijun, Nao, Sang Cuo, Shiu-Hin Chan, Daniel, Wong, Chun Yuen, Yang, Guanjun, Wang, Wanhe, Leung, Chung Hang. Microfluidic detection using G-quadruplex DNA-based biosensors[J]. TrAC - Trends in Analytical Chemistry, 2025, 184.
Authors:  Wu, Jia;  Li, Yujie;  Wang, Lijun;  Nao, Sang Cuo;  Shiu-Hin Chan, Daniel; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:11.8/12.7 | Submit date：2025/01/22
G-quadruplex  Microfluidics  Biosensors  Ligand  Biomarker  Drug Screening  
KDM5 family as therapeutic targets in breast cancer: Pathogenesis and therapeutic opportunities and challenges Review article
2024
Authors:  Li, Chang Yun;  Wang, Wanhe;  Leung, Chung Hang;  Yang, Guan Jun;  Chen, Jiong
Favorite | TC[WOS]:5 TC[Scopus]:7  IF:27.7/31.3 | Submit date：2024/06/05
Breast Cancer  Histone Demethylation  Kdm5  Kdm5 Inhibitors  Therapeutic Target  
An iridium(III) complex-based luminogenic probe for high-throughput screening of hydrogen sulfide donors in living cells Journal article
Wu, Ke Jia, Sun, Wen, Sun, Jian Min, Lu, Chang, Sun, Ning, Leung, Chung‐Hang, Li, Yan, Wu, Chun. An iridium(III) complex-based luminogenic probe for high-throughput screening of hydrogen sulfide donors in living cells[J]. Communications Chemistry, 2024, 7(1), 263.
Authors:  Wu, Ke Jia;  Sun, Wen;  Sun, Jian Min;  Lu, Chang;  Sun, Ning; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:5.9/6.3 | Submit date：2024/12/05
A NIR iridium(III) complex-based luminescence probe for imaging mitochondria pyruvate dehydrogenase kinase 1 in triple-negative breast cancer cells Journal article
Jing, Shaozhen, Song, Ying Qi, Liu, Jingqi, Zhao, Chen, Wang, Ling, Chan, Daniel Shiu Hin, Wong, Chun Yuen, Lee, Simon Ming Yuen, Wang, Jing, Leung, Chung Hang, Wang, Wanhe. A NIR iridium(III) complex-based luminescence probe for imaging mitochondria pyruvate dehydrogenase kinase 1 in triple-negative breast cancer cells[J]. Sensors and Actuators B: Chemical, 2024, 418, 136265.
Authors:  Jing, Shaozhen;  Song, Ying Qi;  Liu, Jingqi;  Zhao, Chen;  Wang, Ling; et al.
Favorite | TC[WOS]:0 TC[Scopus]:1  IF:8.0/7.0 | Submit date：2024/08/05
Breast Cancer  Dichloroacetic Acid (Dca)  Iridium(Iii) Complex  Mitochondrial Targeting  Nir Imaging  Pyruvate Dehydrogenase Kinase 1 (Pdk1)  
Tailoring obeticholic acid activity by iridium(III) complex conjugation to develop a farnesoid X receptor probe Journal article
Niu, Dou, Wu, Xiaolei, Zhang, Yuxin, Wang, Xueliang, Shiu-Hin Chan, Daniel, Jing, Shaozhen, Wong, Chun Yuen, Wang, Wanhe, Leung, Chung Hang. Tailoring obeticholic acid activity by iridium(III) complex conjugation to develop a farnesoid X receptor probe[J]. Journal of Advanced Research, 2024.
Authors:  Niu, Dou;  Wu, Xiaolei;  Zhang, Yuxin;  Wang, Xueliang;  Shiu-Hin Chan, Daniel; et al.
Favorite | TC[Scopus]:0  IF:11.4/11.0 | Submit date：2024/12/05
Iridium Complex  Fxr  Nuclear Receptor  Tailoring Activity  Imaging Probe  
Visualizing cellular uptake of metformin by a luminogenic bioimaging probe in living cancer cells Journal article
Wang, Xueliang, Jing, Shaozhen, Leung, Chung Hang, Wang, Wanhe, Wang, Jing. Visualizing cellular uptake of metformin by a luminogenic bioimaging probe in living cancer cells[J]. Microchemical Journal, 2024, 205, 111225.
Authors:  Wang, Xueliang;  Jing, Shaozhen;  Leung, Chung Hang;  Wang, Wanhe;  Wang, Jing
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.9/4.5 | Submit date：2024/08/05
Bioimaging  Iridium(Iii) Complex  Living Cells  Luminescent Probe  Metformin  
The enhancing effects of selenomethionine on harmine in attenuating pathological cardiac hypertrophy via glycolysis metabolism Journal article
Chen, Qi, Wang, Wen Yan, Xu, Qing Yang, Dai, Yan Fa, Zhu, Xing Yu, Chen, Zhao Yang, Sun, Ning, Leung, Chung Hang, Gao, Fei, Wu, Ke Jia. The enhancing effects of selenomethionine on harmine in attenuating pathological cardiac hypertrophy via glycolysis metabolism[J]. Journal of Cellular and Molecular Medicine, 2024, 28(19), e70124.
Authors:  Chen, Qi;  Wang, Wen Yan;  Xu, Qing Yang;  Dai, Yan Fa;  Zhu, Xing Yu; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.3/5.0 | Submit date：2024/10/10
Cardiac Hypertrophy  Combination Therapy  Glycolysis Metabolism  Harmine  Selenomethionine  
Probing the AFF4–CCNT1 protein–protein interaction using a metal–organic conjugate for treating triple-negative breast cancer Journal article
Song, Ying Qi, Xu, Yiwen, Yang, Li Jun, Wang, Ling, Jing, Shaozhen, Yang, Guan Jun, Shiu-Hin Chan, Daniel, Wong, Chun Yuen, Wang, Wanhe, Kam Wai Wong, Vincent, Leung, Chung Hang. Probing the AFF4–CCNT1 protein–protein interaction using a metal–organic conjugate for treating triple-negative breast cancer[J]. Chemical Engineering Journal, 2024, 496, 153685.
Authors:  Song, Ying Qi;  Xu, Yiwen;  Yang, Li Jun;  Wang, Ling;  Jing, Shaozhen; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:13.3/13.2 | Submit date：2024/08/05
Aff4  Ccnt1  Metal–organic Conjugate  Protein–protein Interaction  Triple-negative Breast Cancer  
Iridium/Rhodium-based complexes for protein targeted drug discovery, 中國化學會第十七屆生物無機化學會議暨金屬化學生物學學術會議 Presentation
会议地点: Wuhan, China, 会议日期: 24-08-2024, 报告日期: 2024-08-01
Authors:  LEUNG CHUNG HANG
Favorite |  | Submit date：2024/08/30