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Combined inhibition of pyruvate dehydrogenase kinase 1 and lactate dehydrogenase a induces metabolic and signaling reprogramming and enhances lung adenocarcinoma cell killing Journal article
Zhou, Yan, Guo, Yizhen, Ran, Maoxin, Shan, Wenying, Granchi, Carlotta, Giovannetti, Elisa, Minutolo, Filippo, Peters, Godefridus J., Tam, Kin Yip. Combined inhibition of pyruvate dehydrogenase kinase 1 and lactate dehydrogenase a induces metabolic and signaling reprogramming and enhances lung adenocarcinoma cell killing[J]. Cancer Letters, 2023, 577, 216425.
Authors:  Zhou, Yan;  Guo, Yizhen;  Ran, Maoxin;  Shan, Wenying;  Granchi, Carlotta; et al.
Favorite | TC[WOS]:9 TC[Scopus]:7  IF:9.1/8.3 | Submit date：2023/12/04
Anticancer  Combination Treatment  Non-small Cell Lung Cancer  Warburg Effect  
Lycorine promotes IDH1 acetylation to induce mitochondrial dynamics imbalance in colorectal cancer cells Journal article
Fang-Fang Zhuo, Ling Li, Ting-Ting Liu, Xiao-Min Liang, Zhuo Yang, Yong-Zhe Zheng, Qian-Wei Luo, Jia-Hong Lu, Dan Liu, Ke-Wu Zeng, Peng-Fei Tu. Lycorine promotes IDH1 acetylation to induce mitochondrial dynamics imbalance in colorectal cancer cells[J]. Cancer Letters, 2023, 573, 216364.
Authors:  Fang-Fang Zhuo;  Ling Li;  Ting-Ting Liu;  Xiao-Min Liang;  Zhuo Yang; et al.
Favorite | TC[WOS]:7 TC[Scopus]:9  IF:9.1/8.3 | Submit date：2023/09/22
Colorectal Cancer  Isocitrate Dehydrogenase (Idh)  Lycorine  Mitochondrial Dynamics  Oxidative Stress  Sirtuin 1  
Reprogramming of TAMs via the STAT3/CD47-SIRPα axis promotes acquired resistance to EGFR-TKIs in lung cancer Journal article
Lu, Jiaye, Li, Jingwei, Lin, Ziyou, Li, Huaxuan, Lou, Linlin, Ding, Wen, Ouyang, Shumin, Wu, Yonghui, Wen, Yuanzhen, Chen, Xiaobing, Yue, Peibin, Wang, Yuanxiang, Liu, Peiqing, Lu, Jinjian, Zhang, Jian, Feng, Weineng, Zhang, Xiaolei. Reprogramming of TAMs via the STAT3/CD47-SIRPα axis promotes acquired resistance to EGFR-TKIs in lung cancer[J]. Cancer Letters, 2023, 564, 216205.
Authors:  Lu, Jiaye;  Li, Jingwei;  Lin, Ziyou;  Li, Huaxuan;  Lou, Linlin; et al.
Favorite | TC[WOS]:25 TC[Scopus]:25  IF:9.1/8.3 | Submit date：2023/07/20
Acquired Tki Resistance  Cd47  Lung Cancer  Stat3  Tams  
Acetyltanshinone IIA is more potent than lapatinib in inhibiting cell growth and degrading HER2 protein in drug-resistant HER2-positive breast cancer cells Journal article
Huang, Bin, Yip,Wai Kien, Wei, Na, Luo, Kathy Qian. Acetyltanshinone IIA is more potent than lapatinib in inhibiting cell growth and degrading HER2 protein in drug-resistant HER2-positive breast cancer cells[J]. Cancer Letters, 2020, 490, 1-11.
Authors:  Huang, Bin;  Yip,Wai Kien;  Wei, Na;  Luo, Kathy Qian
Favorite | TC[WOS]:8 TC[Scopus]:8  IF:9.1/8.3 | Submit date：2021/03/02
Acetyltanshinone Iia  Drug Resistance  Her2 Degradation  Her2-positive Breast Cancer  
Acetyltanshinone IIA is more potent than lapatinib in inhibiting cell growth and degrading HER2 protein in drug-resistant HER2-positive breast cancer cells Journal article
Huang, B, Yip, WK, Na, W, Luo, KQ. Acetyltanshinone IIA is more potent than lapatinib in inhibiting cell growth and degrading HER2 protein in drug-resistant HER2-positive breast cancer cells[J]. Cancer Letters, 2020, 1-11.
Authors:  Huang, B;  Yip, WK;  Na, W;  Luo, KQ
Favorite |   IF:9.1/8.3 | Submit date：2022/08/26
Acetyltanshinone IIA  drug resistance  HER2-positive breast cancer  HER2 degradation  
Artificial intelligence in cancer diagnosis and prognosis: Opportunities and challenges Journal article
Huang, S, Yang, J, Fong, S., Zhao, Q.. Artificial intelligence in cancer diagnosis and prognosis: Opportunities and challenges[J]. Cancer Letters, 2020, 61-67.
Authors:  Huang, S;  Yang, J;  Fong, S.;  Zhao, Q.
Favorite |   IF:9.1/8.3 | Submit date：2023/08/25
Cancer diagnosis  Deep learning  Deep neural network  Machine learning  Prognosis prediction  
Artificial intelligence in cancer diagnosis and prognosis: Opportunities and challenges Journal article
Shigao Huang, Jie Yang, Simon Fong, Qi Zhao. Artificial intelligence in cancer diagnosis and prognosis: Opportunities and challenges[J]. Cancer Letters, 2019, 471, 61-71.
Authors:  Shigao Huang;  Jie Yang;  Simon Fong;  Qi Zhao
Favorite | TC[WOS]:279 TC[Scopus]:355  IF:9.1/8.3 | Submit date：2021/03/04
Cancer Diagnosis  Prognosis Prediction  Deep Learning  Machine Learning  Deep Neural Network  
PTEN deficiency confers colorectal cancer cell resistance to dual inhibitors of FLT3 and aurora kinase A Journal article
Yifan Liu, Eun Ju Yang, Baoyuan Zhang, Zhengqiang Miao, Changjie Wu, Junfang Lyu, Kaeling Tan, Terence Chuen Wai Poon, Joong Sup Shim. PTEN deficiency confers colorectal cancer cell resistance to dual inhibitors of FLT3 and aurora kinase A[J]. CANCER LETTERS, 2018, 436, 28-37.
Authors:  ; et al.
Favorite | TC[WOS]:13 TC[Scopus]:11  IF:9.1/8.3 | Submit date：2018/10/30
Akt  Kw2449  Synthetic Lethality  Aurka  Drug Combination  
Osimertinib resistance in non-small cell lung cancer: Mechanisms and therapeutic strategies Journal article
Tang, Zheng-Hai, Lu, Jin-Jian. Osimertinib resistance in non-small cell lung cancer: Mechanisms and therapeutic strategies[J]. CANCER LETTERS, 2018, 420, 242-246.
Authors:  Tang, Zheng-Hai;  Lu, Jin-Jian
Favorite | TC[WOS]:100 TC[Scopus]:109  IF:9.1/8.3 | Submit date：2018/10/30
Osimertinib  Azd9291  Egfr Tki  Resistant Mechanisms  Therapeutic Strategies  
Identification of a novel autophagic inhibitor cepharanthine to enhance the anti-cancer property of dacomitinib in non-small cell lung cancer Journal article
Tang, Zheng-Hai, Cao, Wen-Xiang, Guo, Xia, Dai, Xiao-Yang, Lu, Jia-Hong, Chen, Xiuping, Zhu, Hong, Lu, Jin-Jian. Identification of a novel autophagic inhibitor cepharanthine to enhance the anti-cancer property of dacomitinib in non-small cell lung cancer[J]. CANCER LETTERS, 2018, 412, 1-9.
Authors:  Tang, Zheng-Hai;  Cao, Wen-Xiang;  Guo, Xia;  Dai, Xiao-Yang;  Lu, Jia-Hong; et al.
Favorite | TC[WOS]:36 TC[Scopus]:38  IF:9.1/8.3 | Submit date：2018/10/30
Cepharanthine  Autophagy  Lysosome  Dacomitinib  Nsclc