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Artificial intelligence in cancer diagnosis and prognosis: Opportunities and challenges
Shigao Huang1; Jie Yang2,3; Simon Fong2,4; Qi Zhao1
2019-12-10
Source PublicationCancer Letters
ISSN0304-3835
Volume471Pages:61-71
Abstract

Cancer is an aggressive disease with a low median survival rate. Ironically, the treatment process is long and very costly due to its high recurrence and mortality rates. Accurate early diagnosis and prognosis prediction of cancer are essential to enhance the patient's survival rate. Developments in statistics and computer engineering over the years have encouraged many scientists to apply computational methods such as multivariate statistical analysis to analyze the prognosis of the disease, and the accuracy of such analyses is significantly higher than that of empirical predictions. Furthermore, as artificial intelligence (AI), especially machine learning and deep learning, has found popular applications in clinical cancer research in recent years, cancer prediction performance has reached new heights. This article reviews the literature on the application of AI to cancer diagnosis and prognosis, and summarizes its advantages. We explore how AI assists cancer diagnosis and prognosis, specifically with regard to its unprecedented accuracy, which is even higher than that of general statistical applications in oncology. We also demonstrate ways in which these methods are advancing the field. Finally, opportunities and challenges in the clinical implementation of AI are discussed. Hence, this article provides a new perspective on how AI technology can help improve cancer diagnosis and prognosis, and continue improving human health in the future.

KeywordCancer Diagnosis Prognosis Prediction Deep Learning Machine Learning Deep Neural Network
DOI10.1016/j.canlet.2019.12.007
URLView the original
Indexed BySCIE
Language英語English
WOS Research AreaOncology
WOS SubjectOncology
WOS IDWOS:000509630300006
PublisherELSEVIER IRELAND LTD, ELSEVIER HOUSE, BROOKVALE PLAZA, EAST PARK SHANNON, CO, CLARE, 00000, IRELAND
Scopus ID2-s2.0-85076244568
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Citation statistics
Document TypeJournal article
CollectionFaculty of Health Sciences
DEPARTMENT OF BIOMEDICAL SCIENCES
Corresponding AuthorSimon Fong; Qi Zhao
Affiliation1.Cancer Center,Institute of Translational Medicine,Faculty of Health Sciences,University of Macau,Taipa,Macao,Macao
2.Department of Computer and Information Science,University of Macau,Taipa,Macau,China
3.Chongqing Industry&Trade Polytechnic,Chongqing,China
4.Zhuhai Institute of Advanced Technology Chinese Academy of Sciences,Zhuhai,China
First Author AffilicationCancer Centre
Corresponding Author AffilicationUniversity of Macau;  Cancer Centre
Recommended Citation
GB/T 7714
Shigao Huang,Jie Yang,Simon Fong,et al. Artificial intelligence in cancer diagnosis and prognosis: Opportunities and challenges[J]. Cancer Letters, 2019, 471, 61-71.
APA Shigao Huang., Jie Yang., Simon Fong., & Qi Zhao (2019). Artificial intelligence in cancer diagnosis and prognosis: Opportunities and challenges. Cancer Letters, 471, 61-71.
MLA Shigao Huang,et al."Artificial intelligence in cancer diagnosis and prognosis: Opportunities and challenges".Cancer Letters 471(2019):61-71.
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