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Classification of MLH1 Missense VUS Using Protein Structure-Based Deep Learning-Ramachandran Plot-Molecular Dynamics Simulations Method Journal article
Tam, Benjamin, Qin, Zixin, Zhao, Bojin, Sinha, Siddharth, Lei, Chon Lok, Wang, San Ming. Classification of MLH1 Missense VUS Using Protein Structure-Based Deep Learning-Ramachandran Plot-Molecular Dynamics Simulations Method[J]. International Journal of Molecular Sciences, 2024, 25(2), 850.
Authors:  Tam, Benjamin;  Qin, Zixin;  Zhao, Bojin;  Sinha, Siddharth;  Lei, Chon Lok; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:4.9/5.6 | Submit date：2024/02/22
Autoencoder  Deep Learning  Mlh1  Molecular Dynamics Simulation  Neural Network  Ramachandran Plot  Vus  
Classification of PTEN missense VUS through exascale simulations Journal article
Sinha, Siddharth, Li, Jiaheng, Tam, Benjamin, Wang, San Ming. Classification of PTEN missense VUS through exascale simulations[J]. Briefings in Bioinformatics, 2023, 24(6), bbad361.
Authors:  Sinha, Siddharth;  Li, Jiaheng;  Tam, Benjamin;  Wang, San Ming
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:6.8/7.9 | Submit date：2023/12/04
Evolution Selection  Lipid Phosphatase Activity  Md Simulations  Pten  Replica Exchange Molecular Dynamics (Remd) Simulations  Variants Of Uncertain Significance (Vus)  
Identification of deleterious variants of uncertain significance in BRCA2 BRC4 repeat through molecular dynamics simulations Journal article
Sinha, Siddharth, Qin, Zixin, Tam, Benjamin, Wang, San Ming. Identification of deleterious variants of uncertain significance in BRCA2 BRC4 repeat through molecular dynamics simulations[J]. Briefings in functional genomics, 2022, 21(3), 202-215.
Authors:  Sinha, Siddharth;  Qin, Zixin;  Tam, Benjamin;  Wang, San Ming
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:2.5/3.4 | Submit date：2022/06/10
Brca2 Brc4  Auc  Deleterious  Molecular Dynamics Simulations  Pca  Roc  Tolerated  Vus Classification  
Comprehensive identification of deleterious TP53 missense VUS variants based on their impact on TP53 structural stability Journal article
Wang, S. M.. Comprehensive identification of deleterious TP53 missense VUS variants based on their impact on TP53 structural stability[J]. Int J Mol Sci, 2021.
Authors:  Wang, S. M.
Favorite | TC[WOS]:7 TC[Scopus]:7 | Submit date：2022/07/27
Tp53  Vus  Deleterious  Molecular Dynamic Simulations  Ramachandran Plot  
Comprehensive identification of deleterious TP53 missense VUS variants based on their impact on TP53 structural stability Journal article
Benjamin Tam, Siddharth Sinha, Zixin Qin, San Ming Wang. Comprehensive identification of deleterious TP53 missense VUS variants based on their impact on TP53 structural stability[J]. International Journal of Molecular Sciences, 2021, 22(21), 11345.
Authors:  Benjamin Tam;  Siddharth Sinha;  Zixin Qin;  San Ming Wang
Favorite | TC[WOS]:7 TC[Scopus]:7 | Submit date：2021/12/08
Deleterious  Molecular Dynamic Simulations  Ramachandran Plot  Tp53  Vus  
Prevalence and reclassification of BRCA1 and BRCA2 variants in a large, unselected Chinese Han breast cancer cohort Journal article
Liu, Yun, Wang, Honglian, Wang, Xin, Liu, Jiaqi, Li, Junjian, Wang, Xiang, Zhang, Yun, Bai, Zhigang, Zhou, Qinghua, Wu, Ying, Shen, Yi, Weng, Xiaoling, Liu, Fatao, Guo, Jiancheng, Di, Lijun, Gires, Olivier, Zhang, Zhongtao, Chen, Yiding, Wang, Hongxia. Prevalence and reclassification of BRCA1 and BRCA2 variants in a large, unselected Chinese Han breast cancer cohort[J]. Journal of Hematology and Oncology, 2021, 14(1).
Authors:  Liu, Yun;  Wang, Honglian;  Wang, Xin;  Liu, Jiaqi;  Li, Junjian; et al.
Favorite | TC[WOS]:11 TC[Scopus]:19  IF:29.5/26.9 | Submit date：2022/05/13
Brca1/2  Breast Cancer  Cohort  Reclassification  Vus  
Classification of VUS and unclassified variants in BRCA1 BRCT repeats by molecular dynamics simulation Journal article
Sinha, Siddharth, Wang, San Ming. Classification of VUS and unclassified variants in BRCA1 BRCT repeats by molecular dynamics simulation[J]. Computational and Structural Biotechnology Journal, 2020, 18, 723-736.
Authors:  Sinha, Siddharth;  Wang, San Ming
Favorite | TC[WOS]:60 TC[Scopus]:67  IF:4.4/5.0 | Submit date：2022/07/27
Brca1  Brct  Vus  Unclassified  Variantsmolecular Dynamics Simulation  Pca  
Classification of VUS and unclassified variants in BRCA1 BRCT repeats by molecular dynamics simulation Journal article
Sinha,Siddharth, Wang,San Ming. Classification of VUS and unclassified variants in BRCA1 BRCT repeats by molecular dynamics simulation[J]. Computational and Structural Biotechnology Journal, 2020, 18, 723-736.
Authors:  Sinha,Siddharth;  Wang,San Ming
Favorite | TC[WOS]:60 TC[Scopus]:67  IF:4.4/5.0 | Submit date：2021/03/02
Brca1  Brct  Molecular Dynamics Simulation  Pca  Unclassified Variants  Vus