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Deubiquitinating enzymes: potential regulators of the tumor microenvironment and implications for immune evasion Review article
2024
Authors:  Hsu, Sheng Kai;  Chon-Kit Chou;  Lin, I. Ling;  Chang, Wen Tsan;  Kuo, I. Ying; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:8.2/8.0 | Submit date：2024/05/16
Cytotoxic t Cell (Ctl)  Deubiquitinating Enzymes (Dubs)  Immune Evasion  Posttranslational Modification (Ptm)  Regulatory t Cell (Treg)  Tumor Microenvironment (Tme)  Tumor-associated Macrophage (Tam)  
Therapeutic potential of TNFR2 agonists: a mechanistic perspective Journal article
Yibo Chen, Mengmeng Jiang, Xin Chen. Therapeutic potential of TNFR2 agonists: a mechanistic perspective[J]. Frontiers in Immunology, 2023, 14, 1209188.
Authors:  Yibo Chen;  Mengmeng Jiang;  Xin Chen
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:5.7/6.8 | Submit date：2023/08/31
Treg - Regulatory t Cell  Tnfr2 Agonism  Tnfr2  Tumor  Autoimmune Diseases  
Metal-Phenolic Nanomedicines Regulate T-Cell Antitumor Function for Sono-Metabolic Cancer Therapy Journal article
Yan, Jie, Li, Wenxi, Tian, Hao, Li, Bei, Yu, Xinying, Wang, Guohao, Sang, Wei, Dai, Yunlu. Metal-Phenolic Nanomedicines Regulate T-Cell Antitumor Function for Sono-Metabolic Cancer Therapy[J]. ACS Nano, 2023, 17(15), 14667-14677.
Authors:  Yan, Jie;  Li, Wenxi;  Tian, Hao;  Li, Bei;  Yu, Xinying; et al.
Favorite | TC[WOS]:24 TC[Scopus]:27  IF:15.8/16.2 | Submit date：2023/09/04
Ctla-4 Blockade  Mitochondrial Dysfunction  Sono-metabolic Therapy  Treg Cell Destabilization  Tme Reprogramming  
Distepharinamide, a novel dimeric proaporphine alkaloid from Diploclisia glaucescens, inhibits the differentiation and proliferative expansion of CD4+Foxp3+ regulatory T cells Journal article
Feng-Yang Chen, Chang-An Geng, Chon-Kit Chou, Jing-Bin Zheng, Yang Yang, Yi-Fei Wang, Tian-Ze Li, Ping Li, Ji-Jun Chen, Xin Chen*. Distepharinamide, a novel dimeric proaporphine alkaloid from Diploclisia glaucescens, inhibits the differentiation and proliferative expansion of CD4+Foxp3+ regulatory T cells[J]. Phytomedicine, 2022, 107, 154482.
Authors:  Feng-Yang Chen;  Chang-An Geng;  Chon-Kit Chou;  Jing-Bin Zheng;  Yang Yang; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:6.7/6.2 | Submit date：2023/01/30
Cancer Immunotherapy  Dimeric Proaporphine Alkaloid  Diploclisia Glaucescens  Foxp3  Treg  
Inhibiting two pore channels by tetrandrine induces expansion of TNFR2+CD4+Foxp3+ regulatory T cells Journal article
He, T., Yang, D., Li, X., Chen, S., Chen, Y., Chou, C., Trivett, A., Oppenheim, J, Chen, X.. Inhibiting two pore channels by tetrandrine induces expansion of TNFR2+CD4+Foxp3+ regulatory T cells[J]. Science Advances, 2020, 1-13.
Authors:  He, T.;  Yang, D.;  Li, X.;  Chen, S.;  Chen, Y.; et al.
Favorite |   IF:11.7/13.7 | Submit date：2022/08/30
tetrandrine  Treg  TNFR2  
中药及其活性成分对肿瘤相关调节性T细胞抑制作用研究 Journal article
Yang, Y, Chen, X. 中药及其活性成分对肿瘤相关调节性T细胞抑制作用研究[J]. 自然杂志, 2019, 1-5.
Authors:  Yang, Y;  Chen, X
Favorite | 
TNFR2-expressing CD4+Foxp3+ regulatory T cells in Cancer immunology and Immunotherapy. Journal article
Jiang, H, Li, R, Chen, Y, Hu, Y, Chen, X. TNFR2-expressing CD4+Foxp3+ regulatory T cells in Cancer immunology and Immunotherapy.[J]. progress in biology and translational science, 2019, 101-117.
Authors:  Jiang, H;  Li, R;  Chen, Y;  Hu, Y;  Chen, X
Favorite | TC[WOS]:16 TC[Scopus]:16 | Submit date：2022/08/30
Treg  Tnfr2. Cancer Immunotherapy  
Suppressive activity of human Treg cells is maintained in the presence of TNF Journal article
Zaragoza, B., Chen, X., Oppenheim, J., Baeyens, A., Gregoire, S., Chader, D., Miyara, M., Salomon, B.. Suppressive activity of human Treg cells is maintained in the presence of TNF[J]. Nature Medicine, 2016, 16-17.
Authors:  Zaragoza, B.;  Chen, X.;  Oppenheim, J.;  Baeyens, A.;  Gregoire, S.; et al.
Favorite |   IF:58.7/59.2 | Submit date：2022/08/30
Treg cells  anti-TNF  TNF  TNFR2  
Cooperation of invariant NKT cells and CD4+CD25+ T regulatory cells in prevention of autoimmune diabetes in non-obese diabetic mice treated with α-galactosylceramide Journal article
Li W., Ji F., Zhang Y., Wang Y., Yang N., Ge H., Wang F.. Cooperation of invariant NKT cells and CD4+CD25+ T regulatory cells in prevention of autoimmune diabetes in non-obese diabetic mice treated with α-galactosylceramide[J]. Acta Biochimica et Biophysica Sinica, 2008, 40(5), 381-390.
Authors:  Li W.;  Ji F.;  Zhang Y.;  Wang Y.;  Yang N.; et al.
Favorite | TC[WOS]:12 TC[Scopus]:12 | Submit date：2019/01/16
Α-galactosylceramide  Foxp3  Invariant Nkt Cell  Treg  Type 1 Diabetes  
Functional and genomic analyses of FOXP3-transduced Jurkat-T cells as regulatory T (Treg)-like cells Journal article
Kim J.-Y., Kim H.-J., Hurt E.M., Chen X., Howard O.M.Z., Farrar W.L.. Functional and genomic analyses of FOXP3-transduced Jurkat-T cells as regulatory T (Treg)-like cells[J]. Biochemical and Biophysical Research Communications, 2007, 362(1), 44-50.
Authors:  Kim J.-Y.;  Kim H.-J.;  Hurt E.M.;  Chen X.;  Howard O.M.Z.; et al.
Favorite | TC[WOS]:19 TC[Scopus]:21 | Submit date：2018/11/06
Foxp3  Jurkat-t Cells  Transduction  Treg