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Small molecule α-methylene-γ-butyrolactone, an evolutionarily conserved moiety in sesquiterpene lactones, ameliorates arthritic phenotype via interference DNA binding activity of NF-κB Journal article
Linghu, Kegang, Cui, Wenqing, Li, Taiqin, Tuo, Yueting, Wang, Dasong, Pan, Huiqi, Zhang, Tian, Lin, Ligen, Yu, Hua, Hu, Xiaoxia, Li, Haiyang, Shen, Xiangchun. Small molecule α-methylene-γ-butyrolactone, an evolutionarily conserved moiety in sesquiterpene lactones, ameliorates arthritic phenotype via interference DNA binding activity of NF-κB[J]. Acta Pharmaceutica Sinica B, 2024, 14(8), 3561-3575.
Authors:  Linghu, Kegang;  Cui, Wenqing;  Li, Taiqin;  Tuo, Yueting;  Wang, Dasong; et al.
Favorite | TC[WOS]:3 TC[Scopus]:4  IF:14.7/14.1 | Submit date:2024/05/16
A-methylene-g-  Butyrolactone  Rheumatoid Arthritis  Nf-kb P65  Synovial  Microenvironment  Sesquiterpene Lactones  
Microneedle-assisted dual delivery of PUMA gene and celastrol for synergistic therapy of rheumatoid arthritis through restoring synovial homeostasis Journal article
Hua, Peng, Liang, Ruifeng, Yang, Suleixin, Tu, Yanbei, Chen, Meiwan. Microneedle-assisted dual delivery of PUMA gene and celastrol for synergistic therapy of rheumatoid arthritis through restoring synovial homeostasis[J]. Bioactive Materials, 2024, 36, 83-95.
Authors:  Hua, Peng;  Liang, Ruifeng;  Yang, Suleixin;  Tu, Yanbei;  Chen, Meiwan
Favorite | TC[WOS]:60 TC[Scopus]:7  IF:18.0/18.2 | Submit date:2024/05/16
Anti-inflammation  Celastrol  Fibroblast-like Synoviocyte Apoptosis  Puma  Rheumatoid Arthritis  
Cayratia albifolia C.L.Li exerts anti-rheumatoid arthritis effect by inhibiting macrophage activation and neutrophil extracellular traps (NETs) Journal article
Wang, Wei, Zhang, Zai Qi, Zhang, Yi Chi, Wu, Yi Qiang, Yang, Zhuo, Zheng, Yong Zhe, Lu, Jia Hong, Tu, Peng Fei, Zeng, Ke Wu. Cayratia albifolia C.L.Li exerts anti-rheumatoid arthritis effect by inhibiting macrophage activation and neutrophil extracellular traps (NETs)[J]. Chinese Medicine (United Kingdom), 2024, 19(1), 42.
Authors:  Wang, Wei;  Zhang, Zai Qi;  Zhang, Yi Chi;  Wu, Yi Qiang;  Yang, Zhuo; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:5.3/5.5 | Submit date:2024/05/16
Cayratia Albifolia C.l.li  Macrophage  Netosis  Pi3k-akt Pathway  Rheumatoid Arthritis  
Carrier-Free Gambogic Acid Dimer Self-Assembly Nanomedicines for Rheumatoid Arthritis Treatment Journal article
Liu, Yuling, Nie, Xin, Wu, Yihan, Lin, Longfei, Liao, Qian, Li, Jingjing, Lee, Simon Ming Yuen, Li, Hui, Zhang, Jinming. Carrier-Free Gambogic Acid Dimer Self-Assembly Nanomedicines for Rheumatoid Arthritis Treatment[J]. International Journal of Nanomedicine, 2023, 18, 5457-5472.
Authors:  Liu, Yuling;  Nie, Xin;  Wu, Yihan;  Lin, Longfei;  Liao, Qian; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4 | Submit date:2024/02/22
Carrier-free Nanoparticles  Gambogic Acid Dimers  Macrophage  Osteoclast  Rheumatoid Arthritis  Self-assembly  
Reactive oxygen species and nitric oxide scavenging nanoparticles alleviating rheumatoid arthritis through adjusting the seeds and growing soils Journal article
Peng Hua, Ruifeng Liang, Yanbei Tu, Yuying Yin, Man-Kay Law, Meiwan Chen. Reactive oxygen species and nitric oxide scavenging nanoparticles alleviating rheumatoid arthritis through adjusting the seeds and growing soils[J]. Acta Pharmaceutica Sinica B, 2023, 13(12), 5016-5029.
Authors:  Peng Hua;  Ruifeng Liang;  Yanbei Tu;  Yuying Yin;  Man-Kay Law; et al.
Favorite | TC[WOS]:8 TC[Scopus]:9  IF:14.7/14.1 | Submit date:2023/08/21
Anti-inflammatory  Bilirubin  Cartilage Protection  Jak-stat Pathway  Notopterol  O-phenylenediamine  Rheumatoid Arthritis  Ros And No Scavenging  
Leocarpinolide B Attenuates Collagen Type II-Induced Arthritis by Inhibiting DNA Binding Activity of NF-κB Journal article
Linghu, Ke Gang, Zhao, Guan Ding, Zhang, Dai Yan, Xiong, Shi Hang, Wu, Guo Ping, Shen, Li Yu, Cui, Wen Qing, Zhang, Tian, Hu, Yuan Jia, Guo, Bing, Shen, Xiang Chun, Yu, Hua. Leocarpinolide B Attenuates Collagen Type II-Induced Arthritis by Inhibiting DNA Binding Activity of NF-κB[J]. Molecules (Basel, Switzerland), 2023, 28(10), 4241.
Authors:  Linghu, Ke Gang;  Zhao, Guan Ding;  Zhang, Dai Yan;  Xiong, Shi Hang;  Wu, Guo Ping; et al.
Favorite | TC[WOS]:4 TC[Scopus]:3  IF:4.2/4.6 | Submit date:2023/06/05
Leocarpinolide b  Nf-κb P65  Rheumatoid Arthritis  Sesquiterpene Lactone  Synovitis  
Sinomenine hydrochloride bidirectionally inhibits progression of tumor and autoimmune diseases by regulating AMPK pathway. Journal article
Li RunZe, Guan XiaoXiang, Wang XuanRun, Bao WeiQian, Lian LiRong, Choi Seong Wang, Zhang FangYuan, Yan PeiYu, Leung Elaine Lai Han, Pan HuDan, Liu Liang. Sinomenine hydrochloride bidirectionally inhibits progression of tumor and autoimmune diseases by regulating AMPK pathway.[J]. Phytomedicine, 2023, 114, 154751.
Authors:  Li RunZe;  Guan XiaoXiang;  Wang XuanRun;  Bao WeiQian;  Lian LiRong; et al.
Favorite | TC[WOS]:9 TC[Scopus]:11  IF:6.7/6.2 | Submit date:2023/06/14
Sinomenine Hydrochloride  Ampk  Nsclc  Rheumatoid Arthritis  
pH-sensitive nano-polyelectrolyte complexes with arthritic macrophage-targeting delivery of triptolide Journal article
Jia, Xin Li, Meng, Jiao Zhang, Jin, Feng Shi, Sheng, Peng Wang, Xue, Mei Zhong, Yi, Han Wu, Yan, Qu, Hui, Le Gao, Jin, Ming Zhang. pH-sensitive nano-polyelectrolyte complexes with arthritic macrophage-targeting delivery of triptolide[J]. International Journal of Pharmaceutics, 2023, 632, 122572.
Authors:  Jia, Xin Li;  Meng, Jiao Zhang;  Jin, Feng Shi;  Sheng, Peng Wang;  Xue, Mei Zhong; et al.
Favorite | TC[WOS]:11 TC[Scopus]:9  IF:5.3/5.6 | Submit date:2023/02/22
Triptolide, Polyelectrolyte Complexes  Rheumatoid Arthritis  Macrophage  Pbae  
The role of non-coding RNAs (miRNA and lncRNA) in the clinical management of rheumatoid arthritis Journal article
Yang, Jiujie, Li, Zhi, Wang, Linna, Yun, Xiaoyun, Zeng, Yaling, Ng, Jerome P.L., Lo, Hanghong, Wang, Yan, Zhang, Kaixi, Law, Betty Yuen Kwan, Wong, Vincent Kam Wai. The role of non-coding RNAs (miRNA and lncRNA) in the clinical management of rheumatoid arthritis[J]. Pharmacological Research, 2022, 186.
Authors:  Yang, Jiujie;  Li, Zhi;  Wang, Linna;  Yun, Xiaoyun;  Zeng, Yaling; et al.
Favorite | TC[WOS]:21 TC[Scopus]:17  IF:9.1/9.0 | Submit date:2023/01/30
Clinical Management  Non-coding Rna (ncRna)  Rheumatoid Arthritis (Ra)  
The Correlation Between Decreased Ornithine Level and Alleviation of Rheumatoid Arthritis Patients Assessed by a Randomized, Placebo-Controlled, Double-Blind Clinical Trial of Sinomenine Journal article
Shi, Ying, Pan, Hu Dan, Wu, Jian Lin, Zou, Qing Hua, Xie, Xin Yi, Li, Hong Gang, Zhou, Hua, Bian, Xi Qing, Leng, Wen Fei, Wang, Can Jian, Wang, Ya Feng, Fang, Yong Fei, Liu, Liang. The Correlation Between Decreased Ornithine Level and Alleviation of Rheumatoid Arthritis Patients Assessed by a Randomized, Placebo-Controlled, Double-Blind Clinical Trial of Sinomenine[J]. Engineering, 2022, 16, 93-99.
Authors:  Shi, Ying;  Pan, Hu Dan;  Wu, Jian Lin;  Zou, Qing Hua;  Xie, Xin Yi; et al.
Favorite | TC[WOS]:5 TC[Scopus]:6  IF:10.1/11.6 | Submit date:2023/01/30
Efficacy  Inflammatory Biomarker  Rheumatoid Arthritis  Safety  Sinomenine