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Small molecule α-methylene-γ-butyrolactone, an evolutionarily conserved moiety in sesquiterpene lactones, ameliorates arthritic phenotype via interference DNA binding activity of NF-κB
Journal article
Linghu, Kegang, Cui, Wenqing, Li, Taiqin, Tuo, Yueting, Wang, Dasong, Pan, Huiqi, Zhang, Tian, Lin, Ligen, Yu, Hua, Hu, Xiaoxia, Li, Haiyang, Shen, Xiangchun. Small molecule α-methylene-γ-butyrolactone, an evolutionarily conserved moiety in sesquiterpene lactones, ameliorates arthritic phenotype via interference DNA binding activity of NF-κB[J]. Acta Pharmaceutica Sinica B, 2024, 14(8), 3561-3575.
Authors:
Linghu, Kegang
;
Cui, Wenqing
;
Li, Taiqin
;
Tuo, Yueting
;
Wang, Dasong
; et al.
Favorite
|
TC[WOS]:
3
TC[Scopus]:
4
IF:
14.7
/
14.1
|
Submit date:2024/05/16
A-methylene-g-
Butyrolactone
Rheumatoid Arthritis
Nf-kb P65
Synovial
Microenvironment
Sesquiterpene Lactones
Microneedle-assisted dual delivery of PUMA gene and celastrol for synergistic therapy of rheumatoid arthritis through restoring synovial homeostasis
Journal article
Hua, Peng, Liang, Ruifeng, Yang, Suleixin, Tu, Yanbei, Chen, Meiwan. Microneedle-assisted dual delivery of PUMA gene and celastrol for synergistic therapy of rheumatoid arthritis through restoring synovial homeostasis[J]. Bioactive Materials, 2024, 36, 83-95.
Authors:
Hua, Peng
;
Liang, Ruifeng
;
Yang, Suleixin
;
Tu, Yanbei
;
Chen, Meiwan
Favorite
|
TC[WOS]:
60
TC[Scopus]:
7
IF:
18.0
/
18.2
|
Submit date:2024/05/16
Anti-inflammation
Celastrol
Fibroblast-like Synoviocyte Apoptosis
Puma
Rheumatoid Arthritis
Cayratia albifolia C.L.Li exerts anti-rheumatoid arthritis effect by inhibiting macrophage activation and neutrophil extracellular traps (NETs)
Journal article
Wang, Wei, Zhang, Zai Qi, Zhang, Yi Chi, Wu, Yi Qiang, Yang, Zhuo, Zheng, Yong Zhe, Lu, Jia Hong, Tu, Peng Fei, Zeng, Ke Wu. Cayratia albifolia C.L.Li exerts anti-rheumatoid arthritis effect by inhibiting macrophage activation and neutrophil extracellular traps (NETs)[J]. Chinese Medicine (United Kingdom), 2024, 19(1), 42.
Authors:
Wang, Wei
;
Zhang, Zai Qi
;
Zhang, Yi Chi
;
Wu, Yi Qiang
;
Yang, Zhuo
; et al.
Favorite
|
TC[WOS]:
2
TC[Scopus]:
2
IF:
5.3
/
5.5
|
Submit date:2024/05/16
Cayratia Albifolia C.l.li
Macrophage
Netosis
Pi3k-akt Pathway
Rheumatoid Arthritis
Carrier-Free Gambogic Acid Dimer Self-Assembly Nanomedicines for Rheumatoid Arthritis Treatment
Journal article
Liu, Yuling, Nie, Xin, Wu, Yihan, Lin, Longfei, Liao, Qian, Li, Jingjing, Lee, Simon Ming Yuen, Li, Hui, Zhang, Jinming. Carrier-Free Gambogic Acid Dimer Self-Assembly Nanomedicines for Rheumatoid Arthritis Treatment[J]. International Journal of Nanomedicine, 2023, 18, 5457-5472.
Authors:
Liu, Yuling
;
Nie, Xin
;
Wu, Yihan
;
Lin, Longfei
;
Liao, Qian
; et al.
Favorite
|
TC[WOS]:
4
TC[Scopus]:
4
|
Submit date:2024/02/22
Carrier-free Nanoparticles
Gambogic Acid Dimers
Macrophage
Osteoclast
Rheumatoid Arthritis
Self-assembly
Reactive oxygen species and nitric oxide scavenging nanoparticles alleviating rheumatoid arthritis through adjusting the seeds and growing soils
Journal article
Peng Hua, Ruifeng Liang, Yanbei Tu, Yuying Yin, Man-Kay Law, Meiwan Chen. Reactive oxygen species and nitric oxide scavenging nanoparticles alleviating rheumatoid arthritis through adjusting the seeds and growing soils[J]. Acta Pharmaceutica Sinica B, 2023, 13(12), 5016-5029.
Authors:
Peng Hua
;
Ruifeng Liang
;
Yanbei Tu
;
Yuying Yin
;
Man-Kay Law
; et al.
Favorite
|
TC[WOS]:
8
TC[Scopus]:
9
IF:
14.7
/
14.1
|
Submit date:2023/08/21
Anti-inflammatory
Bilirubin
Cartilage Protection
Jak-stat Pathway
Notopterol
O-phenylenediamine
Rheumatoid Arthritis
Ros And No Scavenging
Leocarpinolide B Attenuates Collagen Type II-Induced Arthritis by Inhibiting DNA Binding Activity of NF-κB
Journal article
Linghu, Ke Gang, Zhao, Guan Ding, Zhang, Dai Yan, Xiong, Shi Hang, Wu, Guo Ping, Shen, Li Yu, Cui, Wen Qing, Zhang, Tian, Hu, Yuan Jia, Guo, Bing, Shen, Xiang Chun, Yu, Hua. Leocarpinolide B Attenuates Collagen Type II-Induced Arthritis by Inhibiting DNA Binding Activity of NF-κB[J]. Molecules (Basel, Switzerland), 2023, 28(10), 4241.
Authors:
Linghu, Ke Gang
;
Zhao, Guan Ding
;
Zhang, Dai Yan
;
Xiong, Shi Hang
;
Wu, Guo Ping
; et al.
Favorite
|
TC[WOS]:
4
TC[Scopus]:
3
IF:
4.2
/
4.6
|
Submit date:2023/06/05
Leocarpinolide b
Nf-κb P65
Rheumatoid Arthritis
Sesquiterpene Lactone
Synovitis
Sinomenine hydrochloride bidirectionally inhibits progression of tumor and autoimmune diseases by regulating AMPK pathway.
Journal article
Li RunZe, Guan XiaoXiang, Wang XuanRun, Bao WeiQian, Lian LiRong, Choi Seong Wang, Zhang FangYuan, Yan PeiYu, Leung Elaine Lai Han, Pan HuDan, Liu Liang. Sinomenine hydrochloride bidirectionally inhibits progression of tumor and autoimmune diseases by regulating AMPK pathway.[J]. Phytomedicine, 2023, 114, 154751.
Authors:
Li RunZe
;
Guan XiaoXiang
;
Wang XuanRun
;
Bao WeiQian
;
Lian LiRong
; et al.
Favorite
|
TC[WOS]:
9
TC[Scopus]:
11
IF:
6.7
/
6.2
|
Submit date:2023/06/14
Sinomenine Hydrochloride
Ampk
Nsclc
Rheumatoid Arthritis
pH-sensitive nano-polyelectrolyte complexes with arthritic macrophage-targeting delivery of triptolide
Journal article
Jia, Xin Li, Meng, Jiao Zhang, Jin, Feng Shi, Sheng, Peng Wang, Xue, Mei Zhong, Yi, Han Wu, Yan, Qu, Hui, Le Gao, Jin, Ming Zhang. pH-sensitive nano-polyelectrolyte complexes with arthritic macrophage-targeting delivery of triptolide[J]. International Journal of Pharmaceutics, 2023, 632, 122572.
Authors:
Jia, Xin Li
;
Meng, Jiao Zhang
;
Jin, Feng Shi
;
Sheng, Peng Wang
;
Xue, Mei Zhong
; et al.
Favorite
|
TC[WOS]:
11
TC[Scopus]:
9
IF:
5.3
/
5.6
|
Submit date:2023/02/22
Triptolide, Polyelectrolyte Complexes
Rheumatoid Arthritis
Macrophage
Pbae
The role of non-coding RNAs (miRNA and lncRNA) in the clinical management of rheumatoid arthritis
Journal article
Yang, Jiujie, Li, Zhi, Wang, Linna, Yun, Xiaoyun, Zeng, Yaling, Ng, Jerome P.L., Lo, Hanghong, Wang, Yan, Zhang, Kaixi, Law, Betty Yuen Kwan, Wong, Vincent Kam Wai. The role of non-coding RNAs (miRNA and lncRNA) in the clinical management of rheumatoid arthritis[J]. Pharmacological Research, 2022, 186.
Authors:
Yang, Jiujie
;
Li, Zhi
;
Wang, Linna
;
Yun, Xiaoyun
;
Zeng, Yaling
; et al.
Favorite
|
TC[WOS]:
21
TC[Scopus]:
17
IF:
9.1
/
9.0
|
Submit date:2023/01/30
Clinical Management
Non-coding Rna (ncRna)
Rheumatoid Arthritis (Ra)
The Correlation Between Decreased Ornithine Level and Alleviation of Rheumatoid Arthritis Patients Assessed by a Randomized, Placebo-Controlled, Double-Blind Clinical Trial of Sinomenine
Journal article
Shi, Ying, Pan, Hu Dan, Wu, Jian Lin, Zou, Qing Hua, Xie, Xin Yi, Li, Hong Gang, Zhou, Hua, Bian, Xi Qing, Leng, Wen Fei, Wang, Can Jian, Wang, Ya Feng, Fang, Yong Fei, Liu, Liang. The Correlation Between Decreased Ornithine Level and Alleviation of Rheumatoid Arthritis Patients Assessed by a Randomized, Placebo-Controlled, Double-Blind Clinical Trial of Sinomenine[J]. Engineering, 2022, 16, 93-99.
Authors:
Shi, Ying
;
Pan, Hu Dan
;
Wu, Jian Lin
;
Zou, Qing Hua
;
Xie, Xin Yi
; et al.
Favorite
|
TC[WOS]:
5
TC[Scopus]:
6
IF:
10.1
/
11.6
|
Submit date:2023/01/30
Efficacy
Inflammatory Biomarker
Rheumatoid Arthritis
Safety
Sinomenine