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Comprehensive classification of TP53 somatic missense variants based on their impact on p53 structural stability Journal article
Benjamin Tam, Philip Naderev P. Lagniton, Mariano da Luz, Bojin Zhao, Siddharth Sinha, Chon Lok Lei, San Ming Wang. Comprehensive classification of TP53 somatic missense variants based on their impact on p53 structural stability[J]. Briefings in Bioinformatics, 2024, 25(5), bbae400.
Authors:  Benjamin Tam;  Philip Naderev P. Lagniton;  Mariano da Luz;  Bojin Zhao;  Siddharth Sinha; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:6.8/7.9 | Submit date：2024/08/07
Ramachandran Plot  Molecular Dynamics Simulations  Tp53  Somatic Missense Variants  
Classification of MLH1 Missense VUS Using Protein Structure-Based Deep Learning-Ramachandran Plot-Molecular Dynamics Simulations Method Journal article
Tam, Benjamin, Qin, Zixin, Zhao, Bojin, Sinha, Siddharth, Lei, Chon Lok, Wang, San Ming. Classification of MLH1 Missense VUS Using Protein Structure-Based Deep Learning-Ramachandran Plot-Molecular Dynamics Simulations Method[J]. International Journal of Molecular Sciences, 2024, 25(2), 850.
Authors:  Tam, Benjamin;  Qin, Zixin;  Zhao, Bojin;  Sinha, Siddharth;  Lei, Chon Lok; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:4.9/5.6 | Submit date：2024/02/22
Autoencoder  Deep Learning  Mlh1  Molecular Dynamics Simulation  Neural Network  Ramachandran Plot  Vus  
Comprehensive identification of deleterious TP53 missense VUS variants based on their impact on TP53 structural stability Journal article
Wang, S. M.. Comprehensive identification of deleterious TP53 missense VUS variants based on their impact on TP53 structural stability[J]. Int J Mol Sci, 2021.
Authors:  Wang, S. M.
Favorite | TC[WOS]:7 TC[Scopus]:7 | Submit date：2022/07/27
Tp53  Vus  Deleterious  Molecular Dynamic Simulations  Ramachandran Plot  
Comprehensive identification of deleterious TP53 missense VUS variants based on their impact on TP53 structural stability Journal article
Benjamin Tam, Siddharth Sinha, Zixin Qin, San Ming Wang. Comprehensive identification of deleterious TP53 missense VUS variants based on their impact on TP53 structural stability[J]. International Journal of Molecular Sciences, 2021, 22(21), 11345.
Authors:  Benjamin Tam;  Siddharth Sinha;  Zixin Qin;  San Ming Wang
Favorite | TC[WOS]:7 TC[Scopus]:7 | Submit date：2021/12/08
Deleterious  Molecular Dynamic Simulations  Ramachandran Plot  Tp53  Vus  
Combining Ramachandran plot and molecular dynamics simulation for structural-based variant classification: Using TP53 variants as model Journal article
Tam,Benjamin, Sinha,Siddharth, Wang,San Ming. Combining Ramachandran plot and molecular dynamics simulation for structural-based variant classification: Using TP53 variants as model[J]. Computational and Structural Biotechnology Journal, 2020, 18, 4033-4039.
Authors:  Tam,Benjamin;  Sinha,Siddharth;  Wang,San Ming
Favorite | TC[WOS]:32 TC[Scopus]:35 | Submit date：2021/03/02
Molecular Dynamic Simulation  Pathogenic  Protein Structure  Ramachandran Plot  Tp53  Variant Of Uncertain Significance  
Combining Ramachandran Plot and Molecular Dynamics Simulation for structural-based variant classification: using TP53 variants as model Journal article
Tam,Benjamin, Sinha,Siddharth, Wang,San Ming. Combining Ramachandran Plot and Molecular Dynamics Simulation for structural-based variant classification: using TP53 variants as model[J]. Computational and Structural Biotechnology Journal, 2020, 18, 4033-4039.
Authors:  Tam,Benjamin;  Sinha,Siddharth;  Wang,San Ming
Favorite | TC[WOS]:32 TC[Scopus]:36 | Submit date：2022/07/27
Molecular Dynamic Simulation  Pathogenic  Protein Structure  Ramachandran Plot  Tp53  Variant Of Uncertain Significance