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Leak current, even with gigaohm seals, can cause misinterpretation of stem cell-derived cardiomyocyte action potential recordings Journal article
Alexander P Clark, Michael Clerx, Siyu Wei, Chon Lok Lei, Teun P de Boer, Gary R Mirams, David J Christini, Trine Krogh-Madsen. Leak current, even with gigaohm seals, can cause misinterpretation of stem cell-derived cardiomyocyte action potential recordings[J]. EUROPACE, 2023, 25(9), euad243.
Authors:  Alexander P Clark;  Michael Clerx;  Siyu Wei;  Chon Lok Lei;  Teun P de Boer; et al.
Favorite | TC[WOS]:4 TC[Scopus]:5  IF:7.9/6.3 | Submit date：2023/09/04
Arrhythmias  Computer Simulation  Induced Pluripotent Stem Cells  Ion Channels  Patch Clamp  
Model-driven optimal experimental design for calibrating cardiac electrophysiology models Journal article
Lei,Chon Lok, Clerx,Michael, Gavaghan,David J., Mirams,Gary R.. Model-driven optimal experimental design for calibrating cardiac electrophysiology models[J]. Computer Methods and Programs in Biomedicine, 2023, 240, 107690.
Authors:  Lei,Chon Lok;  Clerx,Michael;  Gavaghan,David J.;  Mirams,Gary R.
Favorite | TC[WOS]:5 TC[Scopus]:5  IF:4.9/5.5 | Submit date：2023/08/03
Action Potential  Electrophysiology  Mathematical Modelling  Model Calibration  Optimal Experimental Design  Patch Clamp  
A nonlinear and time-dependent leak current in the presence of calcium fluoride patch-clamp seal enhancer Journal article
Lei, Chon Lok, Fabbri, Alan, Whittaker, Dominic G., Clerx, Michael, Windley, Monique J., Hill, Adam P., Mirams, Gary R., de Boer, Teun P.. A nonlinear and time-dependent leak current in the presence of calcium fluoride patch-clamp seal enhancer[J]. Wellcome Open Research, 2021, 5, 152.
Authors:  Lei, Chon Lok;  Fabbri, Alan;  Whittaker, Dominic G.;  Clerx, Michael;  Windley, Monique J.; et al.
Favorite | TC[Scopus]:5 | Submit date：2021/11/30
Automated Patch  Electrophysiology  Leak Current  Patch Clamp  Seal Enhancer