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Faculty of Healt... [1]
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LEI CHON LOK [1]
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Journal article [1]
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2023 [1]
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英語English [1]
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Frontiers in Pha... [1]
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Importance of modelling hERG binding in predicting drug-induced action potential prolongations for drug safety assessment
Journal article
Farm,Hui Jia, Clerx,Michael, Cooper,Fergus, Polonchuk,Liudmila, Wang,Ken, Gavaghan,David J., Lei,Chon Lok. Importance of modelling hERG binding in predicting drug-induced action potential prolongations for drug safety assessment[J]. Frontiers in Pharmacology, 2023, 14, 1110555.
Authors: ; et al.
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Submit date：2023/08/03
Drug Binding
Drug Trapping
Ic50 (50% Inhibition Concentration)
Mathematical Modelling
Herg Channel
Action Potential Predictions
