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Structure and activity relationship analysis of xanthones from mangosteen: Identifying garcinone E as a potent dual EGFR and VEGFR2 inhibitor
Journal article
Li, Jingjing, Nie, Xin, Panthakarn Rangsinth,, Wu, Xiaoping, Zheng, Chengwen, Cheng, Yanfen, Shiu, Polly Ho Ting, Li, Renkai, Lee, Simon Ming Yuen, Fu, Chaomei, Zhang, Jinming, Leung, George Pak Heng. Structure and activity relationship analysis of xanthones from mangosteen: Identifying garcinone E as a potent dual EGFR and VEGFR2 inhibitor[J]. Phytomedicine, 2024, 122, 155140.
Authors:
Li, Jingjing
;
Nie, Xin
;
Panthakarn Rangsinth,
;
Wu, Xiaoping
;
Zheng, Chengwen
; et al.
Favorite
|
TC[WOS]:
2
TC[Scopus]:
3
IF:
6.7
/
6.2
|
Submit date:2024/02/22
Epidermal Growth Factor Receptor
Garcinone e
Mangosteen
Vascular Endothelial Growth Factor Receptor 2
Xanthones
Gαq Is the Specific Mediator of PAR-1 Transactivation of Kinase Receptors in Vascular Smooth Muscle Cells
Journal article
Danielle Kamato, Mai Gabr, Hirushi Kumarapperuma, Zheng J. Chia, Wenhua Zheng, Suowen Xu, Narin Osman, Peter J. Little. Gαq Is the Specific Mediator of PAR-1 Transactivation of Kinase Receptors in Vascular Smooth Muscle Cells[J]. International Journal of Molecular Sciences, 2022, 23(22), 14425.
Authors:
Danielle Kamato
;
Mai Gabr
;
Hirushi Kumarapperuma
;
Zheng J. Chia
;
Wenhua Zheng
; et al.
Favorite
|
TC[WOS]:
2
TC[Scopus]:
3
|
Submit date:2023/01/31
Epidermal Growth Factor Receptor
Transforming Growth Factor Type i Receptor
Transactivation Dependent
Gpcr
Thrombin
Proteoglycans
Oriented Layered Graphene Oxide Pad Favoring High Loading Capacity and Stability for High-Throughput Chemical Screening
Journal article
Zhou, Mingyue, Li, Yan, Huang, Chuanjin, Wang, Cairen, Liu, Qinghua, Deng, Qibo, Zhang, Huixia, Yin, Tianpeng, Zhu, Guoyuan, Wang, Caiyun, Zhao, Yunfeng, Zhang, Wei. Oriented Layered Graphene Oxide Pad Favoring High Loading Capacity and Stability for High-Throughput Chemical Screening[J]. Advanced Materials Technologies, 2022, 7(9).
Authors:
Zhou, Mingyue
;
Li, Yan
;
Huang, Chuanjin
;
Wang, Cairen
;
Liu, Qinghua
; et al.
Favorite
|
TC[WOS]:
4
TC[Scopus]:
4
IF:
6.4
/
8.0
|
Submit date:2023/01/30
Comfrey
Epidermal Growth Factor Receptor
Ligand Fishing
Oriented Layered Graphene Oxide Pad
Disruption of Epidermal Growth Factor Receptor but Not EGF Blocks Follicle Activation in Zebrafish Ovary
Journal article
Yanlong Song, Weiting Chen, Bo Zhu, Wei Ge. Disruption of Epidermal Growth Factor Receptor but Not EGF Blocks Follicle Activation in Zebrafish Ovary[J]. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2022, 9, 750888.
Authors:
Yanlong Song
;
Weiting Chen
;
Bo Zhu
;
Wei Ge
Favorite
|
TC[WOS]:
18
TC[Scopus]:
19
IF:
4.6
/
5.2
|
Submit date:2022/02/21
Epidermal Growth Factor Egf
Egf Receptor Egfr
Gonadal Development
Folliculogenesis
Spermatogenesis
Zebrafish
Drug resistance of targeted therapy for advanced non-small cell lung cancer harbored EGFR mutation: from mechanism analysis to clinical strategy
Journal article
Yuxin Zhao, Haiyong Wang, Chengwei He. Drug resistance of targeted therapy for advanced non-small cell lung cancer harbored EGFR mutation: from mechanism analysis to clinical strategy[J]. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2021, 147(12), 3653-3664.
Authors:
Yuxin Zhao
;
Haiyong Wang
;
Chengwei He
Favorite
|
TC[WOS]:
20
TC[Scopus]:
19
IF:
2.7
/
3.1
|
Submit date:2021/12/08
Non-small Cell Lung Cancer
Targeted Therapy
Epidermal Growth Factor Receptor-tyrosine Kinase Inhibitor
Drug Resistance
Inhibition of pyruvate dehydrogenase kinase 1 enhances the anti-cancer effect of EGFR tyrosine kinase inhibitors in non-small cell lung cancer
Journal article
Yang, Zheng, Zhang, Shao-Lin, Hu, Xiaohui, Tam, Kin Yip. Inhibition of pyruvate dehydrogenase kinase 1 enhances the anti-cancer effect of EGFR tyrosine kinase inhibitors in non-small cell lung cancer[J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 2018, 838, 41-52.
Authors:
Yang, Zheng
;
Zhang, Shao-Lin
;
Hu, Xiaohui
;
Tam, Kin Yip
Favorite
|
TC[WOS]:
27
TC[Scopus]:
27
IF:
4.2
/
4.3
|
Submit date:2018/10/30
Dichloroacetophenone
Epidermal Growth Factor Receptor
Tyrosine Kinase Inhibitor
Synergism
Hypoxia
Oxidative Phosphorylation
Autophagic degradation of epidermal growth factor receptor in gefitinib-resistant lung cancer by celastrol
Journal article
Xu S.-W., Law B.Y.K., Mok S.W.F., Leung E.L.H., Fan X.X., Coghi P.S., Zeng W., Leung C.-H., Ma D.-L., Liu L., Wong V.K.W.. Autophagic degradation of epidermal growth factor receptor in gefitinib-resistant lung cancer by celastrol[J]. International Journal of Oncology, 2016, 49(4), 1576-1588.
Authors:
Xu S.-W.
;
Law B.Y.K.
;
Mok S.W.F.
;
Leung E.L.H.
;
Fan X.X.
; et al.
Favorite
|
TC[WOS]:
26
TC[Scopus]:
29
|
Submit date:2018/11/06
Autophagy
Calcium
Celastrol
Epidermal Growth Factor Receptor
Gefitinib-resistant Lung Cancer
Anti-cancer synergy of dichloroacetate and EGFR tyrosine kinase inhibitors in NSCLC cell lines
Journal article
Yang,Zheng, Tam,Kin Y.. Anti-cancer synergy of dichloroacetate and EGFR tyrosine kinase inhibitors in NSCLC cell lines[J]. European Journal of Pharmacology, 2016, 789, 458-467.
Authors:
Yang,Zheng
;
Tam,Kin Y.
Favorite
|
TC[WOS]:
31
TC[Scopus]:
31
IF:
4.2
/
4.3
|
Submit date:2021/03/04
Dichloroacetate
Drug Combination
Epidermal Growth Factor Receptor
Erlotinib
Gefitinib
Pyruvate Dehydrogenase Kinase
Anti-cancer synergy of dichloroacetate and EGFR tyrosine kinase inhibitors in NSCLC cell lines
Journal article
Yang Z., Tam K.Y.. Anti-cancer synergy of dichloroacetate and EGFR tyrosine kinase inhibitors in NSCLC cell lines[J]. European Journal of Pharmacology, 2016, 789, 458-467.
Authors:
Yang Z.
;
Tam K.Y.
Favorite
|
TC[WOS]:
31
TC[Scopus]:
31
|
Submit date:2018/12/18
Dichloroacetate
Drug Combination
Epidermal Growth Factor Receptor
Erlotinib
Gefitinib
Pyruvate Dehydrogenase Kinase
Prognostic significance of combining VEGFA, FLT1 and KDR mRNA expression in lung cancer
Journal article
Zhang S.-D., McCrudden C.M., Kwok H.F.. Prognostic significance of combining VEGFA, FLT1 and KDR mRNA expression in lung cancer[J]. Oncology Letters, 2015, 10(3), 1893-1901.
Authors:
Zhang S.-D.
;
McCrudden C.M.
;
Kwok H.F.
Favorite
|
TC[WOS]:
20
TC[Scopus]:
23
|
Submit date:2018/12/19
Angiogenesis
Fms‑related Tyrosine Kinase 1
Kinase Insert Domain Receptor
Lung Cancer
Survival
Vascular Epidermal Growth Factor a