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Enzyme/ROS dual-sensitive nanoplatform with on-demand Celastrol release capacity for enhanced ulcerative colitis therapy by ROS scavenging, microbiota rebalancing, inflammation alleviating Journal article
Shi, Jinfeng, Zhou, Jiahui, Liu, Bo, Lin, Kezhou, Xie, Xingliang, Han, Xue, Sheng, Yanmei, Liu, Yihan, He, Congjian, Zhou, Yujin, Zhu, Nan, Yang, Qian, Luo, Ruifeng, Li, Yi. Enzyme/ROS dual-sensitive nanoplatform with on-demand Celastrol release capacity for enhanced ulcerative colitis therapy by ROS scavenging, microbiota rebalancing, inflammation alleviating[J]. Journal of Nanobiotechnology, 2024, 22(1), 437.
Authors:  Shi, Jinfeng;  Zhou, Jiahui;  Liu, Bo;  Lin, Kezhou;  Xie, Xingliang; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:10.6/11.4 | Submit date：2024/08/05
Celastrol  Enzyme/ros-triggered Controlled Release  Ros Scavengers  Ulcerative Colitis  
Microneedle-assisted dual delivery of PUMA gene and celastrol for synergistic therapy of rheumatoid arthritis through restoring synovial homeostasis Journal article
Hua, Peng, Liang, Ruifeng, Yang, Suleixin, Tu, Yanbei, Chen, Meiwan. Microneedle-assisted dual delivery of PUMA gene and celastrol for synergistic therapy of rheumatoid arthritis through restoring synovial homeostasis[J]. Bioactive Materials, 2024, 36, 83-95.
Authors:  Hua, Peng;  Liang, Ruifeng;  Yang, Suleixin;  Tu, Yanbei;  Chen, Meiwan
Favorite | TC[WOS]:60 TC[Scopus]:7  IF:18.0/18.2 | Submit date：2024/05/16
Anti-inflammation  Celastrol  Fibroblast-like Synoviocyte Apoptosis  Puma  Rheumatoid Arthritis  
Celastrol attenuates hepatitis C virus translation and inflammatory response in mice by suppressing heat shock protein 90β Journal article
Shao-Ru Chen, Zheng-Qing Li, Jun Xu, Mo-Yu Ding, Yaming Shan, Yung-Chi Cheng, Gao-Xiao Zhang, Ye-Wei Sun, Yuqiang Wang, Wang Y(王穎). Celastrol attenuates hepatitis C virus translation and inflammatory response in mice by suppressing heat shock protein 90β[J]. ACTA PHARMACOLOGICA SINICA, 2023, 44, 1637-1648.
Authors:  Shao-Ru Chen;  Zheng-Qing Li;  Jun Xu;  Mo-Yu Ding;  Yaming Shan; et al.
Favorite | TC[WOS]:6 TC[Scopus]:6  IF:6.9/7.6 | Submit date：2023/07/06
Celastrol  Heat Shock Protein 90β  Hepatitis c Virus  Inflammatory Response  Rna-dependent Rna Polymerase  
Celastrol inhibits lung cancer growth by triggering histone acetylation and acting synergically with HDAC inhibitors Journal article
Chen, Geer, Zhu, Xiaoyu, Li, Jiaqi, Zhang, Yao, Wang, Xiaoxuan, Zhang, Ren, Qin, Xinchen, Chen, Xi, Wang, Junyi, Liao, Weilin, Wu, Zongjin, Lu, Lu, Wu, Weiyu, Yu, Haijie, Ma, Lijuan. Celastrol inhibits lung cancer growth by triggering histone acetylation and acting synergically with HDAC inhibitors[J]. Pharmacological Research, 2022, 185.
Authors:  Chen, Geer;  Zhu, Xiaoyu;  Li, Jiaqi;  Zhang, Yao;  Wang, Xiaoxuan; et al.
Favorite | TC[WOS]:16 TC[Scopus]:17  IF:9.1/9.0 | Submit date：2023/01/31
Acetylation  Anacardic ACid (Pubchem Cid: 167551)  C646 (Pubchem Cid: 1285941)  Celastrol  Celastrol (Pubchem Cid: 122724)  Ci994 (Pubchem Cid: 2746)  Hdac  Histone Modification  Lung Cancer  Mc1568 (Pubchem Cid: 71311876)  Ms275 (Pubchem Cid: 4261)  Nu9056 (Pubchem Cid: 72201043)  Saha (Pubchem Cid: 5311)  
Antimalarial and antitumour activities of the steroidal quinone-methide celastrol and its combinations with artemiside, artemisone and methylene blue Journal article
Ng, Jerome P.L., Han, Yu, Yang, Li Jun, Birkholtz, Lyn Marie, Coertzen, Dina, Wong, Ho Ning, Haynes, Richard K., Coghi, Paolo, Wong, Vincent Kam Wai. Antimalarial and antitumour activities of the steroidal quinone-methide celastrol and its combinations with artemiside, artemisone and methylene blue[J]. Frontiers in Pharmacology, 2022, 13.
Authors:  Ng, Jerome P.L.;  Han, Yu;  Yang, Li Jun;  Birkholtz, Lyn Marie;  Coertzen, Dina; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:4.4/5.0 | Submit date：2023/01/30
Artemisinin  Artemisone  Cancer  Celastrol  Malaria  Redox Drug  Synergism  
Enhanced uptake and anti-maturation effect of celastrol-loaded mannosylated liposomes on dendritic cells for psoriasis treatment Journal article
Xi, Long, Lin, Zibei, Qiu, Fen, Chen, Shaokui, Li, Ping, Chen, Xin, Wang, Zhenping, Zheng, Ying. Enhanced uptake and anti-maturation effect of celastrol-loaded mannosylated liposomes on dendritic cells for psoriasis treatment[J]. Acta Pharmaceutica Sinica B, 2022, 12(1), 339-352.
Authors:  Xi, Long;  Lin, Zibei;  Qiu, Fen;  Chen, Shaokui;  Li, Ping; et al.
Favorite | TC[WOS]:48 TC[Scopus]:50  IF:14.7/14.1 | Submit date：2022/02/21
Anti-maturation  Celastrol  Dendritic Cells  Inflammation  Liposome  Mannose  Microneedle  Psoriasis  
Celastrol induces ferroptosis in activated HSCs to ameliorate hepatic fibrosis via targeting peroxiredoxins and HO-1 Journal article
Piao Luo, Dandan Liu, Qian Zhang, Fan Yang, Yin-Kwan Wong, Fei Xia, Junzhe Zhang, Jiayun Chen, Ya Tian, Chuanbin Yang, Lingyun Dai, Han-Ming Shen, Jigang Wang. Celastrol induces ferroptosis in activated HSCs to ameliorate hepatic fibrosis via targeting peroxiredoxins and HO-1[J]. Acta Pharmaceutica Sinica B, 2021, 12(5), 2300-2314.
Authors:  Piao Luo;  Dandan Liu;  Qian Zhang;  Fan Yang;  Yin-Kwan Wong; et al.
Favorite | TC[WOS]:132 TC[Scopus]:147  IF:14.7/14.1 | Submit date：2022/05/17
Abpp  Anti-oxidant  Celastrol  Ferroptosis  Hepatic Fibrosis  Ho-1  Peroxiredoxin  Reactive Oxygen Species  
Celastrol niosome hydrogel has anti-inflammatory effect on skin keratinocytes and circulation without systemic drug exposure in psoriasis mice Journal article
Qiu, Fen, Xi, Long, Chen, Shengshuang, Zhao, Yonghua, Wang, Zhenping, Zheng, Ying. Celastrol niosome hydrogel has anti-inflammatory effect on skin keratinocytes and circulation without systemic drug exposure in psoriasis mice[J]. International Journal of Nanomedicine, 2021, 16, 6171-6182.
Authors:  Qiu, Fen;  Xi, Long;  Chen, Shengshuang;  Zhao, Yonghua;  Wang, Zhenping; et al.
Adobe PDF | Favorite | TC[WOS]:14 TC[Scopus]:17 | Submit date：2022/05/13
Celastrol Niosome  Keratinocytes  Pharmacokinetics  Psoriasis  Topical Delivery  
Celastrol niosome hydrogel has anti-inflammatory effect on skin keratinocytes and circulation without systemic drug exposure in psoriasis mice. Journal article
Fen Qiu, Long Xi, Shengshuang Chen, Yonghua Zhao, Zhenping Wang, Ying Zheng. Celastrol niosome hydrogel has anti-inflammatory effect on skin keratinocytes and circulation without systemic drug exposure in psoriasis mice.[J]. International Journal of Nanomedicine, 2021, 16, 6171.
Authors:  Fen Qiu;  Long Xi;  Shengshuang Chen;  Yonghua Zhao;  Zhenping Wang; et al.
Favorite | TC[WOS]:14 TC[Scopus]:17  IF:6.6/7.5 | Submit date：2023/03/10
Celastrol Niosome  Keratinocytes  Pharmacokinetics  Psoriasis  Topical Delivery  
Loading of water-insoluble celastrol into niosome hydrogels for improved topical permeation and anti-psoriasis activity Journal article
Shikang Meng, Lin Sun, Lun Wang, Zibei Lin, Zeyu Liu, Long Xi, Zhenping Wang, Ying Zheng. Loading of water-insoluble celastrol into niosome hydrogels for improved topical permeation and anti-psoriasis activity[J]. COLLOIDS AND SURFACES B-BIOINTERFACES, 2019, 182.
Authors:  Shikang Meng;  Lin Sun;  Lun Wang;  Zibei Lin;  Zeyu Liu; et al.
Favorite | TC[WOS]:73 TC[Scopus]:85  IF:5.4/5.1 | Submit date：2020/04/08
Celastrol  Niosomes  Psoriasis  Topical Permeation