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Variability in SOD1-associated amyotrophic lateral sclerosis: geographic patterns, clinical heterogeneity, molecular alterations, and therapeutic implications
Journal article
Huang, Miaodan, Liu, Yong U., Yao, Xiaoli, Qin, Dajiang, Su, Huanxing. Variability in SOD1-associated amyotrophic lateral sclerosis: geographic patterns, clinical heterogeneity, molecular alterations, and therapeutic implications[J]. Translational Neurodegeneration, 2024, 13(1).
Authors:
Huang, Miaodan
;
Liu, Yong U.
;
Yao, Xiaoli
;
Qin, Dajiang
;
Su, Huanxing
Favorite
|
TC[WOS]:
2
TC[Scopus]:
3
IF:
10.8
/
11.6
|
Submit date:2024/09/03
Amyotrophic lateral sclerosis
Genetic therapy
Genotype
Geographic pattern
SOD1 variants
Variability in SOD1-associated amyotrophic lateral sclerosis: geographic patterns, clinical heterogeneity, molecular alterations, and therapeutic implications
Review article
2024
Authors:
Huang, Miaodan
;
Liu, Yong U.
;
Yao, Xiaoli
;
Qin, Dajiang
;
Su, Huanxing
Favorite
|
TC[WOS]:
2
TC[Scopus]:
3
IF:
10.8
/
11.6
|
Submit date:2024/07/04
Amyotrophic Lateral Sclerosis
Genetic Therapy
Genotype
Geographic Pattern
Sod1 Variants
DIAPH3 condensates formed by liquid-liquid phase separation act as a regulatory hub for stress-induced actin cytoskeleton remodeling
Journal article
Ke Zhang, Miaodan Huang, Ang Li, Jing Wen, Lingli Yan, Yunhao Li,, Liman Guo, Kumaran Satyanarayanan Senthil, Yangyang Zhou, Guobing Chen, Yong Liu, Xiaofei Zhang, Xiaoli Yao, Dajiang Qin, Huanxing Su. DIAPH3 condensates formed by liquid-liquid phase separation act as a regulatory hub for stress-induced actin cytoskeleton remodeling[J]. Cell Reports, 2023, 42(1), 111986.
Authors:
Ke Zhang
;
Miaodan Huang
;
Ang Li
;
Jing Wen
;
Lingli Yan
; et al.
Favorite
|
TC[WOS]:
9
TC[Scopus]:
10
IF:
7.5
/
8.5
|
Submit date:2023/02/08
Actin Filaments, f-Actin
Actin Remodeling
Cp: Cell Biology
D-granules
Diaphanous-related Formin 3, Diaph3
Filopodia
Liquid-liquid Phase Separation, Llps
Protein Condensates
Stress Assembly
Investigating the Dynamic Binding Behavior of PMX53 Cooperating with Allosteric Antagonist NDT9513727 to C5a Anaphylatoxin Chemotactic Receptor 1 through Gaussian Accelerated Molecular Dynamics and Free-Energy Perturbation Simulations
Journal article
Xiaoli, An, Yuzhen, Niu, Qiong, Yang, Yang, Lei, Yao, Xiaojun, Bing, Zhitong. Investigating the Dynamic Binding Behavior of PMX53 Cooperating with Allosteric Antagonist NDT9513727 to C5a Anaphylatoxin Chemotactic Receptor 1 through Gaussian Accelerated Molecular Dynamics and Free-Energy Perturbation Simulations[J]. ACS Chemical Neuroscience, 2022, 13(23), 3502-3511.
Authors:
Xiaoli, An
;
Yuzhen, Niu
;
Qiong, Yang
;
Yang, Lei
;
Yao, Xiaojun
; et al.
Favorite
|
TC[WOS]:
4
TC[Scopus]:
4
IF:
4.1
/
4.3
|
Submit date:2023/01/30
C5ar1
Free-energy Perturbation (Fep)
Gaussian Accelerated Molecular Dynamics (Gamd) Simulation
Ndt9513727
Pmx53
Key Molecules and Pathways Underlying Sporadic Amyotrophic Lateral Sclerosis: Integrated Analysis on Gene Expression Profiles of Motor Neurons
Journal article
Lin,Jianing, Huang,Pian, Chen,Weineng, Ye,Chenghui, Su,Huanxing, Yao,Xiaoli. Key Molecules and Pathways Underlying Sporadic Amyotrophic Lateral Sclerosis: Integrated Analysis on Gene Expression Profiles of Motor Neurons[J]. Frontiers in Genetics, 2020, 11, 578143.
Authors:
Lin,Jianing
;
Huang,Pian
;
Chen,Weineng
;
Ye,Chenghui
;
Su,Huanxing
; et al.
Favorite
|
TC[WOS]:
10
TC[Scopus]:
10
IF:
2.8
/
3.3
|
Submit date:2021/03/01
Bioinformatics Analysis
Fn1 Gene
Gene Expression Profiles
Motor Neurons
Sporadic Amyotrophic Lateral Sclerosis
A Chromosome-Level Genome Assembly of Dendrobium Huoshanense Using Long Reads and Hi-C Data
Journal article
Han,Bangxing, Jing,Yi, Dai,Jun, Zheng,Tao, Gu,Fangli, Zhao,Qun, Zhu,Fucheng, Song,Xiangwen, Deng,Hui, Wei,Peipei, Song,Cheng, Liu,Dong, Jiang,Xueping, Wang,Fang, Chen,Yanjun, Sun,Chuanbo, Yao,Houjun, Zhang,Li, Chen,Naidong, Chen,Shaotong, Li,Xiaoli, Wei,Yuan, Ouyang,Zhen, Yan,Hui, Lu,Jiangjie, Wang,Huizhong, Guo,Lanping, Kong,Lingdong, Zhao,Jing, Li,Shaoping, Luo,Lifen, Kristiansen,Karsten, Feng,Zhan, Sun,Silong, Chen,Cunwu, Yue,Zhen, Chen,Naifu. A Chromosome-Level Genome Assembly of Dendrobium Huoshanense Using Long Reads and Hi-C Data[J]. Genome biology and evolution, 2020, 12(12), 2486-2490.
Authors:
Han,Bangxing
;
Jing,Yi
;
Dai,Jun
;
Zheng,Tao
;
Gu,Fangli
; et al.
Favorite
|
TC[WOS]:
30
TC[Scopus]:
37
IF:
3.2
/
3.2
|
Submit date:2021/03/01
Annotation
De Novo Assembly
Genome
Hi-c Assembly
Orchid
Fish oil protects the blood-brain barrier integrity in a mouse model of Alzheimer's disease
Journal article
Xie,Youna, Yan,Lingli, Zeng,Haitao, Chen,Weineng, Lu,Jia Hong, Wan,Jian Bo, Su,Huanxing, Yao,Xiaoli. Fish oil protects the blood-brain barrier integrity in a mouse model of Alzheimer's disease[J]. Chinese Medicine, 2020, 15(1), 29.
Authors:
Xie,Youna
;
Yan,Lingli
;
Zeng,Haitao
;
Chen,Weineng
;
Lu,Jia Hong
; et al.
Favorite
|
TC[WOS]:
13
TC[Scopus]:
13
IF:
5.3
/
5.5
|
Submit date:2021/03/01
Amyloid Beta
Aβ-degrading Enzymes
Neuroinflammation
Nf-κb
Omega-3 Polyunsaturated Fatty Acids
Omega-3 polyunsaturated fatty acids promote brain-to-blood clearance of β-Amyloid in a mouse model with Alzheimer's disease
Journal article
Yan,Lingli, Xie,Youna, Satyanarayanan,Senthil Kumaran, Zeng,Haitao, Liu,Qiang, Huang,Miaodan, Ma,Yuemeng, Wan,Jian Bo, Yao,Xiaoli, Su,Kuan Pin, Su,Huanxing. Omega-3 polyunsaturated fatty acids promote brain-to-blood clearance of β-Amyloid in a mouse model with Alzheimer's disease[J]. BRAIN BEHAVIOR AND IMMUNITY, 2020, 85, 35-45.
Authors:
Yan,Lingli
;
Xie,Youna
;
Satyanarayanan,Senthil Kumaran
;
Zeng,Haitao
;
Liu,Qiang
; et al.
Favorite
|
TC[WOS]:
30
TC[Scopus]:
39
IF:
8.8
/
9.8
|
Submit date:2021/03/01
Alzheimer's Disease
Beta-amyloid
Low-density LipoProtein Receptor-related Protein 1
Neuroinflammation
Omega-3 Polyunsaturated Fatty Acids
Experimental alcoholism primes structural and functional impairment of the glymphatic pathway
Journal article
Liu,Qiang, Yan,Lingli, Huang,Miaodan, Zeng,Haitao, Satyanarayanan,Senthil Kumaran, Shi,Zhe, Chen,Dingbang, Lu,Jia Hong, Pei,Zhong, Yao,Xiaoli, Su,Huanxing. Experimental alcoholism primes structural and functional impairment of the glymphatic pathway[J]. BRAIN BEHAVIOR AND IMMUNITY, 2020, 85, 106-119.
Authors:
Liu,Qiang
;
Yan,Lingli
;
Huang,Miaodan
;
Zeng,Haitao
;
Satyanarayanan,Senthil Kumaran
; et al.
Favorite
|
TC[WOS]:
22
TC[Scopus]:
24
IF:
8.8
/
9.8
|
Submit date:2021/03/01
Alcoholism
Aqp4 Polarization
Aβ Clearance
Csf-isf Exchange
Azoramide protects iPSC-derived dopaminergic neurons with PLA2G6 D331Y mutation through restoring ER function and CREB signaling
Journal article
Ke,Minjing, Chong,Cheong Meng, Zeng,Haitao, Huang,Miaodan, Huang,Zhijian, Zhang,Ke, Cen,Xiaotong, Lu,Jia Hong, Yao,Xiaoli, Qin,Dajiang, Su,Huanxing. Azoramide protects iPSC-derived dopaminergic neurons with PLA2G6 D331Y mutation through restoring ER function and CREB signaling[J]. Cell Death and Disease, 2020, 11(2), 130.
Authors:
Ke,Minjing
;
Chong,Cheong Meng
;
Zeng,Haitao
;
Huang,Miaodan
;
Huang,Zhijian
; et al.
Favorite
|
TC[WOS]:
21
TC[Scopus]:
21
IF:
8.1
/
8.6
|
Submit date:2021/03/01