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Tetramethylpyrazine nitrone exerts neuroprotection via activation of PGC-1α/Nrf2 pathway in Parkinson's disease models Journal article
Guo, Baojian, Zheng, Chengyou, Cao, Jie, Luo, Fangcheng, Li, Haitao, Hu, Shengquan, Mingyuan Lee, Simon, Yang, Xifei, Zhang, Gaoxiao, Zhang, Zaijun, Sun, Yewei, Wang, Yuqiang. Tetramethylpyrazine nitrone exerts neuroprotection via activation of PGC-1α/Nrf2 pathway in Parkinson's disease models[J]. Journal of Advanced Research, 2024, 64, 195-211.
Authors:  Guo, Baojian;  Zheng, Chengyou;  Cao, Jie;  Luo, Fangcheng;  Li, Haitao; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:11.4/11.0 | Submit date：2024/02/22
Nuclear Factor Erythroid-2-related Factor 2  Parkinson's Disease  Peroxisome Proliferator-activated Receptor γ Co-activator 1α  Tetramethylpyrazine Nitrone  
Tetramethylpyrazine Nitrone (TBN) Reduces Amyloid β Deposition in Alzheimer’s Disease Models by Modulating APP Expression, BACE1 Activity, and Autophagy Pathways Journal article
Zhou, Xinhua, Zhu, Zeyu, Kuang, Shaoming, Huang, Kaipeng, Li, Yueping, Wang, Yuqiang, Chen, Haiyun, Hoi, Maggie Pui Man, Xu, Benhong, Yang, Xifei, Zhang, Zaijun. Tetramethylpyrazine Nitrone (TBN) Reduces Amyloid β Deposition in Alzheimer’s Disease Models by Modulating APP Expression, BACE1 Activity, and Autophagy Pathways[J]. Pharmaceuticals, 2024, 17(8), 1005.
Authors:  Zhou, Xinhua;  Zhu, Zeyu;  Kuang, Shaoming;  Huang, Kaipeng;  Li, Yueping; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.3/4.6 | Submit date：2024/10/10
Amyloid Precursor Protein  Amyloid β  Microrna  
Tetramethylpyrazine Nitrone Promotes the Clearance of Alpha-Synuclein via Nrf2-Mediated Ubiquitin–Proteasome System Activation Journal article
Guo, Baojian, Zheng, Chengyou, Cao, Jie, Qiu, Xiaoling, Luo, Fangcheng, Li, Haitao, Lee, Simon Mingyuan, Yang, Xifei, Zhang, Gaoxiao, Sun, Yewei, Zhang, Zaijun, Wang, Yuqiang. Tetramethylpyrazine Nitrone Promotes the Clearance of Alpha-Synuclein via Nrf2-Mediated Ubiquitin–Proteasome System Activation[J]. NeuroMolecular Medicine, 2024, 26(1), 9.
Authors:  Guo, Baojian;  Zheng, Chengyou;  Cao, Jie;  Qiu, Xiaoling;  Luo, Fangcheng; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:3.3/3.6 | Submit date：2024/05/16
Nuclear Factor Erythroid-2-related Factor 2  Parkinson’s Disease  Peroxisome Proliferator-activated Receptor γ Co-activator 1α  Tetramethylpyrazine Nitrone  Ubiquitin–proteasome System  Α-synuclein  
Evaluation of therapeutic effects of tetramethylpyrazine nitrone in Alzheimer’s disease mouse model and proteomics analysis Journal article
Xinhua Zhou, Kaipeng Huang, Yuqiang Wang, Zaijun Zhang, Yingying Liu, Qinghua Hou, Xifei Yang, Maggie Pui Man Hoi. Evaluation of therapeutic effects of tetramethylpyrazine nitrone in Alzheimer’s disease mouse model and proteomics analysis[J]. Frontiers in Pharmacology, 2023, 14, 1082602.
Authors:  Xinhua Zhou;  Kaipeng Huang;  Yuqiang Wang;  Zaijun Zhang;  Yingying Liu; et al.
Favorite | TC[WOS]:10 TC[Scopus]:10  IF:4.4/5.0 | Submit date：2023/08/03
Alhzheimer Disease  Amyloid Beta  Pink1  Proteomic Analysis  Tetramethylpyrazine Nitrone  
Natural Dietary Compound Xanthohumol Regulates the Gut Microbiota and Its Metabolic Profile in a Mouse Model of Alzheimer’s Disease Journal article
Liu, Wei, He, Kaiwu, Wu, Desheng, Zhou, Li, Li, Guowei, Lin, Zequn, Yang, Xifei, Liu, Jianjun, Hoi, Maggie Pui Man. Natural Dietary Compound Xanthohumol Regulates the Gut Microbiota and Its Metabolic Profile in a Mouse Model of Alzheimer’s Disease[J]. Molecules, 2022, 27(4), 1281.
Authors:  Liu, Wei;  He, Kaiwu;  Wu, Desheng;  Zhou, Li;  Li, Guowei; et al.
Favorite | TC[WOS]:12 TC[Scopus]:12  IF:4.2/4.6 | Submit date：2022/03/04
16s Rdna Sequencing  Alzheimer’s Disease  Gut Microbiota  Microbial Diversity  Xanthohumol  
Therapeutic efficacy of novel memantine nitrate MN-08 in animal models of Alzheimer’s disease Journal article
Wu, Liangmiao, Zhou, Xinhua, Cao, Yiwan, Mak, Shing Hung, Zha, Ling, Li, Ning, Su, Zhiyang, Han, Yifan, Wang, Yuqiang, Man Hoi, Maggie Pui, Sun, Yewei, Zhang, Gaoxiao, Zhang, Zaijun, Yang, Xifei. Therapeutic efficacy of novel memantine nitrate MN-08 in animal models of Alzheimer’s disease[J]. AGING CELL, 2021, 20(6), e13371.
Authors:  Wu, Liangmiao;  Zhou, Xinhua;  Cao, Yiwan;  Mak, Shing Hung;  Zha, Ling; et al.
Favorite | TC[WOS]:14 TC[Scopus]:15  IF:8.0/9.7 | Submit date：2021/12/08
Alzheimer’s Disease  Cognitive Deficits  Memantine Nitrate  N-methyl-d-aspartate (Nmda) Receptors  Nitric Oxide  
Memantine improves cognitive function and alters hippocampal and cortical proteome in triple transgenic mouse model of Alzheimer’s disease Journal article
Zhou,Xinhua, Wang,Liang, Xiao,Wei, Su,Zhiyang, Zheng,Chengyou, Zhang,Zaijun, Wang,Yuqiang, Xu,Benhong, Yang,Xifei, Hoi,Maggie Pui Man. Memantine improves cognitive function and alters hippocampal and cortical proteome in triple transgenic mouse model of Alzheimer’s disease[J]. Experimental Neurobiology, 2019, 28(3), 390-403.
Authors:  Zhou,Xinhua;  Wang,Liang;  Xiao,Wei;  Su,Zhiyang;  Zheng,Chengyou; et al.
Favorite | TC[WOS]:24 TC[Scopus]:27  IF:1.8/2.8 | Submit date：2021/03/01
Alzheimer’s Disease (Ad)  Mark2  Memantine  Proteomic  
Hippocampal Proteomic Alteration in Triple Transgenic Mouse Model of Alzheimer's Disease and Implication of PINK 1 Regulation in Donepezil Treatment Journal article
Zhou, Xinhua, Xiao, Wei, Su, Zhiyang, Cheng, Jiehong, Zheng, Chengyou, Zhang, Zaijun, Wang, Yuqiang, Wang, Liang, Xu, Benhong, Li, Shupen, Yang, Xifei, Pui Man Hoi, Maggie. Hippocampal Proteomic Alteration in Triple Transgenic Mouse Model of Alzheimer's Disease and Implication of PINK 1 Regulation in Donepezil Treatment[J]. Journal of Proteome Research, 2019, 18(4), 1542-1552.
Authors:  Zhou, Xinhua;  Xiao, Wei;  Su, Zhiyang;  Cheng, Jiehong;  Zheng, Chengyou; et al.
Favorite | TC[WOS]:33 TC[Scopus]:34  IF:3.8/4.1 | Submit date：2022/04/15
Alzheimer's Disease (Ad)  Amyloid Beta (Aβ)  Donepezil  Pink 1  Proteomics  
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
Guo, Baojian, Hu, Shengquan, Zheng, Chengyou, Wang, Hongyu, Luo, Fangcheng, Li, Haitao, Cui, Wei, Yang, Xifei, Cui, Guozhen, Mak, Shinghung, Choi, Tony Chung-Lit, Ma, Edmond Dik-Lung, Wang, Yuqiang, Lee, Simon Ming Yuen, Zhang, Zaijun, Han, Yifan. Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B[J]. NEUROPHARMACOLOGY, 2017, 126, 12-24.
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng; et al.
View | Adobe PDF | Favorite | TC[WOS]:18 TC[Scopus]:20  IF:4.6/4.5 | Submit date：2018/10/31
Parkinson's Disease  Su4312  Neuroprotection  Myocyte Enhancer Factor 2d  Monoamine Oxidase-b