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Small molecule deoxynyboquinone triggers alkylation and ubiquitination of Keap1 at Cys489 on Kelch domain for Nrf2 activation and inflammatory therapy Journal article
Linghu, Ke-Gang, Zhang, Tian, Zhang, Guang-Tao, Lv, Peng, Zhang, Wenjun, Zhao, Guanding, Xiong, Shihong, Zhao, Mingming, Chen, Meiwan, HU YUANJIA, Zhang, Changsheng, Yu, Hua. Small molecule deoxynyboquinone triggers alkylation and ubiquitination of Keap1 at Cys489 on Kelch domain for Nrf2 activation and inflammatory therapy[J]. Journal of Pharmaceutical Analysis, 2024, 14(3), 401-415.
Authors:  Linghu, Ke-Gang;  Zhang, Tian;  Zhang, Guang-Tao;  Lv, Peng;  Zhang, Wenjun; et al.
Favorite | TC[WOS]:6 TC[Scopus]:9  IF:6.1/6.8 | Submit date：2024/01/02
Deoxynyboquinone  Anti-inflammation  Target  Keap1/nrf2  Alkylation  Ubiquitination  
The Role of Solution Aggregation Property toward High-Efficiency Non-Fullerene Organic Photovoltaic Cells Journal article
Xu, Lei, Li, Sunsun, Zhao, Wenchao, Xiong, Yaomeng, Yu, Jinfeng, Qin, Jinzhao, Wang, Gang, Zhang, Rui, Zhang, Tao, Mu, Zhen, Zhao, Jingjing, Zhang, Yuyang, Zhang, Shaoqing, Kuvondikov, Vakhobjon, Zakhidov, Erkin, Peng, Qiming, Wang, Nana, Xing, Guichuan, Gao, Feng, Hou, Jianhui, Huang, Wei, Wang, Jianpu. The Role of Solution Aggregation Property toward High-Efficiency Non-Fullerene Organic Photovoltaic Cells[J]. Advanced Materials, 2024.
Authors:  Xu, Lei;  Li, Sunsun;  Zhao, Wenchao;  Xiong, Yaomeng;  Yu, Jinfeng; et al.
Favorite | TC[WOS]:9 TC[Scopus]:6  IF:27.4/30.2 | Submit date：2024/05/16
Aggregation Kinetics  Film Morphology  Non-fullerene  Organic Photovoltaic Cells  Solution-aggregation Effects  
Leocarpinolide B Attenuates Collagen Type II-Induced Arthritis by Inhibiting DNA Binding Activity of NF-κB Journal article
Linghu, Ke Gang, Zhao, Guan Ding, Zhang, Dai Yan, Xiong, Shi Hang, Wu, Guo Ping, Shen, Li Yu, Cui, Wen Qing, Zhang, Tian, Hu, Yuan Jia, Guo, Bing, Shen, Xiang Chun, Yu, Hua. Leocarpinolide B Attenuates Collagen Type II-Induced Arthritis by Inhibiting DNA Binding Activity of NF-κB[J]. Molecules (Basel, Switzerland), 2023, 28(10), 4241.
Authors:  Linghu, Ke Gang;  Zhao, Guan Ding;  Zhang, Dai Yan;  Xiong, Shi Hang;  Wu, Guo Ping; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:4.2/4.6 | Submit date：2023/06/05
Leocarpinolide b  Nf-κb P65  Rheumatoid Arthritis  Sesquiterpene Lactone  Synovitis  
The “whole ingredients extract” of Astragali Radix improves the symptoms of dextran sulfate sodium-induced ulcerative colitis in mice through systemic immunomodulation Journal article
Linghu, Ke Gang, Ma, Qiushuo, Xiong, Shi Hang, Zhao, Mingming, Chen, Qiling, Xu, Wen, Chen, Meiwan, Zhang, Jian Ye, Hu, Yuanjia, Xu, Wei, Yu, Hua. The “whole ingredients extract” of Astragali Radix improves the symptoms of dextran sulfate sodium-induced ulcerative colitis in mice through systemic immunomodulation[J]. Chinese Medicine (United Kingdom), 2022, 17(1), 109.
Authors:  Linghu, Ke Gang;  Ma, Qiushuo;  Xiong, Shi Hang;  Zhao, Mingming;  Chen, Qiling; et al.
Favorite | TC[WOS]:3 TC[Scopus]:4  IF:5.3/5.5 | Submit date：2023/01/30
Astragali Radix  Whole Ingredients Extract  Immunomodulation  Ulcerative Colitis  
Anti-inflammatory/anti-oxidant properties and the UPLC-QTOF/MS-based metabolomics discrimination of three yellow camellia species Journal article
Zhao, Mingming, Linghu, Ke-Gang, Xiao, Linxuan, Hua, Tianyi, Zhao, Guanding, Chen, Qiling, Xiong, Shihang, Shen, Liyu, Yu, Jinyu, Hou, Xiaotao, Hao, Erwei, Du, Zhengcai, Deng, Jiagang, Bai, Gang, Chen, Xiaojia, Li, Ling, Li, Peng, Yu, Hua. Anti-inflammatory/anti-oxidant properties and the UPLC-QTOF/MS-based metabolomics discrimination of three yellow camellia species[J]. Food Research International, 2022, 160, 111628.
Authors:  Zhao, Mingming;  Linghu, Ke-Gang;  Xiao, Linxuan;  Hua, Tianyi;  Zhao, Guanding; et al.
Favorite | TC[WOS]:12 TC[Scopus]:11  IF:7.0/7.4 | Submit date：2022/08/18
Yellow Camellias  Discrimination  Metabolomics  Fingerprint  Anti -inflammation  Anti -oxidant  
Brij-functionalized chitosan nanocarrier system enhances the intestinal permeability of P-glycoprotein substrate-like drugs Journal article
Xiong, Wei, Xiong, Shi Hang, Chen, Qi Ling, Linghu, Ke Gang, Zhao, Guan Ding, Chu, John M.T., Wong, Gordon T.C., Li, Juan, Hu, Yuan Jia, Wang, Yi Tao, Yu, Hua. Brij-functionalized chitosan nanocarrier system enhances the intestinal permeability of P-glycoprotein substrate-like drugs[J]. Carbohydrate Polymers, 2021, 266.
Authors:  Xiong, Wei;  Xiong, Shi Hang;  Chen, Qi Ling;  Linghu, Ke Gang;  Zhao, Guan Ding; et al.
Favorite | TC[WOS]:15 TC[Scopus]:18  IF:10.7/10.2 | Submit date：2021/09/13
Berberine  Brij-grafted-chitosan  Diabetic Kidney Disease  Oral Nanocarrier  P-glycoprotein  
Botany, traditional use, phytochemistry, pharmacology and toxicology of Sigesbeckiae Herba (Xixiancao): a review Review article
2021
Authors:  Tao,Hong Xun;  Zhao,Guan Ding;  Linghu,Ke Gang;  Xiong,Wei;  Sang,Wei; et al.
Favorite | TC[WOS]:10 TC[Scopus]:9  IF:7.3/7.9 | Submit date：2021/03/02
Sigesbeckiae Herba  Traditional Use  Phytochemistry  Pharmacology  Toxicology  
Sustained tnf-α stimulation leads to transcriptional memory that greatly enhances signal sensitivity and robustness Journal article
Zhao,Zuodong, Zhang,Zhuqiang, Li,Jingjing, Dong,Qiang, Xiong,Jun, Li,Yingfeng, Lan,Mengying, Li,Gang, Zhu,Bing. Sustained tnf-α stimulation leads to transcriptional memory that greatly enhances signal sensitivity and robustness[J]. eLife, 2020, 9, e61965.
Authors:  Zhao,Zuodong;  Zhang,Zhuqiang;  Li,Jingjing;  Dong,Qiang;  Xiong,Jun; et al.
Favorite | TC[WOS]:26 TC[Scopus]:26  IF:6.4/7.2 | Submit date：2021/03/04
Sigesbeckia orientalis L. Extract Alleviated the Collagen Type II–Induced Arthritis Through Inhibiting Multi-Target–Mediated Synovial Hyperplasia and Inflammation Journal article
Linghu,Ke Gang, Xiong,Shi Hang, Zhao,Guan Ding, Zhang,Tian, Xiong,Wei, Zhao,Mingming, Shen,Xiang Chun, Xu,Wei, Bian,Zhaoxiang, Wang,Yitao, Yu,Hua. Sigesbeckia orientalis L. Extract Alleviated the Collagen Type II–Induced Arthritis Through Inhibiting Multi-Target–Mediated Synovial Hyperplasia and Inflammation[J]. Frontiers in Pharmacology, 2020, 11, 547913.
Authors:  Linghu,Ke Gang;  Xiong,Shi Hang;  Zhao,Guan Ding;  Zhang,Tian;  Xiong,Wei; et al.
Favorite | TC[WOS]:16 TC[Scopus]:15  IF:4.4/5.0 | Submit date：2021/03/02
Inflammation  Mh7a  Rheumatoid Arthritis  Sigesbeckia Orientalisl  Sw982  Synovial Hyperplasia  
Sigesbeckia glabrescens Makino extract attenuated the collagen-induced arthritis through inhibiting the synovial hyperplasia and inflammation Journal article
Ma,Qiu Shuo, Linghu,Ke Gang, Zhang,Tian, Zhao,Guan Ding, Xiong,Wei, Xiong,Shi Hang, Zhao,Mingming, Xu,Wei, Yu,Juan, Yu,Hua. Sigesbeckia glabrescens Makino extract attenuated the collagen-induced arthritis through inhibiting the synovial hyperplasia and inflammation[J]. Chinese Medicine, 2020, 15(1), 91.
Authors:  Ma,Qiu Shuo;  Linghu,Ke Gang;  Zhang,Tian;  Zhao,Guan Ding;  Xiong,Wei; et al.
Favorite | TC[WOS]:2 TC[Scopus]:3  IF:5.3/5.5 | Submit date：2021/03/02
Inflammation  Nuclear Transcription Factor-kappa b  Rheumnnatoid Arthritis  Sigesbeckia Glabrescens Makino  Sw982  Synovial Hyperplasia