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Discovery of potent LRRK2 inhibitors by ensemble virtual screening strategy and bioactivity evaluation
Journal article
Gong, Xiaoqing, Li, Shuli, Huang, Junli, Tan, Shuoyan, Zhang, Qianqian, Tian, Yanan, Li, Qin, Wang, Lingling, Tong, Henry H.Y., Yao, Xiaojun, Chen, Chunxia, Lee, Simon Ming Yuen, Liu, Huanxiang. Discovery of potent LRRK2 inhibitors by ensemble virtual screening strategy and bioactivity evaluation[J]. European Journal of Medicinal Chemistry, 2024, 279, 116812.
Authors:
Gong, Xiaoqing
;
Li, Shuli
;
Huang, Junli
;
Tan, Shuoyan
;
Zhang, Qianqian
; et al.
Favorite
|
TC[WOS]:
0
TC[Scopus]:
0
IF:
6.0
/
6.1
|
Submit date:2024/10/10
Fingerprint
Lrrk2
Molecular Docking
Pharmacophore
Virtual Screening
Zebrafish
Variability in SOD1-associated amyotrophic lateral sclerosis: geographic patterns, clinical heterogeneity, molecular alterations, and therapeutic implications
Journal article
Huang, Miaodan, Liu, Yong U., Yao, Xiaoli, Qin, Dajiang, Su, Huanxing. Variability in SOD1-associated amyotrophic lateral sclerosis: geographic patterns, clinical heterogeneity, molecular alterations, and therapeutic implications[J]. Translational Neurodegeneration, 2024, 13(1).
Authors:
Huang, Miaodan
;
Liu, Yong U.
;
Yao, Xiaoli
;
Qin, Dajiang
;
Su, Huanxing
Favorite
|
TC[WOS]:
1
TC[Scopus]:
3
IF:
10.8
/
11.6
|
Submit date:2024/09/03
Amyotrophic lateral sclerosis
Genetic therapy
Genotype
Geographic pattern
SOD1 variants
Cytological analysis of flower development, insights into suitable growth area and genomic background: implications for Glehnia littoralis conservation and sustainable utilization
Journal article
An, Chang, Ye, Kangzhuo, Jiang, Runfa, Chen, Jiayi, Yao, Yixin, Lu, Lin, Cheng, Yan, Liu, Ruoyu, Liu, Xiaofen, Zhao, Heming, Qin, Yuan, Zheng, Ping. Cytological analysis of flower development, insights into suitable growth area and genomic background: implications for Glehnia littoralis conservation and sustainable utilization[J]. BMC plant biology, 2024, 24(1), 895.
Authors:
An, Chang
;
Ye, Kangzhuo
;
Jiang, Runfa
;
Chen, Jiayi
;
Yao, Yixin
; et al.
Favorite
|
TC[WOS]:
0
TC[Scopus]:
0
IF:
4.3
/
5.2
|
Submit date:2024/10/10
Glehnia Littoralis
Flower Development
Genomic Background
Suitable Growth Area
Evaluation of the anti-atherosclerotic effect for Allium macrostemon Bge. Polysaccharides and structural characterization of its a newly active fructan
Journal article
Lin, Pei, Wang, Qiqi, Wang, Qi, Chen, Jiayun, He, Liangliang, Qin, Zifei, Li, Shaoping, Han, Jingyan, Yao, Xinsheng, Yu, Yang, Yao, Zhihong. Evaluation of the anti-atherosclerotic effect for Allium macrostemon Bge. Polysaccharides and structural characterization of its a newly active fructan[J]. Carbohydrate Polymers, 2024, 340, 122289.
Authors:
Lin, Pei
;
Wang, Qiqi
;
Wang, Qi
;
Chen, Jiayun
;
He, Liangliang
; et al.
Favorite
|
TC[WOS]:
0
TC[Scopus]:
1
IF:
10.7
/
10.2
|
Submit date:2024/06/05
Allium Mcrostemon Bge.
Anti-atherosclerosis
Apoe−/− Mice
Foam Cell
Fructan
Polysaccharide
Schizophrenia-Like Behaviors Arising from Dysregulated Proline Metabolism Are Associated with Altered Neuronal Morphology and Function in Mice with Hippocampal PRODH Deficiency
Journal article
Yao, Yuxiao, Jin, Chenchen, Liao, Yilie, Huang, Xiang, Wei, Ziying, Zhang, Yahong, Li, Dongwei, Su, Huanxing, Han, Weiping, Qin, Dajiang. Schizophrenia-Like Behaviors Arising from Dysregulated Proline Metabolism Are Associated with Altered Neuronal Morphology and Function in Mice with Hippocampal PRODH Deficiency[J]. Aging and Disease, 2024, 15(4), 1952-1968.
Authors:
Yao, Yuxiao
;
Jin, Chenchen
;
Liao, Yilie
;
Huang, Xiang
;
Wei, Ziying
; et al.
Favorite
|
TC[WOS]:
1
TC[Scopus]:
1
IF:
7.0
/
7.1
|
Submit date:2024/09/03
Hippocampus
Metabolism
Neuron
Prodh
Proline
Schizophrenia
Variability in SOD1-associated amyotrophic lateral sclerosis: geographic patterns, clinical heterogeneity, molecular alterations, and therapeutic implications
Review article
2024
Authors:
Huang, Miaodan
;
Liu, Yong U.
;
Yao, Xiaoli
;
Qin, Dajiang
;
Su, Huanxing
Favorite
|
TC[WOS]:
1
TC[Scopus]:
3
IF:
10.8
/
11.6
|
Submit date:2024/07/04
Amyotrophic Lateral Sclerosis
Genetic Therapy
Genotype
Geographic Pattern
Sod1 Variants
DNA polymerase delta governs parental histone transfer to DNA replication lagging strand
Journal article
Tian, Congcong, Zhang, Qin, Jia, Jing, Zhou, Jiaqi, Zhang, Ziwei, Karri, Srinivasu, Jiang, Jiuhang, Dickinson, Quinn, Yao, Yuan, Tang, Xiaorong, Huang, Yuxin, Guo, Ting, He, Ziwei, Liu, Zheng, Gao, Yuan, Yang, Xinran, Wu, Yuchun, Chan, Kui Ming, Zhang, Daoqin, Han, Junhong, Yu, Chuanhe, Gan, Haiyun. DNA polymerase delta governs parental histone transfer to DNA replication lagging strand[J]. Proceedings of the National Academy of Sciences of the United States of America, 2024, 121(20), e2400610121.
Authors:
Tian, Congcong
;
Zhang, Qin
;
Jia, Jing
;
Zhou, Jiaqi
;
Zhang, Ziwei
; et al.
Favorite
|
TC[WOS]:
4
TC[Scopus]:
4
IF:
9.4
/
10.8
|
Submit date:2024/06/05
Dna Polymerase δ
Epigenetic Inheritance
Histone Chaperone
Parental Histone Transfer
Pol32
DeFi Auditing: Mechanisms, Effectiveness, and User Perceptions
Conference paper
Feng, Ding, Hitsch, Rupert, Qin, Kaihua, Gervais, Arthur, Wattenhofer, Roger, Yao, Yaxing, Wang, Ye. DeFi Auditing: Mechanisms, Effectiveness, and User Perceptions[C]:SPRINGER-VERLAG BERLINHEIDELBERGER PLATZ 3, D-14197 BERLIN, GERMANY, 2024, 320-336.
Authors:
Feng, Ding
;
Hitsch, Rupert
;
Qin, Kaihua
;
Gervais, Arthur
;
Wattenhofer, Roger
; et al.
Favorite
|
TC[WOS]:
0
TC[Scopus]:
0
|
Submit date:2024/05/16
Auditing
Blockchain
Decentralized Finance
Semantic Segmentation of Gastric Polyps in Endoscopic Images Based on Convolutional Neural Networks and Integrated Evaluation Approach
Journal article
Yan, Tao, Ye, Ying Qin, Wong, Pak Kin, Ren Hao, Wong, Chi Hong, Yao, Liang, Hu, Ying, Chan, Cheok I, Gao, Shan, Chan, Pui Pun. Semantic Segmentation of Gastric Polyps in Endoscopic Images Based on Convolutional Neural Networks and Integrated Evaluation Approach[J]. Bioengineering-BASEL, 2023, 10(7).
Authors:
Yan, Tao
;
Ye, Ying Qin
;
Wong, Pak Kin
;
Ren Hao
;
Wong, Chi Hong
; et al.
Favorite
|
TC[WOS]:
5
TC[Scopus]:
5
|
Submit date:2023/08/25
Gastric Polyps
Semantic Segmentation
Convolutional Neural Networks
Integrated Evaluation Approach
DIAPH3 condensates formed by liquid-liquid phase separation act as a regulatory hub for stress-induced actin cytoskeleton remodeling
Journal article
Ke Zhang, Miaodan Huang, Ang Li, Jing Wen, Lingli Yan, Yunhao Li,, Liman Guo, Kumaran Satyanarayanan Senthil, Yangyang Zhou, Guobing Chen, Yong Liu, Xiaofei Zhang, Xiaoli Yao, Dajiang Qin, Huanxing Su. DIAPH3 condensates formed by liquid-liquid phase separation act as a regulatory hub for stress-induced actin cytoskeleton remodeling[J]. Cell Reports, 2023, 42(1), 111986.
Authors:
Ke Zhang
;
Miaodan Huang
;
Ang Li
;
Jing Wen
;
Lingli Yan
; et al.
Favorite
|
TC[WOS]:
9
TC[Scopus]:
10
IF:
7.5
/
8.5
|
Submit date:2023/02/08
Actin Filaments, f-Actin
Actin Remodeling
Cp: Cell Biology
D-granules
Diaphanous-related Formin 3, Diaph3
Filopodia
Liquid-liquid Phase Separation, Llps
Protein Condensates
Stress Assembly