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Engineering hyaluronic acid-based nanoassemblies for monoclonal antibody delivery – design, characterization, and biological insights
Journal article
López-Estévez, Ana M., Zhang, Y., Medel, María, Arriaga, Iker, Sanjurjo, Lucía, Huck-Iriart, Cristian, Abrescia, Nicola G.A., Vicent, María J., Ouyang, Defang, Torres, Dolores, Alonso, María José. Engineering hyaluronic acid-based nanoassemblies for monoclonal antibody delivery – design, characterization, and biological insights[J]. Nano Research, 2024, 17(10), 9111-9125.
Authors:
López-Estévez, Ana M.
;
Zhang, Y.
;
Medel, María
;
Arriaga, Iker
;
Sanjurjo, Lucía
; et al.
Favorite
|
TC[WOS]:
0
TC[Scopus]:
1
IF:
9.5
/
9.0
|
Submit date:2024/08/05
Monoclonal Antibody
Nanoparticles
Hyaluronic Acid
Characterization
Particle Size
Computational Modeling
Modeling on in vivo disposition and cellular transportation of RNA lipid nanoparticles via quantum mechanics/physiologically-based pharmacokinetic approaches
Journal article
Wang, Wei, Deng, Shiwei, Lin, Jinzhong, Ouyang, Defang. Modeling on in vivo disposition and cellular transportation of RNA lipid nanoparticles via quantum mechanics/physiologically-based pharmacokinetic approaches[J]. Acta Pharmaceutica Sinica B, 2024, 14(10), 4591-4607.
Authors:
Wang, Wei
;
Deng, Shiwei
;
Lin, Jinzhong
;
Ouyang, Defang
Favorite
|
TC[WOS]:
0
TC[Scopus]:
0
IF:
14.7
/
14.1
|
Submit date:2024/09/03
Lipid Nanoparticle
Rna
Ionizable Lipid
In Vivo Transportation
Endosomal Escape
Metabolism
Quantum Mechanics
Physiologically-based Pharmacokinetics
Predicting Peptide Permeability Across Diverse Barriers: A Systematic Investigation
Journal article
Tan, Xiaorong, Liu, Qianhui, Fang, Yanpeng, Zhu, Yingli, Chen, Fei, Zeng, Wenbin, Ouyang, Defang, Dong, Jie. Predicting Peptide Permeability Across Diverse Barriers: A Systematic Investigation[J]. Molecular Pharmaceutics, 2024, 21(8), 4116-4127.
Authors:
Tan, Xiaorong
;
Liu, Qianhui
;
Fang, Yanpeng
;
Zhu, Yingli
;
Chen, Fei
; et al.
Favorite
|
TC[WOS]:
1
TC[Scopus]:
1
IF:
4.5
/
4.6
|
Submit date:2024/08/05
Cell Permeability
Drug Delivery
Graph Neural Network
Machine Learning
Peptide
Permeability Prediction
Introducing enzymatic cleavage features and transfer learning realizes accurate peptide half-life prediction across species and organs
Journal article
Tan, Xiaorong, Liu, Qianhui, Fang, Yanpeng, Yang, Sen, Chen, Fei, Wang, Jianmin, Ouyang, Defang, Dong, Jie, Zeng, Wenbin. Introducing enzymatic cleavage features and transfer learning realizes accurate peptide half-life prediction across species and organs[J]. Briefings in Bioinformatics, 2024, 25(4), bbae350.
Authors:
Tan, Xiaorong
;
Liu, Qianhui
;
Fang, Yanpeng
;
Yang, Sen
;
Chen, Fei
; et al.
Favorite
|
TC[WOS]:
1
TC[Scopus]:
1
IF:
6.8
/
7.9
|
Submit date:2024/08/05
Drug Design
Enzymatic Cleavage Features
Half-life
Machine Learning
Peptide Drugs
Transfer Learning
Self-Assembled Micelles Based on Ginsenoside Rg5 for the Targeted Treatment of PTX-Resistant Tumors
Journal article
Gao, Feiyan, Ma, Zhongyi, Luo, Xing, Wang, Yahua, Liu, Xinlong, Tang, Mei, Chen, Junyu, Tu, Liangxing, Ouyang, Defang, Zheng, Ji, Li, Chong. Self-Assembled Micelles Based on Ginsenoside Rg5 for the Targeted Treatment of PTX-Resistant Tumors[J]. Molecular Pharmaceutics, 2024, 21(7), 3502-3512.
Authors:
Gao, Feiyan
;
Ma, Zhongyi
;
Luo, Xing
;
Wang, Yahua
;
Liu, Xinlong
; et al.
Favorite
|
TC[WOS]:
1
TC[Scopus]:
1
IF:
4.5
/
4.6
|
Submit date:2024/07/04
Chemotherapy Resistance
Paclitaxel
Paclitaxel-ginsenoside Micelles
Prostate Cancer Treatment
Severe Neurotoxicity
Antibody Recognition of Human Epidermal Growth Factor Receptor-2 (HER2) Juxtamembrane Domain Enhances Anti-Tumor Response of Chimeric Antigen Receptor (CAR)-T Cells
Journal article
Zhou, Guangyu, Fu, Shengyu, Zhang, Yunsen, Li, Shuang, Guo, Ziang, Ouyang, Defang, Ying, Tianlei, Lu, Yinying, Zhao, Qi. Antibody Recognition of Human Epidermal Growth Factor Receptor-2 (HER2) Juxtamembrane Domain Enhances Anti-Tumor Response of Chimeric Antigen Receptor (CAR)-T Cells[J]. Antibodies, 2024, 13(2), 45.
Authors:
Zhou, Guangyu
;
Fu, Shengyu
;
Zhang, Yunsen
;
Li, Shuang
;
Guo, Ziang
; et al.
Favorite
|
TC[WOS]:
0
TC[Scopus]:
0
IF:
3.0
/
4.7
|
Submit date:2024/08/05
Car-t Cell
Her2
Monoclonal Antibody
Trastuzumab
A Comprehensive Analysis of Biopharmaceutical Products Listed in the FDA’s Purple Book
Journal article
Chen, Fuduan, Zhong, Hao, Chan, Ging, Ouyang, Defang. A Comprehensive Analysis of Biopharmaceutical Products Listed in the FDA’s Purple Book[J]. AAPS PharmSciTech, 2024, 25(5), 88.
Authors:
Chen, Fuduan
;
Zhong, Hao
;
Chan, Ging
;
Ouyang, Defang
Favorite
|
TC[WOS]:
0
TC[Scopus]:
0
IF:
3.4
/
3.5
|
Submit date:2024/05/16
Biologics
Biopharmaceutical Landscape
Dosage Form
Excipient
Purple Book
Perylenedioic Acid-Derived Carbon Dots with Near 100% Quantum Yield in Aqueous Solution for Lasing and Lighting
Journal article
Liu, Yupeng, Wang, Bingzhe, Zhang, Yunsen, Guo, Jia, Wu, Xiaoyi, Ouyang, Defang, Chen, Shi, Chen, Yeqing, Wang, Shuangpeng, Xing, Guichuan, Tang, Zikang, Qu, Songnan. Perylenedioic Acid-Derived Carbon Dots with Near 100% Quantum Yield in Aqueous Solution for Lasing and Lighting[J]. Advanced Functional Materials, 2024.
Authors:
Liu, Yupeng
;
Wang, Bingzhe
;
Zhang, Yunsen
;
Guo, Jia
;
Wu, Xiaoyi
; et al.
Favorite
|
TC[WOS]:
15
TC[Scopus]:
11
IF:
18.5
/
19.6
|
Submit date:2024/05/16
Aqueous-based Laser
Carbon Dots
Cross-condensation
Near-unity Plqy
White Leds
Recent advances in the metal/organic hybrid nanomaterials for cancer theranostics
Review article
2024
Authors:
Ye, Zhaoyi
;
Bao, Ying
;
Chen, Zefeng
;
Ye, Huiling
;
Feng, Zhenzhen
; et al.
Favorite
|
TC[WOS]:
7
TC[Scopus]:
8
IF:
20.3
/
19.9
|
Submit date:2024/05/02
Cancer Theranostics
Metal/organic Hybrid Nanomaterials
Organic Ligand
Organic crystal structure prediction via coupled generative adversarial networks and graph convolutional networks
Journal article
Ye, Zhuyifan, Wang, Nannan, Zhou, Jiantao, Ouyang, Defang. Organic crystal structure prediction via coupled generative adversarial networks and graph convolutional networks[J]. Innovation, 2024, 5(2), 100562.
Authors:
Ye, Zhuyifan
;
Wang, Nannan
;
Zhou, Jiantao
;
Ouyang, Defang
Favorite
|
TC[WOS]:
5
TC[Scopus]:
5
IF:
33.2
/
31.8
|
Submit date:2024/04/02
Monte-carlo
Energy
Polymorph