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Immunogenic cell death inducers for cancer therapy: An emerging focus on natural products Journal article
Zhang, Le Le, Zhang, Du Juan, Shi, Jia Xin, Huang, Mu Yang, Yu, Jia Mei, Chen, Xu Jia, Wei, Xiao, Zou, Liang, Lu, Jin Jian. Immunogenic cell death inducers for cancer therapy: An emerging focus on natural products[J]. Phytomedicine, 2024, 132, 155828.
Authors:  Zhang, Le Le;  Zhang, Du Juan;  Shi, Jia Xin;  Huang, Mu Yang;  Yu, Jia Mei; et al.
Favorite | TC[Scopus]:1  IF:6.7/6.2 | Submit date：2024/07/04
Cancer Therapy  Immunogenic Cell Death  Natural Products  Regulated Cell Death  Tumor Immune Microenvironment  
Mechanisms of Cynarine for treatment of non-alcoholic fatty liver disease based on the integration of network pharmacology, molecular docking and cell experiment Journal article
Chun‑Yong Sun, Le‑Le Yang, Pan Zhao, Pei‑Zheng Yan, Jia Li, Dong‑Sheng Zhao. Mechanisms of Cynarine for treatment of non-alcoholic fatty liver disease based on the integration of network pharmacology, molecular docking and cell experiment[J]. HEREDITAS, 2022, 159(1), 44.
Authors:  Chun‑Yong Sun;  Le‑Le Yang;  Pan Zhao;  Pei‑Zheng Yan;  Jia Li; et al.
Favorite | TC[WOS]:5 TC[Scopus]:6  IF:2.1/2.6 | Submit date：2023/01/30
Cynarine  Non‑alcoholic Fatty Liver Disease  Network Pharmacology  Integration Analysis  Molecular Docking  
Glutathione peroxidase 8 expression on cancer cells and cancer-associated fibroblasts facilitates lung cancer metastasis Journal article
Xu, Yu Lian, Yuan, Luo Wei, Jiang, Xiao Ming, Su, Min Xia, Huang, Mu Yang, Chen, Yu Chi, Zhang, Le Le, Chen, Xiuping, Zhu, Hong, Lu, Jin Jian. Glutathione peroxidase 8 expression on cancer cells and cancer-associated fibroblasts facilitates lung cancer metastasis[J]. MedComm, 2022, 3(3), e152.
Authors:  Xu, Yu Lian;  Yuan, Luo Wei;  Jiang, Xiao Ming;  Su, Min Xia;  Huang, Mu Yang; et al.
Favorite | TC[WOS]:5 TC[Scopus]:6 | Submit date：2022/10/06
Caf  Focal Adhesion  Gpx8  Lung Cancer  Metastasis  
Buxue Yimu Pills improve angiogenesis and blood flow in experimental zebrafish and rat models Journal article
Le Le Zhang, Feiya Sheng, Yan He, Yong Yang, Ying Fan Hu, Wei Li, Peng Li, Meng Yao Wu, Yun Gong, Yamei Zhang, Liang Zou. Buxue Yimu Pills improve angiogenesis and blood flow in experimental zebrafish and rat models[J]. Journal of Ethnopharmacology, 2022, 289, 115002.
Authors:  Le Le Zhang;  Feiya Sheng;  Yan He;  Yong Yang;  Ying Fan Hu; et al.
Favorite | TC[WOS]:5 TC[Scopus]:6  IF:4.8/4.8 | Submit date：2022/05/13
Buxue Yimu Pills  Angiogenesis  Blood Flow  Zebrafish  Medical Abortion Rats  
c-MYC-mediated TRIB3/P62+ aggresomes accumulation triggers paraptosis upon the combination of everolimus and ginsenoside Rh2 Journal article
Su, Min Xia, Xu, Yu Lian, Jiang, Xiao Ming, Huang, Mu Yang, Zhang, Le Le, Yuan, Luo Wei, Xu, Xiao Huang, Zhu, Qi, Gao, Jian Li, Lu, Jia Hong, Chen, Xiuping, Huang, Ming Qing, Wang, Yitao, Lu, Jin Jian. c-MYC-mediated TRIB3/P62+ aggresomes accumulation triggers paraptosis upon the combination of everolimus and ginsenoside Rh2[J]. Acta Pharmaceutica Sinica B, 2022, 12(3), 1240-1253.
Authors:  Su, Min Xia;  Xu, Yu Lian;  Jiang, Xiao Ming;  Huang, Mu Yang;  Zhang, Le Le; et al.
Favorite | TC[WOS]:10 TC[Scopus]:11  IF:14.7/14.1 | Submit date：2022/04/06
Aggresomes  C-myc  Everolimus  Ginsenoside Rh2  Lung Cancer  P62  Paraptosis  Trib3  
Myricetin inhibits interferon-γ-induced PD-L1 and IDO1 expression in lung cancer cells Journal article
Chen, Yu Chi, He, Xin Ling, Qi, Lu, Shi, Wei, Yuan, Luo Wei, Huang, Mu Yang, Xu, Yu Lian, Chen, Xiuping, Gu, Lei, Zhang, Le Le, Lu, Jin Jian. Myricetin inhibits interferon-γ-induced PD-L1 and IDO1 expression in lung cancer cells[J]. Biochemical Pharmacology, 2022, 197, 114940.
Authors:  Chen, Yu Chi;  He, Xin Ling;  Qi, Lu;  Shi, Wei;  Yuan, Luo Wei; et al.
Favorite | TC[WOS]:21 TC[Scopus]:22  IF:5.3/5.2 | Submit date：2022/03/28
Indoleamine 2, 3-dioxygenase 1  Interferon-γ  Lung Cancer  Myricetin  Programmed Death Ligand-1  
Bioactive platycodins from Platycodonis Radix: Phytochemistry, pharmacological activities, toxicology and pharmacokinetics Journal article
Zhang,Le Le, Huang,Mu Yang, Yang,Yong, Huang,Ming Qing, Shi,Jia Jie, Zou,Liang, Lu,Jin Jian. Bioactive platycodins from Platycodonis Radix: Phytochemistry, pharmacological activities, toxicology and pharmacokinetics[J]. Food Chemistry, 2020, 327, 127029.
Authors:  Zhang,Le Le;  Huang,Mu Yang;  Yang,Yong;  Huang,Ming Qing;  Shi,Jia Jie; et al.
Favorite | TC[WOS]:64 TC[Scopus]:68  IF:8.5/8.2 | Submit date：2021/03/02
Pharmacokinetics  Pharmacological Activities  Phytochemistry  Platycodins  Platycodonis Radix  Toxicology  
TGFβ2-mediated epithelial–mesenchymal transition and NF-κB pathway activation contribute to osimertinib resistance Journal article
Jiang,Xiao ming, Xu,Yu lian, Yuan,Luo wei, Zhang,Le le, Huang,Mu yang, Ye,Zi han, Su,Min xia, Chen,Xiu ping, Zhu,Hong, Ye,Richard D., Lu,Jin jian. TGFβ2-mediated epithelial–mesenchymal transition and NF-κB pathway activation contribute to osimertinib resistance[J]. Acta Pharmacologica Sinica, 2020, 42(3), 451-459.
Authors:  Jiang,Xiao ming;  Xu,Yu lian;  Yuan,Luo wei;  Zhang,Le le;  Huang,Mu yang; et al.
Favorite | TC[WOS]:40 TC[Scopus]:39  IF:6.9/7.6 | Submit date：2021/03/01
Egfr Mutant Non-small Cell Lung Cancer  Emt  Nf-κb  Osimertinib Resistance  Tgfβ2  
Nagilactone E increases PD-L1 expression through activation of c-Jun in lung cancer cells Journal article
CHEN,Yu Chi, HUANG,Mu Yang, ZHANG,Le Le, FENG,Zhe Ling, JIANG,Xiao Ming, YUAN,Luo Wei, HUANG,Run Yue, LIU,Bo, YU,Hua, WANG,Yi Tao, CHEN,Xiu Ping, LIN,Li Gen, LU,Jin Jian. Nagilactone E increases PD-L1 expression through activation of c-Jun in lung cancer cells[J]. Chinese Journal of Natural Medicines, 2020, 18(7), 517-525.
Authors:  CHEN,Yu Chi;  HUANG,Mu Yang;  ZHANG,Le Le;  FENG,Zhe Ling;  JIANG,Xiao Ming; et al.
Favorite | TC[WOS]:15 TC[Scopus]:15  IF:4.0/3.7 | Submit date：2021/03/01
Programmed Death Ligand 1  Nagilactone e  Lung Cancer  C-jun  Jnk  
Nagilactone E suppresses TGF-beta 1-induced epithelial-mesenchymal transition, migration and invasion in non-small cell lung cancer cells Journal article
Le-Le Zhang, Xiao-Ming Jiang, Mu-Yang Huang, Zhe-Ling Feng, Xiuping Chen, Yitao Wang, Hua Li, Ao Li, Li-Gen Lin, Jin-Jian Lu. Nagilactone E suppresses TGF-beta 1-induced epithelial-mesenchymal transition, migration and invasion in non-small cell lung cancer cells[J]. PHYTOMEDICINE, 2019, 52, 32-39.
Authors:  Le-Le Zhang;  Xiao-Ming Jiang;  Mu-Yang Huang;  Zhe-Ling Feng;  Xiuping Chen; et al.
Favorite | TC[WOS]:19 TC[Scopus]:18  IF:6.7/6.2 | Submit date：2020/01/09
Nagilactone e  Tgf-β1  Emt  Smad