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Drug screening on digital microfluidics for cancer precision medicine Journal article
Zhai, Jiao, Liu, Yingying, Ji, Weiqing, Huang, Xinru, Wang, Ping, Li, Yunyi, Li, Haoran, Wong, Ada Hang Heng, Zhou, Xiong, Chen, Ping, Wang, Lianhong, Yang, Ning, Chen, Chi, Chen, Haitian, Mak, Pui In, Deng, Chu Xia, Martins, Rui, Yang, Mengsu, Ho, Tsung Yi, Yi, Shuhong, Yao, Hailong, Jia, Yanwei. Drug screening on digital microfluidics for cancer precision medicine[J]. Nature Communications, 2024, 15(1), 4363.
Authors:  Zhai, Jiao;  Liu, Yingying;  Ji, Weiqing;  Huang, Xinru;  Wang, Ping; et al.
Favorite | TC[WOS]:4 TC[Scopus]:5  IF:14.7/16.1 | Submit date：2024/06/05
In-vitro  On-chip  Cell  Epirubicin  Breast  Angiogenesis  Glycolysis  Inhibitors  Platform  Feedback  
Bubble-Inspired Multifunctional Magnetic Microrobots for Integrated Multidimensional Targeted Biosensing Journal article
Xu, Zichen, Sun, Heng, Chen, Yuanhe, Yu, Hon Ho, Deng, Chu Xia, Xu, Qingsong. Bubble-Inspired Multifunctional Magnetic Microrobots for Integrated Multidimensional Targeted Biosensing[J]. Nano Letters, 2024, 24(44), 13945−13954.
Authors:  Xu, Zichen;  Sun, Heng;  Chen, Yuanhe;  Yu, Hon Ho;  Deng, Chu Xia; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:9.6/10.1 | Submit date：2024/11/05
Bubble Microrobot  Magnetic Actuation  Biosensing  Medical Imaging  Targeted Delivery  Magnetic Particles  
AI-powered interpretable imaging phenotypes noninvasively characterize tumor microenvironment associated with diverse molecular signatures and survival in breast cancer Journal article
Lv, Tianxu, Hong, Xiaoyan, Liu, Yuan, Miao, Kai, Sun, Heng, Li, Lihua, Deng, Chuxia, Jiang, Chunjuan, Pan, Xiang. AI-powered interpretable imaging phenotypes noninvasively characterize tumor microenvironment associated with diverse molecular signatures and survival in breast cancer[J]. Computer Methods and Programs in Biomedicine, 2024, 243, 107857.
Authors:  Lv, Tianxu;  Hong, Xiaoyan;  Liu, Yuan;  Miao, Kai;  Sun, Heng; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:4.9/5.5 | Submit date：2024/02/22
Breast Cancer  Deep Learning  Interpretable Imaging Phenotypes  Intra-tumor Heterogeneity  Tumor Microenvironment  
Comprehensive analysis of tumor microenvironment reveals prognostic ceRNA network related to immune infiltration in sarcoma Journal article
Leng Dongliang, Yang Ziy, Sun Heng, Song Chengcheng, Huang Chen, Ip Ka-U, Chen Guokai, Deng Chu-Xia, Zhang Xiaohua Douglas, Zhao Qi. Comprehensive analysis of tumor microenvironment reveals prognostic ceRNA network related to immune infiltration in sarcoma[J]. Clinical Cancer Research, 2023, 29(19), 3986-4001.
Authors:  Leng Dongliang;  Yang Ziy;  Sun Heng;  Song Chengcheng;  Huang Chen; et al.
Adobe PDF | Favorite | TC[WOS]:3 TC[Scopus]:3  IF:10.0/11.1 | Submit date：2023/08/25
BRCA1 Insufficiency Induces a Hypersialylated Acidic Tumor Microenvironment That Promotes Metastasis and Immunotherapy Resistance Journal article
Xiaodong Shu, Jianjie Li, Un In Chan, Sek Man Su, Changxiang Shi, Xin Zhang, Tingting An, Jun Xu, Lihua Mo, Jianlin Liu, Yuqing Wang, Xiaoling Li, Min Deng, Josh Haipeng Lei, Chunfei Wang, Hao Tian, Sun Heng, Joong Sup Shim, Xuanjun Zhang, Yunlu Dai, Zhicheng Yao, Xiaying Kuang, Ying Lin, Chu-Xia Deng, Xiaoling Xu. BRCA1 Insufficiency Induces a Hypersialylated Acidic Tumor Microenvironment That Promotes Metastasis and Immunotherapy Resistance[J]. CANCER RESEARCH, 2023, 83(15), 2614-2633.
Authors:  Xiaodong Shu;  Jianjie Li;  Un In Chan;  Sek Man Su;  Changxiang Shi; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:12.5/11.6 | Submit date：2023/08/30
Machine learning model for anti-cancer drug combinations: Analysis, prediction, and validation Journal article
Zhou,Jing Bo, Tang,Dongyang, He,Lin, Lin,Shiqi, Lei,Josh Haipeng, Sun,Heng, Xu,Xiaoling, Deng,Chu Xia. Machine learning model for anti-cancer drug combinations: Analysis, prediction, and validation[J]. Pharmacological Research, 2023, 194, 106830.
Authors:  Zhou,Jing Bo;  Tang,Dongyang;  He,Lin;  Lin,Shiqi;  Lei,Josh Haipeng; et al.
Favorite | TC[WOS]:6 TC[Scopus]:6  IF:9.1/9.0 | Submit date：2023/08/03
Bortezomib (Pubchem Cid: 387447)  Cepharanthine (Pubchem Cid: 10206)  Docetaxel (Taxotere) (Pubchem Cid: 11970251)  Drug Combination Therapy  Flunarizine Dihydrochloride (Pubchem Cid: 5282407)  Lapatinib Ditosylate (Pubchem Cid: 9941095)  Machine Learning  Pazopanib Hydrochloride (Pubchem Cid: 11525740)  Potential Combination Biomarkers  Tamoxifen Citrate (Pubchem Cid: 2733525)  Three-dimensional Tumor Slice Culture  Vatalanib (Pubchem Cid: 151194)  Vincristine (Pubchem Cid: 5978)  Xl-184 (Cabozantinib) (Pubchem Cid: 25102847)  
Cullin-5 deficiency orchestrates the tumor microenvironment to promote mammary tumor development through CREB1-CCL2 signaling Journal article
Chen, Si, Shao, Fangyuan, Zeng, Jianming, Guo, Sen, Wang, Lijian, Sun, Heng, Lei, Josh Haipeng, Lyu, Xueying, Gao, Shuai, Chen, Qiang, Miao, Kai, Xu, Xiaoling, Deng, Chu Xia. Cullin-5 deficiency orchestrates the tumor microenvironment to promote mammary tumor development through CREB1-CCL2 signaling[J]. Science advances, 2023, 9(3).
Authors:  Chen, Si;  Shao, Fangyuan;  Zeng, Jianming;  Guo, Sen;  Wang, Lijian; et al.
Favorite | TC[WOS]:6 TC[Scopus]:7  IF:11.7/13.7 | Submit date：2023/02/08
S100A9-CXCL12 activation in BRCA1-mutant breast cancer promotes an immunosuppressive microenvironment associated with resistance to immunotherapy Journal article
Jianjie Li, Xiaodong Shu, Jun Xu, Sek Man Su, Un In Chan, Lihua Mo, Jianlin Liu, Xin Zhang, Ragini Adhav, Qiang Chen, Yuqing Wang, Tingting An, Xu Zhang, Xueying Lyu, Xiaoling Li, Josh Haipeng Lei, Kai Miao, Heng Sun, Fuqiang Xing, Aiping Zhang, Chuxia Deng, Xiaoling Xu. S100A9-CXCL12 activation in BRCA1-mutant breast cancer promotes an immunosuppressive microenvironment associated with resistance to immunotherapy[J]. Nature Communications, 2022, 13(1), 1481.
Authors:  Jianjie Li;  Xiaodong Shu;  Jun Xu;  Sek Man Su;  Un In Chan; et al.
Favorite | TC[WOS]:37 TC[Scopus]:42  IF:14.7/16.1 | Submit date：2022/05/13
Conformalized temporal convolutional quantile regression networks for wind power interval forecasting Journal article
Hu, Jianming, Luo, Qingxi, Tang, Jingwei, Heng, Jiani, Deng, Yuwen. Conformalized temporal convolutional quantile regression networks for wind power interval forecasting[J]. ENERGY, 2022, 248, 123497.
Authors:  Hu, Jianming;  Luo, Qingxi;  Tang, Jingwei;  Heng, Jiani;  Deng, Yuwen
Favorite | TC[WOS]:27 TC[Scopus]:33  IF:9.0/8.2 | Submit date：2022/05/13
Conformalized Quantile Regression  Temporal Convolutional Network  Wind Power Interval Prediction  
Tumor heterogeneity reshapes the tumor microenvironment to influence drug resistance Review article
2022
Authors:  Zhang, Aiping;  Miao, Kai;  Sun, Heng;  Deng, Chu Xia
Favorite | TC[WOS]:88 TC[Scopus]:96  IF:8.2/8.3 | Submit date：2022/07/29
Drug Resistance  Tumor Heterogeneity  Tumor Microenvironment