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Editorial: Therapeutic antibody domains against cancer Other
2023-08-28
Authors:  Zhao, Qi;  Li, Wei;  Dimitrov, Dimiter S.
Favorite | TC[WOS]:0 TC[Scopus]:0 | Submit date：2023/08/30
Antibody Domain  Bispecific Antibody  Cancer  Immune Checkpoint  Monoclonal Antibody  Phage Display  
An insulin growth factor-I/II-neutralizing monoclonal antibody in combination with epidermal growth factor receptor inhibitors potently inhibits tumor cell growth Journal article
Ma, Guofang, Tan, Chengyue, Shan, Yaming, Shao, Ningyi, Wang, Feng, Dimitrov, Dimiter S., Wang, Liping, Zhao, Qi. An insulin growth factor-I/II-neutralizing monoclonal antibody in combination with epidermal growth factor receptor inhibitors potently inhibits tumor cell growth[J]. Journal of Cancer, 2022, 13(5), 1830-1836.
Authors:  Ma, Guofang;  Tan, Chengyue;  Shan, Yaming;  Shao, Ningyi;  Wang, Feng; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:3.3/3.3 | Submit date：2022/05/17
Egfr  Gefitinib  Igf-i  Igf-ii  M708.5  Monoclonal Antibody  
Recombinant-fully-human-antibody decorated highly-stable far-red AIEdots for in vivo HER-2 receptor-targeted imaging Journal article
Wu, Yayun, Chen, Zhizhen, Zhang, Pengfei, Zhou, Lihua, Jiang, Tao, Chen, Huajie, Gong, Ping, Dimitrov, Dimiter S., Cai, Lintao, Zhao, Qi. Recombinant-fully-human-antibody decorated highly-stable far-red AIEdots for in vivo HER-2 receptor-targeted imaging[J]. CHEMICAL COMMUNICATIONS, 2018, 54(53), 7314-7317.
Authors:  Wu, Yayun;  Chen, Zhizhen;  Zhang, Pengfei;  Zhou, Lihua;  Jiang, Tao; et al.
Favorite | TC[WOS]:15 TC[Scopus]:15  IF:4.3/4.4 | Submit date：2018/10/30
A dual-specific IGF-I/II human engineered antibody domain inhibits IGF signaling in breast cancer cells Journal article
Zhizhen Chen, Jie Liu, Dafeng Chu, Yaming Shan, Guixing Ma, Hongmin Zhang, Xiaohua Douglas Zhang, Pu Wang, Qiang Chen, Chuxia Deng, Weizao Chen, Dimiter Dimitrov, Qi Zhao. A dual-specific IGF-I/II human engineered antibody domain inhibits IGF signaling in breast cancer cells[J]. International Journal of Biological Sciences, 2018, 14(7), 799–806.
Authors:  Zhizhen Chen;  Jie Liu;  Dafeng Chu;  Yaming Shan;  Guixing Ma; et al.
Favorite | TC[WOS]:9 TC[Scopus]:9  IF:8.2/8.3 | Submit date：2018/12/17
Insulin-like Growth Factor  Yeast Display  Affinity Maturation  Ead  
N-terminal alpha-amino group modification of antibodies using a site-selective click chemistry method Journal article
De-zhi Li, Bing-nan Han, Rui Wei, Gui-yang Yao, Zhizhen Chen, Jie Liu, Terence C.W. Poon, Wu Su, Zhongyu Zhu, Dimiter S. Dimitrov, Qi Zhao. N-terminal alpha-amino group modification of antibodies using a site-selective click chemistry method[J]. MABS, 2018, 10(5), 712-719.
Authors:  De-zhi Li;  Bing-nan Han;  Rui Wei;  Gui-yang Yao;  Zhizhen Chen; et al.
Favorite | TC[WOS]:25 TC[Scopus]:26  IF:5.6/5.8 | Submit date：2020/06/30
Antibody  Antibody Engineering  Antibody-drug Conjugate  Click Chemistry  Site-specific Modification  
Engineered antibody CH2 domains binding to nucleolin: Isolation, characterization and improvement of aggregation Journal article
Li, Dezhi, Gong, Rui, Zheng, Jun, Chen, Xihai, Dimitrov, Dimiter S., Zhao, Qi. Engineered antibody CH2 domains binding to nucleolin: Isolation, characterization and improvement of aggregation[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 485(2), 446-453.
Authors:  Li, Dezhi;  Gong, Rui;  Zheng, Jun;  Chen, Xihai;  Dimitrov, Dimiter S.; et al.
Favorite | TC[WOS]:20 TC[Scopus]:20  IF:2.5/2.7 | Submit date：2018/10/30
Antibody Domain  Ch2  Nucleolin  Yeast Display  Monoclonal Antibody  Aggregation Prone Region  
Human monoclonal antibodies that bind insulin-like growth factor (IGF) I and II Patent
专利类型: 发明专利 Invention, 专利号: US9150644B2, 申请日期: 2012-04-11, 公开日期: 2015-10-06
Authors:  Dimitrov, Dimiter S.;  Zhu, Zhongyu;  Zhao, Qi
Favorite |  | Submit date：2022/05/21
A dual specific anti-IGF-1/IGF-2 human monoclonal antibody alone and in combination with temsirolimus for therapy of neuroblastoma Journal article
Qi Zhao, Hoa Tran, Dimiter S. Dimitrov, Nai-Kong V. Cheung. A dual specific anti-IGF-1/IGF-2 human monoclonal antibody alone and in combination with temsirolimus for therapy of neuroblastoma[J]. INTERNATIONAL JOURNAL OF CANCER, 2015, 137(9), 2243-2252.
Authors:  Qi Zhao;  Hoa Tran;  Dimiter S. Dimitrov;  Nai-Kong V. Cheung
Favorite | TC[WOS]:21 TC[Scopus]:21  IF:5.7/6.0 | Submit date：2019/01/23
Igf-1  Igf-2  Temsirolimus  Chemotherapy  Neuroblastoma  
Human monoclonal antibodies targeting nonoverlapping epitopes on insulin-like growth factor II as a novel type of candidate cancer therapeutics Journal article
Weizao Chen, Yang Feng, Qi Zhao, Zhongyu Zhu, Dimiter S. Dimitrov. Human monoclonal antibodies targeting nonoverlapping epitopes on insulin-like growth factor II as a novel type of candidate cancer therapeutics[J]. MOLECULAR CANCER THERAPEUTICS, 2012, 11(7), 1400-1410.
Authors:  Weizao Chen;  Yang Feng;  Qi Zhao;  Zhongyu Zhu;  Dimiter S. Dimitrov
Favorite | TC[WOS]:24 TC[Scopus]:27  IF:5.3/5.4 | Submit date：2019/01/23
Human monoclonal antibodies to IGF1/2 with picomolar affinity Journal article
Qi Zhao, Yang Feng, Zhongyu Zhu, Dimiter S. Dimitrov. Human monoclonal antibodies to IGF1/2 with picomolar affinity[J]. MOLECULAR CANCER THERAPEUTICS, 2011, 10(9), 1677-1685.
Authors:  Qi Zhao;  Yang Feng;  Zhongyu Zhu;  Dimiter S. Dimitrov
Favorite | TC[WOS]:35 TC[Scopus]:36  IF:5.3/5.4 | Submit date：2019/01/23
Mab  Igf2  Picomolar Affinity  Phage Display  Yeast Display  Igf1