In this paper, based on the previous research experiences in the lumped parameter modeling and study of active control mounts (ACM) model, an analytical model of active ACM in powertrain is developed and implemented in MATLAB. In order to validate this newly developed model in this work, a finite element analysis (FEA) method is conducted in ANSYS and the results of FEA is compared with analytical model for validation. After the validation, the control strategy is integrated into the analytical model by using the linear quadratic regulator (LQR) method. Numerical results show a good control performance. Furthermore, this work examines the application of genetic algorithms (GA) in optimizing the weight matrices of LQR. An optimal configuration is obtained and thus this approach could help the practical design of ACM systems.