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Enhancing trabecular CT scans based on deep learning with multi-strategy fusion
Ge, Peixuan1,4; Li, Shibo2; Liang, Yefeng1; Zhang, Shuwei3; Zhang, Lihai3; Hu, Ying1; Yao, Liang1,4; Wong, Pak Kin4
2024-09
Source PublicationComputerized Medical Imaging and Graphics
ISSN0895-6111
Volume116Pages:102410
Abstract

Trabecular bone analysis plays a crucial role in understanding bone health and disease, with applications like osteoporosis diagnosis. This paper presents a comprehensive study on 3D trabecular computed tomography (CT) image restoration, addressing significant challenges in this domain. The research introduces a backbone model, Cascade-SwinUNETR, for single-view 3D CT image restoration. This model leverages deep layer aggregation with supervision and capabilities of Swin-Transformer to excel in feature extraction. Additionally, this study also brings DVSR3D, a dual-view restoration model, achieving good performance through deep feature fusion with attention mechanisms and Autoencoders. Furthermore, an Unsupervised Domain Adaptation (UDA) method is introduced, allowing models to adapt to input data distributions without additional labels, holding significant potential for real-world medical applications, and eliminating the need for invasive data collection procedures. The study also includes the curation of a new dual-view dataset for CT image restoration, addressing the scarcity of real human bone data in Micro-CT. Finally, the dual-view approach is validated through downstream medical bone microstructure measurements. Our contributions open several paths for trabecular bone analysis, promising improved clinical outcomes in bone health assessment and diagnosis.

KeywordTrabecular Ct Analysis Medical Image Restoration Dual-view Learning Unsupervised Domain Adaptation Deep Supervision Medical Image Segmentation Medical Image Processing
DOI10.1016/j.compmedimag.2024.102410
URLView the original
Indexed BySCIE
Language英語English
WOS Research AreaEngineering ; Radiology ; Nuclear Medicine & Medical Imaging
WOS SubjectEngineering, Biomedical ; Radiology, Nuclear Medicine & Medical Imaging
WOS IDWOS:001346609200001
PublisherPERGAMON-ELSEVIER SCIENCE LTDTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
Scopus ID2-s2.0-85196383546
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Document TypeJournal article
CollectionDEPARTMENT OF ELECTROMECHANICAL ENGINEERING
Corresponding AuthorHu, Ying; Wong, Pak Kin
Affiliation1.Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, Guangdong, China
2.School of Automotive and Transportation Engineering, Shenzhen Polytechnic University, Shenzhen, 518055, Guangdong, China
3.Department of Orthopaedics, Chinese PLA General Hospital, Beijing, China
4.Department of Electromechanical Engineering, University of Macau, Taipa, 999078, Macau, China
First Author AffilicationUniversity of Macau
Corresponding Author AffilicationUniversity of Macau
Recommended Citation
GB/T 7714
Ge, Peixuan,Li, Shibo,Liang, Yefeng,et al. Enhancing trabecular CT scans based on deep learning with multi-strategy fusion[J]. Computerized Medical Imaging and Graphics, 2024, 116, 102410.
APA Ge, Peixuan., Li, Shibo., Liang, Yefeng., Zhang, Shuwei., Zhang, Lihai., Hu, Ying., Yao, Liang., & Wong, Pak Kin (2024). Enhancing trabecular CT scans based on deep learning with multi-strategy fusion. Computerized Medical Imaging and Graphics, 116, 102410.
MLA Ge, Peixuan,et al."Enhancing trabecular CT scans based on deep learning with multi-strategy fusion".Computerized Medical Imaging and Graphics 116(2024):102410.
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