Residential College | false |
Status | 已發表Published |
Versatile magnetic hydrogel soft capsule microrobots for targeted delivery | |
Xu, Zichen1; Wu, Zehao1; Yuan, Mingzhe2; Chen, Yuanhe1; Ge, Wei2; Xu, Qingsong1 | |
2023-04-25 | |
Source Publication | iScience |
ISSN | 2589-0042 |
Volume | 26Issue:5Pages:106727 |
Other Abstract | Maintaining the completeness of cargo and achieving on-demand cargo release during long navigations in complex environments of the internal human body is crucial. Herein, we report a novel design of magnetic hydrogel soft capsule microrobots, which can be physically disintegrated to release microrobot swarms and diverse cargoes with almost no loss. CaCl2 solution and magnetic powders are utilized to produce suspension droplets, which are put into sodium alginate solution to generate magnetic hydrogel membranes for enclosing microrobot swarms and cargos. Low-density rotating magnetic fields drive the microrobots. Strong gradient magnetic fields break the mechanical structure of the hydrogel shell to implement on-demand release. Under the guidance of ultrasound imaging, the microrobot is remotely controlled in acidic or alkaline environments, similar to those in the human digestion system. The proposed capsule microrobots provide a promising solution for targeted cargo delivery in the internal human body. |
Keyword | Biomedical Materials Magnetic Property Robotics |
DOI | 10.1016/j.isci.2023.106727 |
URL | View the original |
Indexed By | SCIE |
Language | 英語English |
WOS Research Area | Science & Technology - Other Topics |
WOS Subject | Multidisciplinary Sciences |
WOS ID | WOS:001000985500001 |
Publisher | CELL PRESS, 50 HAMPSHIRE ST, FLOOR 5, CAMBRIDGE, MA 02139 |
Scopus ID | 2-s2.0-85156270699 |
Fulltext Access | |
Citation statistics | |
Document Type | Journal article |
Collection | Centre of Reproduction, Development and Aging Faculty of Health Sciences DEPARTMENT OF ELECTROMECHANICAL ENGINEERING DEPARTMENT OF BIOMEDICAL SCIENCES |
Corresponding Author | Ge, Wei; Xu, Qingsong |
Affiliation | 1.Department of Electromechanical Engineering, Faculty of Science and Technology, University of Macau, Macau, China 2.Department of Biomedical Sciences and Centre of Reproduction, Development and Aging (CRDA), Faculty of Health Sciences, University of Macau, Macau, China |
First Author Affilication | Faculty of Science and Technology |
Corresponding Author Affilication | Centre of Reproduction, Development and Aging; Faculty of Science and Technology |
Recommended Citation GB/T 7714 | Xu, Zichen,Wu, Zehao,Yuan, Mingzhe,et al. Versatile magnetic hydrogel soft capsule microrobots for targeted delivery[J]. iScience, 2023, 26(5), 106727. |
APA | Xu, Zichen., Wu, Zehao., Yuan, Mingzhe., Chen, Yuanhe., Ge, Wei., & Xu, Qingsong (2023). Versatile magnetic hydrogel soft capsule microrobots for targeted delivery. iScience, 26(5), 106727. |
MLA | Xu, Zichen,et al."Versatile magnetic hydrogel soft capsule microrobots for targeted delivery".iScience 26.5(2023):106727. |
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