Background: The impact of internet or video game addiction on physical health and diagnosis as a kind of disorder has become a crucial public health issue among emerging adults. In 2018, World Health Organization classified gaming disorder as an international disease. However, relatively few studies have examined the relationship between game disorder and health-related physical fitness outcomes. Purpose: This study aimed to investigate the status and explore the relationship between the internet game disorder (IGD) and physical fitness (PF) of emerging adults in Macao. Methods: A cross-sectional study recruited 410 emerging adults (age range 18 – 22, 46.8% male and 53.2% female) in Macao. The physical fitness test has conducted to collect data, and the questionnaire included background information and Internet Gaming Disorder Scale (IGDS-20) with high internal reliability (α= .88), consisting of six components. In addition, One way ANOVA, t-test, and Pearson‘s correlation coefficient were used for data analysis. Result: The key findings included (1) Multivariate analysis indicated a significant effect of age, gender, year of study on the level of IGD and PF. (2) Muscle strength had a positive relationship with the IGD (r=.113, p<.05), while cardiovascular fitness and flexibility had a negative relationship with the IGD (r=-.126, p<.05；r=-.161, p <.01). Conclusions: The result is consistent with other related studies, and internet/video addiction affects different dimensions of physical issues. The level of IGD and PF among Macao emerging adults are correlated. Future studies may focus on the impact of cardiovascular fitness and flexibility on IGD.