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Multi-scale Multi-instance Multi-feature Joint Learning Broad Network (M3JLBN) for gastric intestinal metaplasia subtype classification
Lai, Qi1; Vong, Chi Man1; Wong, Pak Kin2; Wang, Shi Tong3; Yan, Tao2; Choi, I. Cheong4; Yu, Hon Ho4
2022-08-05
Source PublicationKnowledge-Based Systems
ISSN0950-7051
Volume249Pages:108960
Abstract

According to worldwide statistics, gastric intestinal metaplasia (GIM) is one of the most important characteristics for detecting the lesions in early gastric cancer. Currently, there are many detection methods employing multi-instance learning (MIL) on clinical medical images. For gastrointestinal endoscope (GE) images, there are very few existing works, which suffer from several issues: (i) only binary (i.e., healthy and GIM) cases are handled; (ii) the inter-instance correlation (i.e., the correlation between image patches or instances) cannot be captured; (iii) the multi-class label correlations among GIM subtype labels are neglected; (iv) multi-scale information is not considered. To address these issues, a novel Multi-scale Multi-instance Multi-feature Joint Learning Broad Network (MJBLN) is proposed for practically required GIM subtype classification, which includes two new modules: (i) A multi-class MIL prediction module is designed based on probabilistic representation which can provide multi-class label correlations (pseudo label) through labeled multi-scaling training samples; (ii) A novel multiple features joint learning broad network (MFJLBN) based on broad learning system (BLS) is designed by integrating a new representation layer and multi-scaling module, which can jointly obtain inter-instance correlation in feature space under multiple scales. Under these two modules, the proposed MJBLN jointly considers the multi-features of each instance at multiple scales to achieve more accurate subtype classification. The proposed MJBLN is evaluated on a limited available GIM dataset acquired from patients who visited the Endoscopy Center of Kiang Wu Hospital (Macau, China) between January 2017 and April 25, 2021. Our method can respectively improve the performance with at least 7.5%, 7.6%, 7.6% and 6.6% under the four-evaluation metrics (accuracy, precision, recall and F-score) compared to other classic methods.

KeywordGastric Intestinal Metaplasia Gastrointestinal Endoscope Images Joint Learning Broad Network Multi-instance Learning Multiple Features
DOI10.1016/j.knosys.2022.108960
URLView the original
Indexed BySCIE
Language英語English
WOS Research AreaComputer Science
WOS SubjectComputer Science, Artificial Intelligence
WOS IDWOS:000806839200001
PublisherELSEVIER,RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
Scopus ID2-s2.0-85133935515
Fulltext Access
Citation statistics
Document TypeJournal article
CollectionDEPARTMENT OF ELECTROMECHANICAL ENGINEERING
Corresponding AuthorVong, Chi Man
Affiliation1.Department of Computer and Information Science, University of Macau, Macao
2.Department of Electromechanical Engineering, University of Macau, Macao
3.School of AI and Computer Science, Jiangnan University, Wuxi, China
4.Kiang Wu Hospital, Macao
First Author AffilicationUniversity of Macau
Corresponding Author AffilicationUniversity of Macau
Recommended Citation
GB/T 7714
Lai, Qi,Vong, Chi Man,Wong, Pak Kin,et al. Multi-scale Multi-instance Multi-feature Joint Learning Broad Network (M3JLBN) for gastric intestinal metaplasia subtype classification[J]. Knowledge-Based Systems, 2022, 249, 108960.
APA Lai, Qi., Vong, Chi Man., Wong, Pak Kin., Wang, Shi Tong., Yan, Tao., Choi, I. Cheong., & Yu, Hon Ho (2022). Multi-scale Multi-instance Multi-feature Joint Learning Broad Network (M3JLBN) for gastric intestinal metaplasia subtype classification. Knowledge-Based Systems, 249, 108960.
MLA Lai, Qi,et al."Multi-scale Multi-instance Multi-feature Joint Learning Broad Network (M3JLBN) for gastric intestinal metaplasia subtype classification".Knowledge-Based Systems 249(2022):108960.
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