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AI-directed formulation strategy design initiates rational drug development Journal article
Wang, Nannan, Dong, Jie, Ouyang, Defang. AI-directed formulation strategy design initiates rational drug development[J]. Journal of Controlled Release, 2025, 378, 619-636.
Authors:  Wang, Nannan;  Dong, Jie;  Ouyang, Defang
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:10.5/10.6 | Submit date：2025/01/22
Formulation Strategy Design  Artificial Intelligence  Rational Drug Development  Poorly Water-soluble Drugs  Positive-unlabeled Learning  Partially Supervised Learning  
Quantitative analysis of excipients to the permeability of BCS class III drugs Journal article
Wang, Shuo, Liu, Dongyang, Ouyang, Defang. Quantitative analysis of excipients to the permeability of BCS class III drugs[J]. International Journal of Pharmaceutics, 2025, 668, 124958.
Authors:  Wang, Shuo;  Liu, Dongyang;  Ouyang, Defang
Favorite | TC[Scopus]:0  IF:5.3/5.6 | Submit date：2025/01/22
Bcs Iii Drugs  Sodium Lauryl Sulfate  Permeability  Quantitative Model  
Reflections and practices on key technical issues in the clinical translation of syndrome TCM new drugs 证候类中药新药临床转化关键技术问题的思考与实践 Review article
2024
Authors:  Tang, Jianyuan;  Ai, Yanling;  Liang, Dan;  Wan, Lina
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:1.1/0 | Submit date：2024/12/26
Clinical Evaluation  New Drug Development  New Traditional Chinese Medicine Drugs  Syndrome-based Traditional Chinese Medicine  Traditional Chinese Medicine Compound Formulations  
Recent advances in bioactivity-guided drug screening strategies for pre-clinical and clinical drug discovery Journal article
Chen, Simin, Shen, Chenxiao, Li, Wanyu, Fan, Yu, Yang, Dong Hua, Wang, Yitao, Feng, Ruibing, Li, Guodong, Zhong, Zhangfeng. Recent advances in bioactivity-guided drug screening strategies for pre-clinical and clinical drug discovery[J]. TrAC-Trends in Analytical Chemistry, 2024, 181, 118042.
Authors:  Chen, Simin;  Shen, Chenxiao;  Li, Wanyu;  Fan, Yu;  Yang, Dong Hua; et al.
Favorite | TC[WOS]:1 TC[Scopus]:0  IF:11.8/12.7 | Submit date：2024/12/05
Bioactivity-guided Drug Screening  Clinical Drugs  High-throughput Screening  Natural Products  
Editorial: Novel compounds from chemistry to druggable candidates Other
2024-09-01
Authors:  Rose, Pete;  Nasim, Jawad;  Zhu, Yi Zhun
Favorite | TC[WOS]:0 TC[Scopus]:0 | Submit date：2024/12/05
Bioactive  Drugs  Natural Products  Novel  Pharmacology  
Encoding and display technologies for combinatorial libraries in drug discovery: The coming of age from biology to therapy Review article
2024
Authors:  Fan, Yu;  Feng, Ruibing;  Zhang, Xinya;  Wang, Zhen Liang;  Xiong, Feng; et al.
Favorite | TC[WOS]:9 TC[Scopus]:8  IF:14.7/14.1 | Submit date：2024/05/16
Drug Screening  Dna-encoded Chemical Libraries  Phage Display  Peptide-encoded Chemical Libraries  Clinical Drugs  
Introducing enzymatic cleavage features and transfer learning realizes accurate peptide half-life prediction across species and organs Journal article
Tan, Xiaorong, Liu, Qianhui, Fang, Yanpeng, Yang, Sen, Chen, Fei, Wang, Jianmin, Ouyang, Defang, Dong, Jie, Zeng, Wenbin. Introducing enzymatic cleavage features and transfer learning realizes accurate peptide half-life prediction across species and organs[J]. Briefings in Bioinformatics, 2024, 25(4), bbae350.
Authors:  Tan, Xiaorong;  Liu, Qianhui;  Fang, Yanpeng;  Yang, Sen;  Chen, Fei; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:6.8/7.9 | Submit date：2024/08/05
Drug Design  Enzymatic Cleavage Features  Half-life  Machine Learning  Peptide Drugs  Transfer Learning  
Characteristics of clinical trials of new oncology drugs approved in China Journal article
Yang, Jing, Yang, Ji, Hu, Yuan Jia. Characteristics of clinical trials of new oncology drugs approved in China[J]. Cancer, 2024, 130(5), 671-682.
Authors:  Yang, Jing;  Yang, Ji;  Hu, Yuan Jia
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:6.1/6.7 | Submit date：2024/05/16
Clinical Evidence  Drug Lag  Novel Anticancer Drugs  Pivotal Clinical Trials  Programmed Death-1 (Pd-1) Inhibitors  Programmed Death-ligand 1 (Pd-l1) Inhibitors  
Editorial: Novel compounds from chemistry to druggable candidates Journal article
Rose, Pete, Nasim, Jawad, Zhu, Yi Zhun. Editorial: Novel compounds from chemistry to druggable candidates[J]. Frontiers in Chemistry, 2024, 12.
Authors:  Rose, Pete;  Nasim, Jawad;  Zhu, Yi Zhun
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:3.8/4.8 | Submit date：2024/12/26
bioactive  drugs  natural products  novel  pharmacology  
Ultrathin Cu-TCPP Nanosheet-Based Electrochemical Microsensor for Detecting the Immunosuppressive Drug Mycophenolic Acid Journal article
Deng, Mingshi, Jin, Wei, Yang, Wenjuan, Tian, Lingling, Gao, Xinghua, Wang, Xuefeng, Feng, Lingyan, Janyasupab, Metini, Zhou, Bingpu, Zhang, Yuan. Ultrathin Cu-TCPP Nanosheet-Based Electrochemical Microsensor for Detecting the Immunosuppressive Drug Mycophenolic Acid[J]. ACS Applied Nano Materials, 2023, 6(24), 22979-22988.
Authors:  Deng, Mingshi;  Jin, Wei;  Yang, Wenjuan;  Tian, Lingling;  Gao, Xinghua; et al.
Favorite | TC[WOS]:7 TC[Scopus]:6  IF:5.3/5.4 | Submit date：2024/02/22
Catalytic Activity  Cu−tcpp  Electrochemical Microsensor  Immunosuppressive Drugs  Ultrathin Mofs