UM

Browse/Search Results:  1-5 of 5 Help

Selected(0)Clear Items/Page:    Sort:
Novel Dichloroacetophenone-Based PDHK1 Inhibitors as Potent Anticancer Agents Journal article
Wu, Puhua, Zhang, Zhicheng, Zhou, Yan, Liu, Quan, Tam, Kin Yip, Su, Zhenhong. Novel Dichloroacetophenone-Based PDHK1 Inhibitors as Potent Anticancer Agents[J]. DRUG DESIGN DEVELOPMENT AND THERAPY, 2024, 18, 4661-4679.
Authors:  Wu, Puhua;  Zhang, Zhicheng;  Zhou, Yan;  Liu, Quan;  Tam, Kin Yip; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.7/4.8 | Submit date:2024/11/05
Pdhk1  Dichloroacetophenone  Allosteric Pocket  Anti-nsclc Activity  Tumor Xenograft Mouse Model  
Inhibition and structure-activity relationship of dietary flavones against three Loop 1-type human gut microbial β-glucuronidases Journal article
Wang, Panpan, Wu, Rongrong, Jia, Yifei, Tang, Puipui, Wei, Bin, Zhang, Qingwen, Wang, Vivien Ya Fan, Yan, Ru. Inhibition and structure-activity relationship of dietary flavones against three Loop 1-type human gut microbial β-glucuronidases[J]. International Journal of Biological Macromolecules, 2022, 220, 1532-1544.
Authors:  Wang, Panpan;  Wu, Rongrong;  Jia, Yifei;  Tang, Puipui;  Wei, Bin; et al.
Favorite | TC[WOS]:9 TC[Scopus]:10  IF:7.7/7.7 | Submit date:2022/12/01
Allosteric Interaction  Flavones  Human Gut Microbial Β-glucuronidases  Inhibitors  Loop 1-type Guss  Structure-activity Relationship  
Discovery of novel anti-tumor compounds targeting PARP-1 with induction of autophagy through in silico and in vitro screening Journal article
Shi, Danfeng, Pang, Qianqian, Qin, Qianyu, Yao, Xinsheng, Yao, Xiaojun, Yu, Yang. Discovery of novel anti-tumor compounds targeting PARP-1 with induction of autophagy through in silico and in vitro screening[J]. Frontiers in Pharmacology, 2022, 13.
Authors:  Shi, Danfeng;  Pang, Qianqian;  Qin, Qianyu;  Yao, Xinsheng;  Yao, Xiaojun; et al.
Favorite | TC[WOS]:3 TC[Scopus]:4  IF:4.4/5.0 | Submit date:2023/01/31
allosteric  anti-tumor  autophagy  in silico screening  PARP-1 inhibitor  
Inhibition and structure-activity relationship of dietary flavones against three Loop 1 human gut microbial β-glucuronidases Journal article
Wang, Panpan, Wu, Rongrong, Jia, Yifei, Tang, Puipui, Zhang, Qingwen, Wang, Yafan, Yan, Ru. Inhibition and structure-activity relationship of dietary flavones against three Loop 1 human gut microbial β-glucuronidases[J]. International Journal of Biological Macromolecules, 2022, 220, 1532-1544.
Authors:  Wang, Panpan;  Wu, Rongrong;  Jia, Yifei;  Tang, Puipui;  Zhang, Qingwen; et al.
Favorite |   IF:7.7/7.7 | Submit date:2022/08/30
Gut Microbial Metabolism  Β-glucuronidases  Gus Inhibitor  Flavones  Structure-activity Relationship  Allosteric Inhibition  
Biased allosteric modulation of formyl peptide receptor 2 leads to distinct receptor conformational states for pro- and anti-inflammatory signaling Journal article
Zhang, Shuo, Gong, Hao, Ge, Yunjun, Ye, Richard D.. Biased allosteric modulation of formyl peptide receptor 2 leads to distinct receptor conformational states for pro- and anti-inflammatory signaling[J]. PHARMACOLOGICAL RESEARCH, 2020, 161, 105117.
Authors:  Zhang, Shuo;  Gong, Hao;  Ge, Yunjun;  Ye, Richard D.
Favorite | TC[WOS]:18 TC[Scopus]:17  IF:9.1/9.0 | Submit date:2021/12/06
g Protein-coupled Receptors  Allosteric Modulation  Inflammation