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Novel Dichloroacetophenone-Based PDHK1 Inhibitors as Potent Anticancer Agents
Journal article
Wu, Puhua, Zhang, Zhicheng, Zhou, Yan, Liu, Quan, Tam, Kin Yip, Su, Zhenhong. Novel Dichloroacetophenone-Based PDHK1 Inhibitors as Potent Anticancer Agents[J]. DRUG DESIGN DEVELOPMENT AND THERAPY, 2024, 18, 4661-4679.
Authors:
Wu, Puhua
;
Zhang, Zhicheng
;
Zhou, Yan
;
Liu, Quan
;
Tam, Kin Yip
; et al.
Favorite
|
TC[WOS]:
0
TC[Scopus]:
0
IF:
4.7
/
4.8
|
Submit date:2024/11/05
Pdhk1
Dichloroacetophenone
Allosteric Pocket
Anti-nsclc Activity
Tumor Xenograft Mouse Model
Inhibition and structure-activity relationship of dietary flavones against three Loop 1-type human gut microbial β-glucuronidases
Journal article
Wang, Panpan, Wu, Rongrong, Jia, Yifei, Tang, Puipui, Wei, Bin, Zhang, Qingwen, Wang, Vivien Ya Fan, Yan, Ru. Inhibition and structure-activity relationship of dietary flavones against three Loop 1-type human gut microbial β-glucuronidases[J]. International Journal of Biological Macromolecules, 2022, 220, 1532-1544.
Authors:
Wang, Panpan
;
Wu, Rongrong
;
Jia, Yifei
;
Tang, Puipui
;
Wei, Bin
; et al.
Favorite
|
TC[WOS]:
9
TC[Scopus]:
10
IF:
7.7
/
7.7
|
Submit date:2022/12/01
Allosteric Interaction
Flavones
Human Gut Microbial Β-glucuronidases
Inhibitors
Loop 1-type Guss
Structure-activity Relationship
Discovery of novel anti-tumor compounds targeting PARP-1 with induction of autophagy through in silico and in vitro screening
Journal article
Shi, Danfeng, Pang, Qianqian, Qin, Qianyu, Yao, Xinsheng, Yao, Xiaojun, Yu, Yang. Discovery of novel anti-tumor compounds targeting PARP-1 with induction of autophagy through in silico and in vitro screening[J]. Frontiers in Pharmacology, 2022, 13.
Authors:
Shi, Danfeng
;
Pang, Qianqian
;
Qin, Qianyu
;
Yao, Xinsheng
;
Yao, Xiaojun
; et al.
Favorite
|
TC[WOS]:
3
TC[Scopus]:
4
IF:
4.4
/
5.0
|
Submit date:2023/01/31
allosteric
anti-tumor
autophagy
in silico screening
PARP-1 inhibitor
Inhibition and structure-activity relationship of dietary flavones against three Loop 1 human gut microbial β-glucuronidases
Journal article
Wang, Panpan, Wu, Rongrong, Jia, Yifei, Tang, Puipui, Zhang, Qingwen, Wang, Yafan, Yan, Ru. Inhibition and structure-activity relationship of dietary flavones against three Loop 1 human gut microbial β-glucuronidases[J]. International Journal of Biological Macromolecules, 2022, 220, 1532-1544.
Authors:
Wang, Panpan
;
Wu, Rongrong
;
Jia, Yifei
;
Tang, Puipui
;
Zhang, Qingwen
; et al.
Favorite
|
IF:
7.7
/
7.7
|
Submit date:2022/08/30
Gut Microbial Metabolism
Β-glucuronidases
Gus Inhibitor
Flavones
Structure-activity Relationship
Allosteric Inhibition
Biased allosteric modulation of formyl peptide receptor 2 leads to distinct receptor conformational states for pro- and anti-inflammatory signaling
Journal article
Zhang, Shuo, Gong, Hao, Ge, Yunjun, Ye, Richard D.. Biased allosteric modulation of formyl peptide receptor 2 leads to distinct receptor conformational states for pro- and anti-inflammatory signaling[J]. PHARMACOLOGICAL RESEARCH, 2020, 161, 105117.
Authors:
Zhang, Shuo
;
Gong, Hao
;
Ge, Yunjun
;
Ye, Richard D.
Favorite
|
TC[WOS]:
18
TC[Scopus]:
17
IF:
9.1
/
9.0
|
Submit date:2021/12/06
g Protein-coupled Receptors
Allosteric Modulation
Inflammation