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Paris saponin VII reverses resistance to PARP inhibitors by regulating ovarian cancer tumor angiogenesis and glycolysis through the RORα/ECM1/VEGFR2 signaling axis. Journal article
Wang MengFei, Yuan ChenYue, Wu Zong, Xu Meng, Chen ZiQi, Yao JiaLiang, Que ZuJun, Tian JianHui, Leung Elaine Lai Han, Wang ZiLiang. Paris saponin VII reverses resistance to PARP inhibitors by regulating ovarian cancer tumor angiogenesis and glycolysis through the RORα/ECM1/VEGFR2 signaling axis.[J]. International Journal of Biological Sciences, 2024, 20(7), 2454-2475.
Authors:  Wang MengFei;  Yuan ChenYue;  Wu Zong;  Xu Meng;  Chen ZiQi; et al.
Adobe PDF | Favorite | TC[WOS]:1 TC[Scopus]:1  IF:8.2/8.3 | Submit date：2024/06/10
Angiogenesis  Ecm1  Glycolysis  Ovarian Cancer  Paris Saponin Vii  Parpi Resistance  Rorα  Vegfr2  
Extracellular Vesicles Maintain Blood-Brain Barrier Integrity by the Suppression of Caveolin-1/CD147/VEGFR2/MMP Pathway After Ischemic Stroke Journal article
Yiyang Li, Jiali Chen, Xingping Quan, Ying Chen, Yan Han, Jinfen Chen, Li Yang, Youhua Xu, Xu Shen, Ruibing Wang, Yonghua Zhao. Extracellular Vesicles Maintain Blood-Brain Barrier Integrity by the Suppression of Caveolin-1/CD147/VEGFR2/MMP Pathway After Ischemic Stroke[J]. International Journal of Nanomedicine, 2024, 19, 1451-1467.
Authors:  Yiyang Li;  Jiali Chen;  Xingping Quan;  Ying Chen;  Yan Han; et al.
Favorite | TC[WOS]:3 TC[Scopus]:2  IF:6.6/7.5 | Submit date：2024/04/03
Cd147  Caveolin-1  Vegfr2  Blood-brain Barrier  Extracellular Vesicles  Ischemic Stroke  Matrix Metalloproteinase  
Murine Beta-Amyloid (1–42) Oligomers Disrupt Endothelial Barrier Integrity and VEGFR Signaling via Activating Astrocytes to Release Deleterious Soluble Factors Journal article
Yue, Qian, Zhou, Xinhua, Zhang, Zaijun, Hoi, Maggie Pui Man. Murine Beta-Amyloid (1–42) Oligomers Disrupt Endothelial Barrier Integrity and VEGFR Signaling via Activating Astrocytes to Release Deleterious Soluble Factors[J]. International Journal of Molecular Sciences, 2022, 23(3), 1878.
Authors:  Yue, Qian;  Zhou, Xinhua;  Zhang, Zaijun;  Hoi, Maggie Pui Man
Favorite | TC[WOS]:9 TC[Scopus]:10 | Submit date：2022/03/04
Astrocytes  Blood–brain Barrier  Endothelial Cells  Murine Amyloid-beta  Tight Junctions  Vegfr2 Signaling Pathway  
A novel bioengineered fragment peptide of Vasostatin-1 exerts smooth muscle pharmacological activities and anti-angiogenic effects via blocking VEGFR signalling pathway Journal article
Wei, Ran, Wu, Qiushuang, Ai, Nana, Wang, Lei, Zhou, Mei, Shaw, Chris, Chen, Tianbao, Ye, Richard Dequan, Ge, Wei, Siu, Shirley W.I., Kwok, Hang Fai. A novel bioengineered fragment peptide of Vasostatin-1 exerts smooth muscle pharmacological activities and anti-angiogenic effects via blocking VEGFR signalling pathway[J]. Computational and Structural Biotechnology Journal, 2021, 19, 2664-2675.
Authors:  Wei, Ran;  Wu, Qiushuang;  Ai, Nana;  Wang, Lei;  Zhou, Mei; et al.
Favorite | TC[WOS]:5 TC[Scopus]:5  IF:4.4/5.0 | Submit date：2021/09/17
Anti-angiogenesis  Chromogranin a  Vasostatin-1  Vegfr2  
Recent advances in structure-based drug design and virtual screening of VEGFR tyrosine kinase inhibitors Journal article
Pui Man Hoi, Shang Li, Chi Teng Vong, Hisa Hui Ling Tseng, Yiu Wa Kwan, Simon Ming-Yuen Lee. Recent advances in structure-based drug design and virtual screening of VEGFR tyrosine kinase inhibitors[J]. Methods, 2015, 71(C), 85-91.
Authors:  Pui Man Hoi;  Shang Li;  Chi Teng Vong;  Hisa Hui Ling Tseng;  Yiu Wa Kwan; et al.
Favorite | TC[WOS]:22 TC[Scopus]:24  IF:4.2/3.8 | Submit date：2018/11/06
Molecular Docking  Pharmacophore Modeling  Vegfr2  Vegfr2 Inhibitors  Virtual Screening  
Resveratrol derivative, trans-3,5,4′-trimethoxystilbene, exerts antiangiogenic and vascular-disrupting effects in zebrafish through the downregulation of VEGFR2 and cell-cycle modulation Journal article
Deepa Alex, Emilia Conceição Leong, Zai-Jun Zhang, Gloria Tse Ho Yan, Shuk-Han Cheng, Chi-Weng Leong, Zhen-Hua Li, Kai-Heng Lam, Shun-Wan Chan, Simon Ming-Yuen Lee. Resveratrol derivative, trans-3,5,4′-trimethoxystilbene, exerts antiangiogenic and vascular-disrupting effects in zebrafish through the downregulation of VEGFR2 and cell-cycle modulation[J]. Journal of Cellular Biochemistry, 2010, 109(2), 339.
Authors:  Deepa Alex;  Emilia Conceição Leong;  Zai-Jun Zhang;  Gloria Tse Ho Yan;  Shuk-Han Cheng; et al.
Favorite | TC[WOS]:54 TC[Scopus]:59 | Submit date：2018/10/30
3,5,4′-trimethoxystilbene  Angiogenesis  Cell Cycle  Huvec  Vegfr2  Zebrafish  
Arylphthalazines as potent, and orally bioavailable inhibitors of VEGFR-2 Journal article
Duncton M.A.J., Piatnitski Chekler E.L., Katoch-Rouse R., Sherman D., Wong W.C., Smith II L.M., Kawakami J.K., Kiselyov A.S., Milligan D.L., Balagtas C., Hadari Y.R., Wang Y., Patel S.N., Rolster R.L., Tonra J.R., Surguladze D., Mitelman S., Kussie P., Bohlen P., Doody J.F.. Arylphthalazines as potent, and orally bioavailable inhibitors of VEGFR-2[J]. Bioorganic and Medicinal Chemistry, 2009, 17(2), 731-740.
Authors:  Duncton M.A.J.;  Piatnitski Chekler E.L.;  Katoch-Rouse R.;  Sherman D.;  Wong W.C.; et al.
Favorite | TC[WOS]:38 TC[Scopus]:38 | Submit date：2019/01/16
Angiogenesis  Arylphthalazine  Inhibitor  Kdr  Kinase  Phthalazine  Vegfr-2