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Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor Journal article
Sun, Yaoliang, Chen, Zhiwen, Liu, Guobin, Chen, Xiaoai, Shi, Zihan, Feng, Huixu, Yu, Lei, Li, Guodong, Ding, Ke, Huang, He, Zhang, Zhang, Xu, Shilin. Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor[J]. Bioorganic Chemistry, 2023, 143, 107053.
Authors:  Sun, Yaoliang;  Chen, Zhiwen;  Liu, Guobin;  Chen, Xiaoai;  Shi, Zihan; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:4.5/4.7 | Submit date：2024/02/22
Cancer  Covalent  Inhibitor  Threonine Tyrosine Kinase (Ttk)  
Down-regulating Nrf2 by tangeretin reverses multiple drug resistance to both chemotherapy and EGFR tyrosine kinase inhibitors in lung cancer Journal article
Xie Ying, Feng SenLing, He Fang, Yan PeiYu, Yao XiaoJun, Fan XingXing, Leung Elaine Lai Han, Zhou Hua. Down-regulating Nrf2 by tangeretin reverses multiple drug resistance to both chemotherapy and EGFR tyrosine kinase inhibitors in lung cancer[J]. PHARMACOLOGICAL RESEARCH, 2022, 186, 106514.
Authors:  Xie Ying;  Feng SenLing;  He Fang;  Yan PeiYu;  Yao XiaoJun; et al.
Favorite | TC[WOS]:18 TC[Scopus]:17  IF:9.1/9.0 | Submit date：2023/01/30
Drug Resistance  Chemotherapy  Egfr Tyrosine Kinase Inhibitors  Nrf2  Tangeretin  
Drug resistance of targeted therapy for advanced non-small cell lung cancer harbored EGFR mutation: from mechanism analysis to clinical strategy Journal article
Yuxin Zhao, Haiyong Wang, Chengwei He. Drug resistance of targeted therapy for advanced non-small cell lung cancer harbored EGFR mutation: from mechanism analysis to clinical strategy[J]. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2021, 147(12), 3653-3664.
Authors:  Yuxin Zhao;  Haiyong Wang;  Chengwei He
Favorite | TC[WOS]:21 TC[Scopus]:20  IF:2.7/3.1 | Submit date：2021/12/08
Non-small Cell Lung Cancer  Targeted Therapy  Epidermal Growth Factor Receptor-tyrosine Kinase Inhibitor  Drug Resistance  
Targeting cd82/kai1 for precision therapeutics in surmounting metastatic potential in breast cancer Review article
2021
Authors:  Viera, Maximillian;  Yip, George Wai Cheong;  Shen, Han Ming;  Baeg, Gyeong Hun;  Bay, Boon Huat
Favorite | TC[WOS]:2 TC[Scopus]:4  IF:4.5/4.9 | Submit date：2021/11/30
Metastasis Suppressor  Tetraspanins  Tyrosine Kinase Inhibitors  Etoposide  Cd82 Mimics  Epigenetic Drugs  
Inhibition of pyruvate dehydrogenase kinase 1 enhances the anti-cancer effect of EGFR tyrosine kinase inhibitors in non-small cell lung cancer Journal article
Yang, Zheng, Zhang, Shao-Lin, Hu, Xiaohui, Tam, Kin Yip. Inhibition of pyruvate dehydrogenase kinase 1 enhances the anti-cancer effect of EGFR tyrosine kinase inhibitors in non-small cell lung cancer[J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 2018, 838, 41-52.
Authors:  Yang, Zheng;  Zhang, Shao-Lin;  Hu, Xiaohui;  Tam, Kin Yip
Favorite | TC[WOS]:27 TC[Scopus]:27  IF:4.2/4.3 | Submit date：2018/10/30
Dichloroacetophenone  Epidermal Growth Factor Receptor  Tyrosine Kinase Inhibitor  Synergism  Hypoxia  Oxidative Phosphorylation  
Prognostic significance of combining VEGFA, FLT1 and KDR mRNA expression in lung cancer Journal article
Zhang S.-D., McCrudden C.M., Kwok H.F.. Prognostic significance of combining VEGFA, FLT1 and KDR mRNA expression in lung cancer[J]. Oncology Letters, 2015, 10(3), 1893-1901.
Authors:  Zhang S.-D.;  McCrudden C.M.;  Kwok H.F.
Favorite | TC[WOS]:21 TC[Scopus]:23 | Submit date：2018/12/19
Angiogenesis  Fms‑related Tyrosine Kinase 1  Kinase Insert Domain Receptor  Lung Cancer  Survival  Vascular Epidermal Growth Factor a  
Sunitinib produces neuroprotective effect via inhibiting nitric oxide overproduction Journal article
Wei Cui, Zai-Jun Zhang, Sheng-Quan Hu, Shing-Hung Mak, Da-Ping Xu, Chung-Lit Choi, Yu-Qiang Wang, Wah-Keung Tsim, Ming-Yuen Lee, Jian-Hui Rong, Yi-Fan Han. Sunitinib produces neuroprotective effect via inhibiting nitric oxide overproduction[J]. CNS Neuroscience and Therapeutics, 2014, 20(3), 244-252.
Authors:  Wei Cui;  Zai-Jun Zhang;  Sheng-Quan Hu;  Shing-Hung Mak;  Da-Ping Xu; et al.
Favorite | TC[WOS]:33 TC[Scopus]:32 | Submit date：2018/11/06
Cancer  Neuroprotection  Nitric Oxide  Nitric Oxide Synthase  Receptor Tyrosine Kinase  Sunitinib  
Chemical constituents from the heartwood of Haematoxylon campechianum as protein tyrosine kinase inhibitors Journal article
Lin L.-G., Xie H., Wang Y.-T., Ding J., Ye Y.. Chemical constituents from the heartwood of Haematoxylon campechianum as protein tyrosine kinase inhibitors[J]. Chemistry and Biodiversity, 2014, 11(5), 776.
Authors:  Lin L.-G.;  Xie H.;  Wang Y.-T.;  Ding J.;  Ye Y.
Favorite | TC[WOS]:12 TC[Scopus]:12 | Submit date：2018/10/31
Epihematoxylol b  Haematoxylon Campechianum  Hematoxylol b, 10-o-methyl-  Homoisoflavonoids  Kinase Insert Domain Receptor (Kdr)  Protein Tyrosine Kinases (Ptks)  
Mutation of the BTK gene and clinical feature of X-linked agammaglobulinemia in mainland China Journal article
Wang Y., Kanegane H., Wang X., Han X., Zhang Q., Zhao S., Yu Y., Wang J., Miyawaki T.. Mutation of the BTK gene and clinical feature of X-linked agammaglobulinemia in mainland China[J]. Journal of Clinical Immunology, 2009, 29(3), 352-356.
Authors:  Wang Y.;  Kanegane H.;  Wang X.;  Han X.;  Zhang Q.; et al.
Favorite | TC[WOS]:25 TC[Scopus]:30 | Submit date：2019/01/16
Bruton's Tyrosine Kinase  Humoral Immunodeficiency  Mutation  X-linked Agammaglobulinemia  
Increased expression of neuronal Src and tyrosine phosphorylation of NMDA receptors in rat brain after systemic treatment with MK-801 Journal article
Linden A.-M., Storvik M., Lakso M., Haapasalo A., Lee D., Witkin J.M., Sei Y., Castren E., Wong G.. Increased expression of neuronal Src and tyrosine phosphorylation of NMDA receptors in rat brain after systemic treatment with MK-801[J]. Neuropharmacology, 2001, 40(4), 469-481.
Authors:  Linden A.-M.;  Storvik M.;  Lakso M.;  Haapasalo A.;  Lee D.; et al.
Favorite | TC[WOS]:8 TC[Scopus]:8 | Submit date：2018/12/18
Cerebral Cortex  Cloning  Dizocilpine  Phencyclidine  Tyrosine Kinase