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Discovery of natural product derivative triptolidiol as a direct NLRP3 inhibitor by reducing K63-specific ubiquitination Journal article
Ding Moyu, Ning Chengqing, Chen Shaoru, Yin Haoran, Xu Jing, WANG YING. Discovery of natural product derivative triptolidiol as a direct NLRP3 inhibitor by reducing K63-specific ubiquitination[J]. doi: 10.1111/bph.17320, 2024, 181(22), 1–18.
Authors:  Ding Moyu;  Ning Chengqing;  Chen Shaoru;  Yin Haoran;  Xu Jing; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:6.8/7.4 | Submit date：2024/10/06
Immunosuppressive Activity  Inflammasome-driven Disease  K63-linked Ubiquitination,  Nlrp3  Triptolide Derivative  Triptolidiol  
Self-Amplified pH/ROS Dual-Responsive Co-Delivery Nano-System with Chemo-Photodynamic Combination Therapy in Hepatic Carcinoma Treatment Journal article
Huang, Yu, Wu, Shuyang, Li, Jingjing, He, Chenglin, Cheng, Yanfen, Li, Nan, Wang, Yitao, Wu, Yihan, Zhang, Jinming. Self-Amplified pH/ROS Dual-Responsive Co-Delivery Nano-System with Chemo-Photodynamic Combination Therapy in Hepatic Carcinoma Treatment[J]. International Journal of Nanomedicine, 2024, 19, 3737-3751.
Authors:  Huang, Yu;  Wu, Shuyang;  Li, Jingjing;  He, Chenglin;  Cheng, Yanfen; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1 | Submit date：2024/05/16
Ce6  Hepatic Carcinoma  Pdt  Ph Responsive  Ros  Triptolide  
pH-sensitive nano-polyelectrolyte complexes with arthritic macrophage-targeting delivery of triptolide Journal article
Jia, Xin Li, Meng, Jiao Zhang, Jin, Feng Shi, Sheng, Peng Wang, Xue, Mei Zhong, Yi, Han Wu, Yan, Qu, Hui, Le Gao, Jin, Ming Zhang. pH-sensitive nano-polyelectrolyte complexes with arthritic macrophage-targeting delivery of triptolide[J]. International Journal of Pharmaceutics, 2023, 632, 122572.
Authors:  Jia, Xin Li;  Meng, Jiao Zhang;  Jin, Feng Shi;  Sheng, Peng Wang;  Xue, Mei Zhong; et al.
Favorite | TC[WOS]:11 TC[Scopus]:9  IF:5.3/5.6 | Submit date：2023/02/22
Triptolide, Polyelectrolyte Complexes  Rheumatoid Arthritis  Macrophage  Pbae  
αvβ3 integrin-specific exosomes engineered with cyclopeptide for targeted delivery of triptolide against malignant melanoma Journal article
Gu, Yongwei, Du, Yue, Jiang, Liangdi, Tang, Xiaomeng, Li, Aixue, Zhao, Yunan, Lang, Yitian, Liu, Xiaoyan, Liu, Jiyong. αvβ3 integrin-specific exosomes engineered with cyclopeptide for targeted delivery of triptolide against malignant melanoma[J]. Journal of Nanobiotechnology, 2022, 20(1).
Authors:  Gu, Yongwei;  Du, Yue;  Jiang, Liangdi;  Tang, Xiaomeng;  Li, Aixue; et al.
Favorite | TC[WOS]:28 TC[Scopus]:29  IF:10.6/11.4 | Submit date：2023/01/30
Crgd  Exosomes  Malignant Melanoma  Targeted Delivery  Triptolide  
A pH-sensitive supramolecular nanosystem with chlorin e6 and triptolide co-delivery for chemo-photodynamic combination therapy Journal article
Wu, Yihan, Li, Jingjing, Zhong, Xuemei, Shi, Jinfeng, Cheng, Yanfen, He, Chenglin, Li, Jiaxin, Zou, Liang, Fu, Chaomei, Chen, Meiwan, Zhang, Jinming, Gao, Huile. A pH-sensitive supramolecular nanosystem with chlorin e6 and triptolide co-delivery for chemo-photodynamic combination therapy[J]. Asian Journal of Pharmaceutical Sciences, 2022, 17(2), 206-218.
Authors:  Wu, Yihan;  Li, Jingjing;  Zhong, Xuemei;  Shi, Jinfeng;  Cheng, Yanfen; et al.
Favorite | TC[WOS]:34 TC[Scopus]:36  IF:10.7/9.0 | Submit date：2022/05/13
Chemo-photodynamic  Co-delivery  Ph-sensitive Supramolecular Nanosystem  Triptolide  
A pH-sensitive supramolecular nanosystem with chlorin e6 and triptolide co-delivery for chemo-photodynamic combination therapy Journal article
Wu, Y., Li, J., Zhong, X., Shi, J., Cheng, Y., He, C., Li, J., Zou, L., Fu, C., Chen, M., Zhang, J., Gao, H.. A pH-sensitive supramolecular nanosystem with chlorin e6 and triptolide co-delivery for chemo-photodynamic combination therapy[J]. Asian Journal of Pharmaceutical Sciences, 2022, N-N.
Authors:  Wu, Y.;  Li, J.;  Zhong, X.;  Shi, J.;  Cheng, Y.; et al.
Favorite |   IF:10.7/9.0 | Submit date：2022/08/29
Triptolide  Chemo-photodynamic  pH-sensitive supramolecular nanosystem  Co-delivery  
Therapeutic potential of triptolide in autoimmune diseases and strategies to reduce its toxicity Journal article
Cheng, Yaxin, Zhao, Yonghua, Zheng, Ying. Therapeutic potential of triptolide in autoimmune diseases and strategies to reduce its toxicity[J]. Chinese Medicine, 2021, 16, 114.
Authors:  Cheng, Yaxin;  Zhao, Yonghua;  Zheng, Ying
Adobe PDF | Favorite | TC[WOS]:32 TC[Scopus]:32  IF:5.3/5.5 | Submit date：2021/12/08
Autoimmune Diseases  Pharmacodynamics  Pharmacology  Toxicity  Triptolide  
Synergistic effect of all-trans-retinal and triptolide encapsulated in an inflammation-targeted nanoparticle on collagen-induced arthritis in mice Journal article
Li,Ping, Yang,Xinyu, Yang,Yang, He,Huamei, Chou,Chon Kit, Chen,Fengyang, Pan,Hong, Liu,Lanlan, Cai,Lintao, Ma,Yifan, Chen,Xin. Synergistic effect of all-trans-retinal and triptolide encapsulated in an inflammation-targeted nanoparticle on collagen-induced arthritis in mice[J]. JOURNAL OF CONTROLLED RELEASE, 2020, 319, 87-103.
Authors:  Li,Ping;  Yang,Xinyu;  Yang,Yang;  He,Huamei;  Chou,Chon Kit; et al.
Favorite | TC[WOS]:60 TC[Scopus]:62  IF:10.5/10.6 | Submit date：2021/03/01
All-trans-retinal  Anti-inflammatory Effect  Galactose Receptor  Rheumatoid Arthritis  Triptolide  
All-trans retinal-conjugated pH-sensitive nanoparticles loaded with triptolide for targeted delivery to inflamed joints Journal article
Li, P., Yang, X., Yang, Y., He, H., Pan, H., Liu, L., Cai, L., Ma, Y., Chen, X.. All-trans retinal-conjugated pH-sensitive nanoparticles loaded with triptolide for targeted delivery to inflamed joints[J]. Journal of Control Release, 2019, 87-103.
Authors:  Li, P.;  Yang, X.;  Yang, Y.;  He, H.;  Pan, H.; et al.
Favorite |  | Submit date：2022/08/30
triptolide  CIA  PD-sensitive nanoparticles  
A Mechanistic Overview of Triptolide and Celastrol, Natural Products from Tripterygium wilfordii Hook F Journal article
Chen, Shao-Ru, Dai, Yan, Zhao, Jing, Lin, Ligen, Wang, Yitao, Wang, Ying. A Mechanistic Overview of Triptolide and Celastrol, Natural Products from Tripterygium wilfordii Hook F[J]. FRONTIERS IN PHARMACOLOGY, 2018, 9.
Authors:  Chen, Shao-Ru;  Dai, Yan;  Zhao, Jing;  Lin, Ligen;  Wang, Yitao; et al.
Favorite | TC[WOS]:249 TC[Scopus]:251  IF:4.4/5.0 | Submit date：2018/10/30
Tripterygium Wilfordii Hook f  Triptolide  Celastrol  Mechanisms Of Action  Structure-activity-relationship