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Probing the AFF4–CCNT1 protein–protein interaction using a metal–organic conjugate for treating triple-negative breast cancer Journal article
Song, Ying Qi, Xu, Yiwen, Yang, Li Jun, Wang, Ling, Jing, Shaozhen, Yang, Guan Jun, Shiu-Hin Chan, Daniel, Wong, Chun Yuen, Wang, Wanhe, Kam Wai Wong, Vincent, Leung, Chung Hang. Probing the AFF4–CCNT1 protein–protein interaction using a metal–organic conjugate for treating triple-negative breast cancer[J]. Chemical Engineering Journal, 2024, 496, 153685.
Authors:  Song, Ying Qi;  Xu, Yiwen;  Yang, Li Jun;  Wang, Ling;  Jing, Shaozhen; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:13.3/13.2 | Submit date：2024/08/05
Aff4  Ccnt1  Metal–organic Conjugate  Protein–protein Interaction  Triple-negative Breast Cancer  
The interaction between macrophages and triple-negative breast cancer cells induces ROS-mediated interleukin 1α expression to enhance tumorigenesis and metastasis Journal article
Meng Hao, Bin Huang,, Renfei Wu, Zheng Peng, Luo, Kathy Qian. The interaction between macrophages and triple-negative breast cancer cells induces ROS-mediated interleukin 1α expression to enhance tumorigenesis and metastasis[J]. Advanced Science, 2023, 10(29), 2302857.
Authors:  Meng Hao;  Bin Huang,;  Renfei Wu;  Zheng Peng;  Luo, Kathy Qian
Favorite | TC[WOS]:5 TC[Scopus]:5  IF:14.3/16.3 | Submit date：2023/08/23
Co-culture  Interleukin 1 Alpha(Il1 Alpha)  Macrophages  Metastasis  Reactive Oxygen Species (Ros)  Triple-negative Breast Cancer (Tnbc)  
Etiological roles of core promoter variation in triple-negative breast cancer Journal article
Huang, Teng, Li, Jiaheng, Wang, San Ming. Etiological roles of core promoter variation in triple-negative breast cancer[J]. Genes & Diseases, 2023, 10(1), 228 - 238.
Authors:  Huang, Teng;  Li, Jiaheng;  Wang, San Ming
Favorite | TC[WOS]:2 TC[Scopus]:3  IF:6.9/7.2 | Submit date：2022/05/17
Core Promoter  Rna-seq  Triple-negative Breast Cancer  Variation  Whole Exome Sequencing  
A tumor-targeted delivery of oral isoliquiritigenin through encapsulated zein phosphatidylcholine hybrid nanoparticles prevents triple-negative breast cancer Journal article
Wang, Yan, Zhang, Chen, Xiao, Meng, Ganesan, Kumar, Gao, Fei, Liu, Qingqing, Ye, Zhen, Sui, Yue, Zhang, Feng, Wei, Kunhua, Wu, Yaobin, Wu, Jianmin, Du, Bing, Xu, Cong, Li, Yan, Li, Peng, Zhang, Jinming, Chen, Jianping. A tumor-targeted delivery of oral isoliquiritigenin through encapsulated zein phosphatidylcholine hybrid nanoparticles prevents triple-negative breast cancer[J]. Journal of Drug Delivery Science and Technology, 2023, 79.
Authors:  Wang, Yan;  Zhang, Chen;  Xiao, Meng;  Ganesan, Kumar;  Gao, Fei; et al.
Favorite | TC[WOS]:12 TC[Scopus]:12  IF:4.5/4.7 | Submit date：2023/02/01
Isoliquiritigenin  Zein-phosphatidylcholine Hybrid Nanoparticles  Bioavailability  Triple-negative Breast Cancer  Safe Therapeutic Strategy  
Single-cell RNA-sequencing uncovers compound kushen injection synergistically improves the efficacy of chemotherapy by modulating the tumor environment of breast cancer Journal article
Liu, Xinkui, Bai, Meirong, Li, Huiying, Ye, Peizhi, Duan, Xiaoxia, Wu, Chao, Huang, Zhihong, Lu, Shan, Zhang, Jingyuan, Zhao, Zihan, Guo, Fengying, You, Rongli, Qin, Wenjie, Wang, Wei, Han, Aiqing, Shen, Liangliang, Wang, Yitao, Zhao, Zheng, Luo, Hua, Wu, Jiarui. Single-cell RNA-sequencing uncovers compound kushen injection synergistically improves the efficacy of chemotherapy by modulating the tumor environment of breast cancer[J]. Frontiers in Immunology, 2022, 13.
Authors:  Liu, Xinkui;  Bai, Meirong;  Li, Huiying;  Ye, Peizhi;  Duan, Xiaoxia; et al.
Favorite | TC[WOS]:6 TC[Scopus]:6  IF:5.7/6.8 | Submit date：2022/12/01
Compound Kushen Injection  Triple-negative Breast Cancer  Single Cell Rna-sequencing  t Lymphocytes  
Cordycepin Inhibits Triple-Negative Breast Cancer Cell Migration and Invasion by Regulating EMT-TFs SLUG, TWIST1, SNAIL1, and ZEB1 Journal article
Wei, Chunli, Khan, Md Asaduzzaman, Du, Jiaman, Cheng, Jingliang, Tania, Mousumi, Elaine Lai-Han Leung, Fu, Junjiang. Cordycepin Inhibits Triple-Negative Breast Cancer Cell Migration and Invasion by Regulating EMT-TFs SLUG, TWIST1, SNAIL1, and ZEB1[J]. Frontiers in Oncology, 2022, 12.
Authors:  Wei, Chunli;  Khan, Md Asaduzzaman;  Du, Jiaman;  Cheng, Jingliang;  Tania, Mousumi; et al.
Favorite | TC[WOS]:25 TC[Scopus]:26  IF:3.5/4.0 | Submit date：2023/01/30
Cancer Therapeutics  Cell Migration And Invasion  Cordycepin  Slug  Triple-negative Breast Cancer (Tnbc)  Twist1  
Toosendanin, a late-stage autophagy inhibitor, sensitizes triple-negative breast cancer to irinotecan chemotherapy Journal article
Zhang, Shuang, Dong, Yu, Chen, Xiuping, Tan, Chris Soon Heng, Li, Min, Miao, Kai, Lu, Jia Hong. Toosendanin, a late-stage autophagy inhibitor, sensitizes triple-negative breast cancer to irinotecan chemotherapy[J]. Chinese Medicine, 2022, 17, 55.
Authors:  Zhang, Shuang;  Dong, Yu;  Chen, Xiuping;  Tan, Chris Soon Heng;  Li, Min; et al.
Favorite | TC[WOS]:11 TC[Scopus]:12  IF:5.3/5.5 | Submit date：2022/05/31
Apoptosis  Autophagy Inhibition  Irinotecan  Lysosome  Sn-38  Toosendanin  Triple-negative Breast Cancer  
Inhibition of the CDK9–cyclin T1 protein–protein interaction as a new approach against triple-negative breast cancer Journal article
Cheng, Sha Sha, Qu, Yuan Qing, Wu, Jia, Yang, Guan Jun, Liu, Hao, Wang, Wanhe, Huang, Qi, Chen, Feng, Li, Guodong, Wong, Chun Yuen, Wong, Vincent Kam Wai, Ma, Dik Lung, Leung, Chung Hang. Inhibition of the CDK9–cyclin T1 protein–protein interaction as a new approach against triple-negative breast cancer[J]. Acta Pharmaceutica Sinica B, 2022, 12(3), 1390-1405.
Authors:  Cheng, Sha Sha;  Qu, Yuan Qing;  Wu, Jia;  Yang, Guan Jun;  Liu, Hao; et al.
Favorite | TC[WOS]:36 TC[Scopus]:39  IF:14.7/14.1 | Submit date：2022/04/06
Epigenetics  Kinase Inhibitor  Metal Complex  Metastasis  Protein–protein Interaction  Triple-negative Breast Cancer  
High Expression of G6PD Increases Doxorubicin Resistance in Triple Negative Breast Cancer Cells by Maintaining GSH Level Journal article
Luo, Man, Fu, Afu, Wu, Renfei, Wei, Na, Song, Kai, Lim, Sierin, Luo, Kathy Qian. High Expression of G6PD Increases Doxorubicin Resistance in Triple Negative Breast Cancer Cells by Maintaining GSH Level[J]. International Journal of Biological Sciences, 2022, 18(3), 1120-1133.
Authors:  Luo, Man;  Fu, Afu;  Wu, Renfei;  Wei, Na;  Song, Kai; et al.
Favorite | TC[WOS]:29 TC[Scopus]:27  IF:8.2/8.3 | Submit date：2022/05/17
Doxorubicin  Drug Resistance  G6pd  Metastasis  Oxidative Stress  Triple Negative Breast Cancer  
Discovery of a tetrahydroisoquinoline-based CDK9-cyclin T1 protein–protein interaction inhibitor as an anti-proliferative and anti-migration agent against triple-negative breast cancer cells Journal article
Shasha Cheng, Guan-Jun Yang, Wanhe Wang, Dik-Lung Ma, Chung-Hang Leung. Discovery of a tetrahydroisoquinoline-based CDK9-cyclin T1 protein–protein interaction inhibitor as an anti-proliferative and anti-migration agent against triple-negative breast cancer cells[J]. Genes & Diseases, 2021, 9(6), 1674-1688.
Authors:  Shasha Cheng;  Guan-Jun Yang;  Wanhe Wang;  Dik-Lung Ma;  Chung-Hang Leung
Favorite | TC[WOS]:23 TC[Scopus]:26  IF:6.9/7.2 | Submit date：2022/05/13
Cancer Stem Cells  Cdk9-cyclin T1  Epithelial Mesenchymal Transition  Protein–protein Interaction (Ppi)  Triple-negative Breast Cancer (Tnbc)