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A natural small molecule aspidosperma-type alkaloid, hecubine, as a new TREM2 activator for alleviating lipopolysaccharide-induced neuroinflammation in vitro and in vivo Journal article
Li, Lin, He, Yu Lin, Xu, Nan, Wang, Xiu Fen, Song, Bing, Tang, Ben Qin, Lee, Simon Ming Yuen. A natural small molecule aspidosperma-type alkaloid, hecubine, as a new TREM2 activator for alleviating lipopolysaccharide-induced neuroinflammation in vitro and in vivo[J]. Redox Biology, 2024, 70, 103057.
Authors:  Li, Lin;  He, Yu Lin;  Xu, Nan;  Wang, Xiu Fen;  Song, Bing; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:10.7/11.7 | Submit date：2024/05/02
Anti-neuroinflammation  Anti-oxidation  Aspidosperma-type Alkaloids  Hecubine  Microglia  Trem2  
TREM2 Deficiency Aggravates NLRP3 Inflammasome Activation and Pyroptosis in MPTP-Induced Parkinson’s Disease Mice and LPS-Induced BV2 Cells Journal article
Huang, Peiting, Zhang, Zhanyu, Zhang, Piao, Feng, Jiezhu, Xie, Jianwei, Zheng, Yinjuan, Liang, Xiaomei, Zhu, Baoyu, Chen, Zhenzhen, Feng, Shujun, Wang, Lijuan, Lu, Jiahong, Liu, Yawei, Zhang, Yuhu. TREM2 Deficiency Aggravates NLRP3 Inflammasome Activation and Pyroptosis in MPTP-Induced Parkinson’s Disease Mice and LPS-Induced BV2 Cells[J]. Molecular Neurobiology, 2023, 61(5), 2590-2605.
Authors:  Huang, Peiting;  Zhang, Zhanyu;  Zhang, Piao;  Feng, Jiezhu;  Xie, Jianwei; et al.
Favorite | TC[WOS]:11 TC[Scopus]:12  IF:4.6/4.7 | Submit date：2024/02/22
Inflammasome  Nlrp3  Parkinson’s Disease  Pyroptosis  Trem2  
IL-4 and IL-10 promotes phagocytic activity of microglia by up-regulation of TREM2 Journal article
Yi, Saini, Jiang, Xue, Tang, Xiaofang, Li, Yahui, Xiao, Chenghong, Zhang, Jinqiang, Zhou, Tao. IL-4 and IL-10 promotes phagocytic activity of microglia by up-regulation of TREM2[J]. Cytotechnology, 2020, 72(4), 589-602.
Authors:  Yi, Saini;  Jiang, Xue;  Tang, Xiaofang;  Li, Yahui;  Xiao, Chenghong; et al.
Favorite | TC[WOS]:25 TC[Scopus]:24  IF:2.0/2.1 | Submit date：2021/12/06
Il-10  Il-4  Microglia  Phagocytosis  Trem2