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β-Carboline Alkaloids From the Deep-Sea Fungus Trichoderma sp. MCCC 3A01244 as a New Type of Anti-pulmonary Fibrosis Agent That Inhibits TGF-β/Smad Signaling Pathway Journal article
Hao, Meng Jiao, Chen, Pei Nan, Li, Hou Jin, Wu, Feng, Zhang, Guang Yu, Shao, Zong Ze, Liu, Xiu Pian, Ma, Wen Zhe, Xu, Jun, Mahmud, Taifo, Lan, Wen Jian. β-Carboline Alkaloids From the Deep-Sea Fungus Trichoderma sp. MCCC 3A01244 as a New Type of Anti-pulmonary Fibrosis Agent That Inhibits TGF-β/Smad Signaling Pathway[J]. Frontiers in Microbiology, 2022, 13.
Authors:  Hao, Meng Jiao;  Chen, Pei Nan;  Li, Hou Jin;  Wu, Feng;  Zhang, Guang Yu; et al.
Favorite | TC[WOS]:14 TC[Scopus]:17  IF:4.0/5.1 | Submit date：2023/01/30
Acid-directed Strategy  Anti-pulmonary Fibrosis  Tgf-β/smad  Trichoderma  Β-carboline Alkaloids  
Nagilactone E suppresses TGF-beta 1-induced epithelial-mesenchymal transition, migration and invasion in non-small cell lung cancer cells Journal article
Le-Le Zhang, Xiao-Ming Jiang, Mu-Yang Huang, Zhe-Ling Feng, Xiuping Chen, Yitao Wang, Hua Li, Ao Li, Li-Gen Lin, Jin-Jian Lu. Nagilactone E suppresses TGF-beta 1-induced epithelial-mesenchymal transition, migration and invasion in non-small cell lung cancer cells[J]. PHYTOMEDICINE, 2019, 52, 32-39.
Authors:  Le-Le Zhang;  Xiao-Ming Jiang;  Mu-Yang Huang;  Zhe-Ling Feng;  Xiuping Chen; et al.
Favorite | TC[WOS]:19 TC[Scopus]:18  IF:6.7/6.2 | Submit date：2020/01/09
Nagilactone e  Tgf-β1  Emt  Smad  
Nagilactone E suppresses TGF-β1-induced epithelial–mesenchymal transition, migration and invasion in non-small cell lung cancer cells Journal article
Le-Le Zhang, Xiao-Ming Jiang, Mu-Yang Huang, Zhe-Ling Feng, Xiuping Chen, Yitao Wang, Hua Li, Ao Li, Li-Gen Lin, Jin-Jian Lu. Nagilactone E suppresses TGF-β1-induced epithelial–mesenchymal transition, migration and invasion in non-small cell lung cancer cells[J]. Phytomedicine, 2019, 32-39.
Authors:  Le-Le Zhang;  Xiao-Ming Jiang;  Mu-Yang Huang;  Zhe-Ling Feng;  Xiuping Chen; et al.
Favorite | TC[WOS]:19 TC[Scopus]:18  IF:6.7/6.2 | Submit date：2022/07/27
Nagilactone e  Tgf-β1  Epithelial-mesenchymal Transition  Smad  
The role of TGF-β/SMAD4 signaling in cancer Journal article
Zhao M., Mishra L., Deng C.-X.. The role of TGF-β/SMAD4 signaling in cancer[J]. International Journal of Biological Sciences, 2018, 14(2), 111-123.
Authors:  Zhao M.;  Mishra L.;  Deng C.-X.
Favorite | TC[WOS]:403 TC[Scopus]:412 | Submit date：2018/12/13
Mouse Model  Prognosis  Smad4  Tgf-β  Tumorigenesis  
The role of TGF-β/SMAD4 signaling in cancer Journal article
Zhao,Ming, Mishra,Lopa, Deng,Chu Xia. The role of TGF-β/SMAD4 signaling in cancer[J]. International Journal of Biological Sciences, 2018, 14(2), 111-123.
Authors:  Zhao,Ming;  Mishra,Lopa;  Deng,Chu Xia
Favorite | TC[WOS]:403 TC[Scopus]:413  IF:8.2/8.3 | Submit date：2020/09/16
Mouse Model  Prognosis  Smad4  Tgf-β  Tumorigenesis  
Pinocembrin from Penthorum chinense Pursh suppresses hepatic stellate cells activation through induction of SIRT3-TGF-β-SMAD signaling axis Conference paper
Zhou, F., Wang, A., Lin, L.. Pinocembrin from Penthorum chinense Pursh suppresses hepatic stellate cells activation through induction of SIRT3-TGF-β-SMAD signaling axis[C], 2017.
Authors:  Zhou, F.;  Wang, A.;  Lin, L.
Favorite |  | Submit date：2022/07/27
Liver fibrosis  Pinocembrin  SIRT3  TGF-β  SMAD  
Tak1, Smad4 and Trim33 redundantly mediate TGF-β3 signaling during palate development Journal article
Lane J., Yumoto K., Azhar M., Ninomiya-Tsuji J., Inagaki M., Hu Y., Deng C.-X., Kim J., Mishina Y., Kaartinen V.. Tak1, Smad4 and Trim33 redundantly mediate TGF-β3 signaling during palate development[J]. Developmental Biology, 2015, 398(2), 231-241.
Authors:  Lane J.;  Yumoto K.;  Azhar M.;  Ninomiya-Tsuji J.;  Inagaki M.; et al.
Favorite | TC[WOS]:34 TC[Scopus]:36 | Submit date：2018/12/13
Palatogenesis  Smad4  Tak1  Tgf-β3 Signaling  Trim33  
3,3′-Diindolylmethane ameliorates experimental hepatic fibrosis via inhibiting miR-21 expression Journal article
Zhang Z., Gao Z., Hu W., Yin S., Wang C., Zang Y., Chen J., Zhang J., Dong L.. 3,3′-Diindolylmethane ameliorates experimental hepatic fibrosis via inhibiting miR-21 expression[J]. British Journal of Pharmacology, 2013, 170(3), 649-660.
Authors:  Zhang Z.;  Gao Z.;  Hu W.;  Yin S.;  Wang C.; et al.
Favorite | TC[WOS]:27 TC[Scopus]:35 | Submit date：2018/11/07
3,3′-diindolylmethane  Ap-1  Hepatic Stellate Cells  Liver Fibrosis  Mir-21  Smad  Tgf-β  
Activation of extracellular signal-regulated kinase by TGF-beta1 via TbetaRII and Smad7 dependent mechanisms in human bronchial epithelial BEP2D cells Journal article
Y.-Y. Huo, Y.-C. Hu, X.-R. He, Y. Wang, B.-Q. Song, P.-K. Zhou, M.-X. Zhu, G. Li, D.-C. Wu. Activation of extracellular signal-regulated kinase by TGF-beta1 via TbetaRII and Smad7 dependent mechanisms in human bronchial epithelial BEP2D cells[J]. CELL BIOLOGY AND TOXICOLOGY, 2007, 23(2), 113-128.
Authors:  Y.-Y. Huo;  Y.-C. Hu;  X.-R. He;  Y. Wang;  B.-Q. Song; et al.
Favorite | TC[WOS]:5 TC[Scopus]:5  IF:5.3/5.3 | Submit date：2019/01/22
Erk1/2  Human Bronchial Epithelial Cells  Smad4  Smad7  Tgf-β1  Tβrii  
Smads orchestrate specific histone modifications and chromatin remodeling to activate transcription Journal article
Ross S., Cheung E., Petrakis T.G., Howell M., Kraus W.L., Hill C.S.. Smads orchestrate specific histone modifications and chromatin remodeling to activate transcription[J]. EMBO Journal, 2006, 25(19), 4490-4502.
Authors:  Ross S.;  Cheung E.;  Petrakis T.G.;  Howell M.;  Kraus W.L.; et al.
Favorite | TC[WOS]:122 TC[Scopus]:128 | Submit date：2018/12/17
Brg1  Chromatin  Smad  Tgf-β  Transcription