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Computer-driven formulation development of Ginsenoside Rh2 ternary solid dispersion Journal article
Lu, Tianshu, Wu, Tongchuan, Zhong, Hao, Li, Xue, Zhang, Yunsen, Yue, Hao, Dai, Yulin, Li, Haifeng, Ouyang, Defang. Computer-driven formulation development of Ginsenoside Rh2 ternary solid dispersion[J]. Drug Delivery and Translational Research, 2024.
Authors:  Lu, Tianshu;  Wu, Tongchuan;  Zhong, Hao;  Li, Xue;  Zhang, Yunsen; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:5.7/5.5 | Submit date：2024/07/04
(20s)-ginsenoside Rh2  Dissolution Rate  Gelucire 44/14  Molecular Dynamics Simulation  Ternary Solid Dispersion  
The applications of machine learning to predict the forming of chemically stable amorphous solid dispersions prepared by hot-melt extrusion Journal article
Jiang, Junhuang, Lu, Anqi, Ma, Xiangyu, Ouyang, Defang, Williams, Robert O.. The applications of machine learning to predict the forming of chemically stable amorphous solid dispersions prepared by hot-melt extrusion[J]. International Journal of Pharmaceutics-X, 2023, 5, 100164.
Authors:  Jiang, Junhuang;  Lu, Anqi;  Ma, Xiangyu;  Ouyang, Defang;  Williams, Robert O.
Favorite | TC[WOS]:11 TC[Scopus]:12 | Submit date：2023/02/28
Amorphous Solid Dispersion  Artificial Intelligence  Hot-melt Extrusion  Machine Learning  
PharmSD: A novel AI-based computational platform for solid dispersion formulation design Journal article
Dong, Jie, Gao, Hanlu, Ouyang, Defang. PharmSD: A novel AI-based computational platform for solid dispersion formulation design[J]. International Journal of Pharmaceutics, 2021, 604, 120705.
Authors:  Dong, Jie;  Gao, Hanlu;  Ouyang, Defang
Favorite | TC[WOS]:20 TC[Scopus]:23  IF:5.3/5.6 | Submit date：2021/12/08
Computational Platform  Drug Design  Formulation  Machine Learning  Solid Dispersion  Web Server  
Using Acetone/Water Binary Solvent to Enhance the Stability and Bioavailability of Spray Dried Enzalutamide/HPMC-AS Solid Dispersions Journal article
Zhang,Xiaoting, Rao,Qiuhong, Qiu,Zhenwen, Lin,Yisheng, Zhang,Lei, Hu,Qingzhong, Chen,Tingting, Ma,Zhimin, Gao,Hanlu, Luo,Dandong, Zhao,Jiaqi, Ouyang,Defang, Zhang,Zhenyu Jason, Li,Qingguo. Using Acetone/Water Binary Solvent to Enhance the Stability and Bioavailability of Spray Dried Enzalutamide/HPMC-AS Solid Dispersions[J]. Journal of Pharmaceutical Sciences, 2021, 110(3), 1160-1171.
Authors:  Zhang,Xiaoting;  Rao,Qiuhong;  Qiu,Zhenwen;  Lin,Yisheng;  Zhang,Lei; et al.
Favorite | TC[WOS]:11 TC[Scopus]:12  IF:3.7/3.5 | Submit date：2021/03/02
Amorphous Solid Dispersion  Drug-excipient Interaction  Particle Size  Poorly Water-soluble Drug  Spray Drying  
An integrated computational methodology with data-driven machine learning, molecular modeling and PBPK modeling to accelerate solid dispersion formulation design Journal article
Gao,Hanlu, Wang,Wei, Dong,Jie, Ye,Zhuyifan, Ouyang,Defang. An integrated computational methodology with data-driven machine learning, molecular modeling and PBPK modeling to accelerate solid dispersion formulation design[J]. European Journal of Pharmaceutics and Biopharmaceutics, 2021, 158, 336-346.
Authors:  Gao,Hanlu;  Wang,Wei;  Dong,Jie;  Ye,Zhuyifan;  Ouyang,Defang
Favorite | TC[WOS]:35 TC[Scopus]:46  IF:4.4/4.8 | Submit date：2021/03/02
Dissolution Profile  Machine Learning  Molecular Dynamics (Md) Simulations  Pharmacokinetic Modeling  Solid Dispersion  
Simultaneous extraction, separation, isolation and identification of endogenous components from Etlingera elatior by pressurized matrix solid-phase dispersion using liquid chromatography–mass spectrometry Journal article
Ge,Liya, Yong,Jean Wan Hong, Tan,Swee Ngin, Li,Shao Ping. Simultaneous extraction, separation, isolation and identification of endogenous components from Etlingera elatior by pressurized matrix solid-phase dispersion using liquid chromatography–mass spectrometry[J]. Journal of Chromatography A, 2020, 1611, 460604.
Authors:  Ge,Liya;  Yong,Jean Wan Hong;  Tan,Swee Ngin;  Li,Shao Ping
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:3.8/3.5 | Submit date：2021/03/01
Etlingera Elatior  Lc–ms  Nmr  Pressurized Matrix Solid-phase Dispersion  Sample Preparation  
Insight into the Dissolution Molecular Mechanism of Ternary Solid Dispersions by Combined Experiments and Molecular Simulations Journal article
Han, R., Huang, T., Liu, X., Yin, X., Li, H., Lu, J., Ji, Y., Sun, H., Ouyang, D.. Insight into the Dissolution Molecular Mechanism of Ternary Solid Dispersions by Combined Experiments and Molecular Simulations[J]. AAPS PharmSciTech, 2019, 274-274.
Authors:  Han, R.;  Huang, T.;  Liu, X.;  Yin, X.;  Li, H.; et al.
Favorite |   IF:3.4/3.5 | Submit date：2022/08/11
dissolution effect  molecular modeling  solid dispersion  ternary system  
Predicting physical stability of solid dispersions by machine learning techniques Journal article
Han,Run, Xiong,Hui, Ye,Zhuyifan, Yang,Yilong, Huang,Tianhe, Jing,Qiufang, Lu,Jiahong, Pan,Hao, Ren,Fuzheng, Ouyang,Defang. Predicting physical stability of solid dispersions by machine learning techniques[J]. Journal of Controlled Release, 2019, 311, 16-25.
Authors:  Han,Run;  Xiong,Hui;  Ye,Zhuyifan;  Yang,Yilong;  Huang,Tianhe; et al.
Favorite | TC[WOS]:89 TC[Scopus]:104  IF:10.5/10.6 | Submit date：2021/03/02
Machine Learning  Molecular Modeling  Physical Stability  Solid Dispersion  
Insight into the Dissolution Molecular Mechanism of Ternary Solid Dispersions by Combined Experiments and Molecular Simulations Journal article
Run Han, Tianhe Huang, Xinyang Liu, Xinyang Liu, Haifeng Li, Jiahong Lu, Yuanhui Ji, Huimin Sun, Defang Ouyang. Insight into the Dissolution Molecular Mechanism of Ternary Solid Dispersions by Combined Experiments and Molecular Simulations[J]. AAPS PHARMSCITECH, 2019, 20(7).
Authors:  Run Han;  Tianhe Huang;  Xinyang Liu;  Xinyang Liu;  Haifeng Li; et al.
Favorite | TC[WOS]:14 TC[Scopus]:16  IF:3.4/3.5 | Submit date：2020/03/25
Solid Dispersion  Dissolution Effect  Molecular Modeling  Ternary System  
Analysis of the Literature and Patents on Solid Dispersions from 1980 to 2015 Journal article
Zhang, Jinglu, Han, Run, Chen, Weijie, Zhang, Weixiang, Li, Ying, Ji, Yuanhui, Chen, Lijiang, Pan, Hao, Yang, Xinggang, Pan, Weisan, Ouyang, Defang. Analysis of the Literature and Patents on Solid Dispersions from 1980 to 2015[J]. MOLECULES, 2018, 23(7).
Authors:  Zhang, Jinglu;  Han, Run;  Chen, Weijie;  Zhang, Weixiang;  Li, Ying; et al.
Favorite | TC[WOS]:39 TC[Scopus]:39  IF:4.2/4.6 | Submit date：2018/10/30
Solid Dispersion  Big Data  Literature  Patent  Scientific Knowledge Mapping  Citespace