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Sanggenon g, a diels-alder adduct screened from mori cortex, attenuated irinotecan-induced gastrointestinal toxicity in mice through suppressing sn-38 intestinal accumulation via a dual inhibition mechanism. Conference proceedings
Prague, 2023-09
Authors:  YAN RU
Favorite |  | Submit date：2024/08/29
Gus Inhibitor  Sanggenon g  Diels-alder Adduct  Irinotecan-induced Toxicity  Oatp2b1 Inhibitor  Sn-38  
Fecal microbial SN-38G metabotypes in colorectal cancer patients are associated with irinotecan-induced delayed diarrhea Conference paper
Wu, Rongrong, Chen, Junru, Jia, Yifei, Chen, Yijia, Li, Yang, YAN RU. Fecal microbial SN-38G metabotypes in colorectal cancer patients are associated with irinotecan-induced delayed diarrhea[C], 2023.
Authors:  Wu, Rongrong;  Chen, Junru;  Jia, Yifei;  Chen, Yijia;  Li, Yang; et al.
Favorite |  | Submit date：2024/08/31
Sn-38g Metabotypes  Fecal Microbial Metabolism  Colorectal Cancer  Irinotecan-induced Delayed Diarrhea  Gut Microbial Β-glucuronidases  
The correlation between gut microbial SN-38G metabotypes and irinotecan-induced gastrointestinal toxicity in colorectal cancer patients Conference proceedings
Beijing, May 18-22, 2023
Authors:  Wu, Rongrong;  YAN RU
Favorite |  | Submit date：2023/08/30
Gut Microbiota  Sn-38g Metabotypes  Irinotecan  Gastrointestinal Toxicity  Colorectal Cancer  
Fecal microbial SN-38G metabotypes in colorectal cancer patients are associated with irinotecan-induced gastrointestinal toxicity. Conference proceedings
Macao, Dec 2-4, 2022
Authors:  Wu, Rongrong;  Chen, Junru;  Jia, Yifei;  Chen, Yijia;  Yan, Ru
Favorite |  | Submit date：2023/05/20
Sn-38g Metabotypes  Colorectal Cancer  Irinotecan  Gastrointestinal Toxicity  Gut Microbiota  Beta-glucuronidases  
Fecal microbial SN-38G metabotypes in colorectal cancer patients are associated with irinotecan-induced gastrointestinal toxicity Conference proceedings
Dec 2-4, 2022
Authors:  Wu, Rongrong;  YAN RU
Favorite |  | Submit date：2023/08/31
Gut Microbiota  Sn-38g Metabotypes  Irinotecan-induced Gastrointestinal Toxicity.  Colorectal Cancer  
Toosendanin, a late-stage autophagy inhibitor, sensitizes triple-negative breast cancer to irinotecan chemotherapy Journal article
Zhang, Shuang, Dong, Yu, Chen, Xiuping, Tan, Chris Soon Heng, Li, Min, Miao, Kai, Lu, Jia Hong. Toosendanin, a late-stage autophagy inhibitor, sensitizes triple-negative breast cancer to irinotecan chemotherapy[J]. Chinese Medicine, 2022, 17, 55.
Authors:  Zhang, Shuang;  Dong, Yu;  Chen, Xiuping;  Tan, Chris Soon Heng;  Li, Min; et al.
Favorite | TC[WOS]:11 TC[Scopus]:12  IF:5.3/5.5 | Submit date：2022/05/31
Apoptosis  Autophagy Inhibition  Irinotecan  Lysosome  Sn-38  Toosendanin  Triple-negative Breast Cancer  
Combination Inhibition of Gut Microbial β-Glucuronidase Metabolism and Intestinal Uptake by MSK Attenuated Irinotecan-induced Gastrointestinal Toxicity in Mice Conference proceedings
Authors:  Wang, Panpan;  Hou, Tingting;  Wu, Rongrong;  Yan, Ru
Favorite |  | Submit date：2022/08/15
Β-glucuronidases  Combination Inhibition  Gut Microbial Metabolism  Irinotecan  Gastrointestinal Toxicity  Intestinal Uptake  Sn-38g  Mori Cortex  Da Adducts