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Bioactivity-based molecular networking-guided identification of guttiferone J from Garcinia cambogia as an anti-obesity candidate Journal article
Feng, Zheling, Chen, Jiali, Chen, Cheng, Feng, Lu, Wang, Rui, Zhu, Jianzhong, Lou, Ruohan, Liu, Jia, Ye, Yang, Lin, Ligen. Bioactivity-based molecular networking-guided identification of guttiferone J from Garcinia cambogia as an anti-obesity candidate[J]. British Journal of Pharmacology, 2022, 180(5), 589-608.
Authors:  Feng, Zheling;  Chen, Jiali;  Chen, Cheng;  Feng, Lu;  Wang, Rui; et al.
Favorite | TC[WOS]:9 TC[Scopus]:10  IF:6.8/7.4 | Submit date：2023/04/03
Anti-obesity  Bioactivity-based Molecular Networking  Garcinia Cambogia  Guttiferone j  Sirtuin 3  White Adipose Tissue Browning  
14-Deoxygarcinol improves insulin sensitivity in high-fat diet-induced obese mice via mitigating NF-κB/Sirtuin 2-NLRP3-mediated adipose tissue remodeling Journal article
Jia-li Chen, Zhe-ling Feng, Fei Zhou, Ruo-han Lou, Cheng Peng, Yang Ye, Li-gen Lin. 14-Deoxygarcinol improves insulin sensitivity in high-fat diet-induced obese mice via mitigating NF-κB/Sirtuin 2-NLRP3-mediated adipose tissue remodeling[J]. Acta Pharmacologica Sinica, 2022, 44, 434–445.
Authors:  Jia-li Chen;  Zhe-ling Feng;  Fei Zhou;  Ruo-han Lou;  Cheng Peng; et al.
Favorite | TC[WOS]:10 TC[Scopus]:10  IF:6.9/7.6 | Submit date：2023/01/30
14-deoxygarcinol  Adipose Tissue Inflammation  Insulin Resistance  Interleukin-1β  Nlrp3 Inflammasome  Sirtuin 2  
Berberine remodels adipose tissue to attenuate metabolic disorders by activating sirtuin 3 Journal article
Li, Dan, Yang, Chao, Zhu, Jian zhong, Lopez, Eduardo, Zhang, Tian, Tong, Qiang, Peng, Cheng, Lin, Li gen. Berberine remodels adipose tissue to attenuate metabolic disorders by activating sirtuin 3[J]. ACTA PHARMACOLOGICA SINICA, 2022, 43(5), 1285-1298.
Authors:  Li, Dan;  Yang, Chao;  Zhu, Jian zhong;  Lopez, Eduardo;  Zhang, Tian; et al.
Favorite | TC[WOS]:38 TC[Scopus]:42  IF:6.9/7.6 | Submit date：2022/05/13
Adipose Tissue Inflammation  Berberine  Fibrosis  Insulin Resistance  Liver Injury  Sirtuin 3  
Ainsliadimer C, a disesquiterpenoid isolated from Ainsliaea macrocephala, ameliorates inflammatory responses in adipose tissue via Sirtuin 1-NLRP3 inflammasome axis Journal article
Chen, Cheng, Ren, Yong mei, Zhu, Jian zhong, Chen, Jia li, Feng, Zhe ling, Zhang, Tian, Ye, Yang, Lin, Li gen. Ainsliadimer C, a disesquiterpenoid isolated from Ainsliaea macrocephala, ameliorates inflammatory responses in adipose tissue via Sirtuin 1-NLRP3 inflammasome axis[J]. ACTA PHARMACOLOGICA SINICA, 2021, 43(8), 1780-1792.
Authors:  Chen, Cheng;  Ren, Yong mei;  Zhu, Jian zhong;  Chen, Jia li;  Feng, Zhe ling; et al.
Favorite | TC[WOS]:16 TC[Scopus]:16  IF:6.9/7.6 | Submit date：2022/05/13
Adipose Tissue Inflammation  Ainsliadimer c  Dexamethasone  Ex-527  Interleukin-1β  Macrophages  Metabolic Disorders  Nlrp3 Inflammasome  Obesity  Sirtuin 1  
SIRT3 acts as a positive autophagy regulator to promote lipid mobilization in adipocytes via activating AMPK Journal article
Zhang,Tian, Liu,Jingxin, Tong,Qiang, Lin,Ligen. SIRT3 acts as a positive autophagy regulator to promote lipid mobilization in adipocytes via activating AMPK[J]. International Journal of Molecular Sciences, 2020, 21(2), 372.
Authors:  Zhang,Tian;  Liu,Jingxin;  Tong,Qiang;  Lin,Ligen
Favorite | TC[WOS]:50 TC[Scopus]:51  IF:4.9/5.6 | Submit date：2021/03/01
Ampk  Chaperone-mediated Autophagy  Lipid Metabolism  Macroautophagy  Sirtuin 3  
γ-Mangostin alleviates liver fibrosis through Sirtuin 3-superoxide-high mobility group box 1 signaling axis Journal article
Anqi Wang, Fayang Zhou, Dan Li, Jin-Jian Lu, Yitao Wang, Ligen Lin. γ-Mangostin alleviates liver fibrosis through Sirtuin 3-superoxide-high mobility group box 1 signaling axis[J]. Toxicology and Applied Pharmacology, 2019, 363, 142-153.
Authors:  Anqi Wang;  Fayang Zhou;  Dan Li;  Jin-Jian Lu;  Yitao Wang; et al.
Favorite | TC[WOS]:21 TC[Scopus]:24  IF:3.3/3.6 | Submit date：2018/12/28
Fibrogenesis  Hmgb1  Liver Fibrosis  Sirtuin 3  Superoxide  Γ-mangostin