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Atavistic strategy for the treatment of hyperuricemia via ionizable liposomal mRNA Journal article
Zhang, Mengjie, Hussain, Abid, Hu, Bo, Yang, Haiyin, Li, Chunhui, Guo, Shuai, Han, Xiaofeng, Li, Bei, Dai, Yunlu, Cao, Yuhong, Chi, Hang, Weng, Yuhua, Qin, Cheng Feng, Huang, Yuanyu. Atavistic strategy for the treatment of hyperuricemia via ionizable liposomal mRNA[J]. Nature Communications, 2024, 15(1), 6463.
Authors:  Zhang, Mengjie;  Hussain, Abid;  Hu, Bo;  Yang, Haiyin;  Li, Chunhui; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:14.7/16.1 | Submit date：2024/09/03
Serum Uric-acid  Urate Oxidase  Delivery  Sirna  Risk  Endocytosis  Therapy  
Delivery of therapeutic small interfering RNA: The current patent-based landscape Journal article
Chen, Yu, Xiong, Shi Hang, Li, Fei, Kong, Xiang Jun, Ouyang, De Fang, Zheng, Ying, Yu, Hua, Hu, Yuan Jia. Delivery of therapeutic small interfering RNA: The current patent-based landscape[J]. Molecular Therapy - Nucleic Acids, 2022, 29, 150-161.
Authors:  Chen, Yu;  Xiong, Shi Hang;  Li, Fei;  Kong, Xiang Jun;  Ouyang, De Fang; et al.
Favorite | TC[WOS]:4 TC[Scopus]:6  IF:6.5/6.7 | Submit date：2023/06/29
Delivery Technology  Patent Landscape  Therapeutic Sirna  
Acid-activatible micelleplex delivering siRNA-PD-L1 for improved cancer immunotherapy of CDK4/6 inhibition Journal article
Gao, Jing, Zhang, Hanwu, Zhou, Fengqi, Hou, Bo, Chen, Meiwan, Xie, Zhigang, Yu, Haijun. Acid-activatible micelleplex delivering siRNA-PD-L1 for improved cancer immunotherapy of CDK4/6 inhibition[J]. Chinese Chemical Letters, 2021, 32(6), 1929-1936.
Authors:  Gao, Jing;  Zhang, Hanwu;  Zhou, Fengqi;  Hou, Bo;  Chen, Meiwan; et al.
Favorite | TC[WOS]:35 TC[Scopus]:34  IF:9.4/7.3 | Submit date：2021/12/08
Acid-activatible Micelleplex  Cancer Immunotherapy  Cdk4/6 Inhibitor  Pd-l1 Knockdown  Sirna Delivery  
Hydrotalcite intercalated siRNA: Computational characterization of the interlayer environment Journal article
Zhang H., Ouyang D., Murthy V., Wong Y., Xu Z., Smith S.C.. Hydrotalcite intercalated siRNA: Computational characterization of the interlayer environment[J]. Pharmaceutics, 2012, 4(2), 296-313.
Authors:  Zhang H.;  Ouyang D.;  Murthy V.;  Wong Y.;  Xu Z.; et al.
Favorite | TC[Scopus]:8 | Submit date：2019/01/15
Gene Therapy  Layered Double Hydroxide  Molecular Dynamics Simulations  Sirna Delivery  
The effect of pH on PAMAM dendrimer-siRNA complexation - Endosomal considerations as determined by molecular dynamics simulation Journal article
Ouyang D., Zhang H., Parekh H.S., Smith S.C.. The effect of pH on PAMAM dendrimer-siRNA complexation - Endosomal considerations as determined by molecular dynamics simulation[J]. Biophysical Chemistry, 2011, 158(2-3), 126-133.
Authors:  Ouyang D.;  Zhang H.;  Parekh H.S.;  Smith S.C.
Favorite | TC[WOS]:76 TC[Scopus]:81 | Submit date：2019/01/15
Dendrimer  Endosome  Gene Delivery  Molecular Dynamics Simulation  Proton Sponge Theory  Sirna