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Ras inhibitor farnesylthiosalicylic acid conjugated with IR783 dye exhibits improved tumor-targeting and altered anti-breast cancer mechanisms in mice
Journal article
Huang, Qiu ju, Liao, Guo chao, Zhuang, Xue rong, Yang, Meng lan, Yao, Jing jing, Deng, Jian hua, Zhang, Yan min, Wang, Ying, Qi, Xiao xiao, Pan, Dong feng, Guan, Yang, Huang, Zhi ying, Zhang, Feng xue, Liu, Zhong qiu, Lu, Lin lin. Ras inhibitor farnesylthiosalicylic acid conjugated with IR783 dye exhibits improved tumor-targeting and altered anti-breast cancer mechanisms in mice[J]. Acta Pharmacologica Sinica, 2022, 43(7), 1843-1856.
Authors:
Huang, Qiu ju
;
Liao, Guo chao
;
Zhuang, Xue rong
;
Yang, Meng lan
;
Yao, Jing jing
; et al.
Favorite
|
TC[WOS]:
4
TC[Scopus]:
3
IF:
6.9
/
7.6
|
Submit date:2023/01/30
Ampk
Breast Neoplasm
Farnesylthiosalicylic Acid
Ir783
Mtor
Ras Inhibitor
Tumor-targeting
RSU-1 interaction with prohibitin-2 links cell–extracellular matrix detachment to downregulation of ERK signaling
Journal article
Wang, Meiling, Liu, Jie, Tu, Yizeng, Zhao, Zihan, Qu, Jingjing, Chen, Ka, Chen, Yonglong, Sun, Ying, Zhao, Hui, Deng, Yi, Wu, Chuanyue. RSU-1 interaction with prohibitin-2 links cell–extracellular matrix detachment to downregulation of ERK signaling[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 296, 100109.
Authors:
Wang, Meiling
;
Liu, Jie
;
Tu, Yizeng
;
Zhao, Zihan
;
Qu, Jingjing
; et al.
Favorite
|
TC[Scopus]:
4
IF:
4.0
/
4.4
|
Submit date:2021/12/07
Ras Suppressor 1 (Rsu1)
Extracellular Signal–regulated Kinase (Erk)
Prohibitin (Phb)
Extracellular Matrix (Ecm)
Integrin
Lipid Rafts
Targeting RNA helicase DHX33 blocks Ras-driven lung tumorigenesis in vivo
Journal article
Wang,Xingshun, Feng,Weimin, Peng,Cheng, Chen,Shiyun, Ji,Hongbin, Zhong,Hanbing, Ge,Wei, Zhang,Yandong. Targeting RNA helicase DHX33 blocks Ras-driven lung tumorigenesis in vivo[J]. CANCER SCIENCE, 2020, 111(10), 3564-3575.
Authors:
Wang,Xingshun
;
Feng,Weimin
;
Peng,Cheng
;
Chen,Shiyun
;
Ji,Hongbin
; et al.
Favorite
|
TC[WOS]:
10
TC[Scopus]:
10
IF:
4.5
/
5.5
|
Submit date:2021/03/02
Dhx33
Lung Cancer
Oncogene
Ras
Rna Helicase
The Application of Ferroptosis in Diseases
Review article
2020
Authors:
Qiu, Yangmin
;
Cao, Yue
;
Cao, Wangjia
;
Jia, Yifei
;
Lu, Na
Favorite
|
TC[WOS]:
272
TC[Scopus]:
285
IF:
9.1
/
9.0
|
Submit date:2021/12/06
Cancer
Cell Death
Deferasirox (Pubchem Cid: 214348)
Deferoxamine (Pubchem Cid: 2973)
Erastin (Pubchem Cid: 11214940)
Ferroptosis
Ferrostatin-1 (Pubchem Cid: 4068248)
Iron Metabolism
Lapatinib (Pubchem Cid: 208908)
Lipid Peroxidation
Ras-selective Lethal 3 (Pubchem Cid: 1750826)
Reactive Oxygen Species
Sorafenib (Pubchem Cid: 216239)
RSU-1 maintains integrity of caenorhabditis elegans vulval muscles by regulating a-actinin
Journal article
Wang,Xinyan, Huang,Shuai, Zheng,Cunni, Ge,Wei, Wu,Chuanyue, Tse,Yu Chung. RSU-1 maintains integrity of caenorhabditis elegans vulval muscles by regulating a-actinin[J]. G3: Genes, Genomes, Genetics, 2020, 10(7), 2507-2517.
Authors:
Wang,Xinyan
;
Huang,Shuai
;
Zheng,Cunni
;
Ge,Wei
;
Wu,Chuanyue
; et al.
Favorite
|
TC[WOS]:
3
TC[Scopus]:
3
IF:
2.1
/
2.5
|
Submit date:2021/03/02
A-actinin
Egg-laying
Ras
Rsu-1
Vulval Muscle Cells
Activation of ras-dependent signaling pathways by G14-coupled receptors requires the adaptor protein TPR1
Journal article
Kwan D.H.T., Yung L.Y., Ye R.D., Wong Y.H.. Activation of ras-dependent signaling pathways by G14-coupled receptors requires the adaptor protein TPR1[J]. Journal of Cellular Biochemistry, 2012, 113(11), 3486-3497.
Authors:
Kwan D.H.T.
;
Yung L.Y.
;
Ye R.D.
;
Wong Y.H.
Favorite
|
TC[WOS]:
10
TC[Scopus]:
11
|
Submit date:2018/11/07
Erk
Gα14
Ikk
Plcβ
Ras
Tpr1
Gα16 activates Ras by forming a complex with tetratricopeptide repeat 1 (TPR1) and Son of Sevenless (SOS)
Journal article
Liu A.M.F., Lo R.K.H., Lee M.M.K., Wang Y., Yeung W.W.S., Ho M.K.C., Su Y., Ye R.D., Wong Y.H.. Gα16 activates Ras by forming a complex with tetratricopeptide repeat 1 (TPR1) and Son of Sevenless (SOS)[J]. Cellular Signalling, 2010, 22(10), 1448-1458.
Authors:
Liu A.M.F.
;
Lo R.K.H.
;
Lee M.M.K.
;
Wang Y.
;
Yeung W.W.S.
; et al.
Favorite
|
TC[WOS]:
16
TC[Scopus]:
16
|
Submit date:2018/11/07
g Protein
Ras
Signal Transduction
Tpr1
Regulation of RASSF1A in nasopharyngeal cells and its response to UV irradiation
Journal article
Lee V.H.Y., Chow B.K.C., Lo K.W., Chow L.S.N., Man C., Tsao S.W., Lee L.T.O.. Regulation of RASSF1A in nasopharyngeal cells and its response to UV irradiation[J]. Gene, 2009, 443(1-2), 55-63.
Authors:
Lee V.H.Y.
;
Chow B.K.C.
;
Lo K.W.
;
Chow L.S.N.
;
Man C.
; et al.
Favorite
|
TC[WOS]:
7
TC[Scopus]:
8
|
Submit date:2019/01/15
Nasopharyngeal Carcinoma
Promoter
Ras-association Domain Family 1 a (Rassf1a)
Sp-proteins