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Design, synthesis and antitumor evaluation of novel 1H-indole-2-carboxylic acid derivatives targeting 14-3-3η protein
Journal article
Gao, Zhenxiong, Fan, Tingting, Chen, Linbo, Yang, Mengchu, Wai Wong, Vincent Kam, Chen, Dawei, Liu, Zijian, Zhou, Yaoyao, Wu, Weibin, Qiu, Zixuan, Zhang, Cunlong, Li, Yuan, Jiang, Yuyang. Design, synthesis and antitumor evaluation of novel 1H-indole-2-carboxylic acid derivatives targeting 14-3-3η protein[J]. European Journal of Medicinal Chemistry, 2022, 238.
Authors:
Gao, Zhenxiong
;
Fan, Tingting
;
Chen, Linbo
;
Yang, Mengchu
;
Wai Wong, Vincent Kam
; et al.
Favorite
|
TC[WOS]:
3
TC[Scopus]:
3
IF:
6.0
/
6.1
|
Submit date:2023/01/30
14-3-3η Protein
Antitumor Bioactivity
Drug Design
Hepatocellular Carcinoma
Novel Target
Xihuang pills induce apoptosis in hepatocellular carcinoma by suppressing phosphoinositide 3-kinase/protein kinase-B/mechanistic target of rapamycin pathway
Journal article
Teng, Yong Jie, Deng, Zhe, Ouyang, Zhao Guang, Zhou, Qing, Mei, Si, Fan, Xing Xing, Wu, Yong Rong, Long, Hong Ping, Fang, Le Yao, Yin, Dong Liang, Zhang, Bo Yu, Guo, Yin Mei, Zhu, Wen Hao, Huang, Zhen, Zheng, Piao, Ning, Di Min, Tian, Xue Fei. Xihuang pills induce apoptosis in hepatocellular carcinoma by suppressing phosphoinositide 3-kinase/protein kinase-B/mechanistic target of rapamycin pathway[J]. World Journal of Gastrointestinal Oncology, 2022, 14(4), 872-886.
Authors:
Teng, Yong Jie
;
Deng, Zhe
;
Ouyang, Zhao Guang
;
Zhou, Qing
;
Mei, Si
; et al.
Favorite
|
TC[WOS]:
5
TC[Scopus]:
6
IF:
2.5
/
2.8
|
Submit date:2023/01/30
Antitumour
Apoptosis
Hepatocellular Carcinoma
Phosphoinositide 3-kinase/protein Kinase-b/mechanistic Target Of Rapamycin Pathway
Xihuang Pills
Development and application of novel electrophilic warheads in target identification and drug discovery
Review article
2021
Authors:
Liu, Yue
;
Lv, Shumin
;
Peng, Lijie
;
Xie, Chengliang
;
Gao, Liqian
; et al.
Favorite
|
TC[WOS]:
21
TC[Scopus]:
22
IF:
5.3
/
5.2
|
Submit date:2021/12/08
Activity-based Protein Profiling
Amino Acid Residues
Covalent Inhibitors
Electrophilic Warhead
Protein Target
Amino acids regulate energy utilization through mammalian target of rapamycin complex 1 and adenosine monophosphate activated protein kinase pathway in porcine enterocytes
Journal article
Xiao, Hao, Zha, Cuifang, Shao, Fangyuan, Wang, Li, Tan, Bi'e. Amino acids regulate energy utilization through mammalian target of rapamycin complex 1 and adenosine monophosphate activated protein kinase pathway in porcine enterocytes[J]. Animal Nutrition, 2020, 6(1), 98-106.
Authors:
Xiao, Hao
;
Zha, Cuifang
;
Shao, Fangyuan
;
Wang, Li
;
Tan, Bi'e
Favorite
|
TC[WOS]:
8
TC[Scopus]:
10
|
Submit date:2021/12/06
Adenosine Monophosphate Activated Protein Kinase
Amino Acids
Energy Utilization
Mammalian Target Of Rapamycin
Mitochondrial Respiration
Optimizing CRISPR/Cas9 technology for precise correction of the Fgfr3-Gly374Arg mutation in achondroplasia in mice
Journal article
Kai Miao, Xin Zhang, Sek Man Su, Jianming Zeng, Zebin Huang, Un In Chan, Xiaoling Xu, Chu-Xia Deng. Optimizing CRISPR/Cas9 technology for precise correction of the Fgfr3-Gly374Arg mutation in achondroplasia in mice[J]. The Journal of Biological Chemistry, 2018.
Authors:
Kai Miao
;
Xin Zhang
;
Sek Man Su
;
Jianming Zeng
;
Zebin Huang
; et al.
Favorite
|
TC[WOS]:
10
TC[Scopus]:
11
IF:
4.0
/
4.4
|
Submit date:2018/12/17
Fgfr3
Crispr/cas9
Protein
Targeted Correction
Off-target
Achondroplasia
Dwarfism
Genome Editing
Gene Therapy
Effects of straw leachates from Cry1C-expressing transgenic rice on the development and reproduction of Daphnia magna
Journal article
Yi Chen, Yanjie Gao, Haojun Zhu, Jörg Romeis, Yunhe Li, Yufa Peng, Xiuping Chen. Effects of straw leachates from Cry1C-expressing transgenic rice on the development and reproduction of Daphnia magna[J]. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2018, 165, 630-636.
Authors:
Yi Chen
;
Yanjie Gao
;
Haojun Zhu
;
Jörg Romeis
;
Yunhe Li
; et al.
Favorite
|
TC[WOS]:
4
TC[Scopus]:
6
IF:
6.2
/
6.3
|
Submit date:2020/01/09
Bt Protein
Environmental Risk Assessment
Non-target Effect
Daphnia Magna
Chronic Toxicit
Catalase