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Metabolic characterization of (±)-praeruptorin A in vitro and in vivo by high performance liquid chromatography coupled with hybrid triple quadrupole-linear ion trap mass spectrometry and time-of-flight mass spectrometry Journal article
Song, Yue-Lin, Jing, Wang-Hui, Yan, Ru, Wang, Yi-Tao. Metabolic characterization of (±)-praeruptorin A in vitro and in vivo by high performance liquid chromatography coupled with hybrid triple quadrupole-linear ion trap mass spectrometry and time-of-flight mass spectrometry[J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2014, 90(5), 98-110.
Authors:  Song, Yue-Lin;  Jing, Wang-Hui;  Yan, Ru;  Wang, Yi-Tao
View | Adobe PDF | Favorite | TC[WOS]:25 TC[Scopus]:25  IF:3.1/3.1 | Submit date：2018/11/01
(+/-)-praeruptorin a  Metabolism  Lightsight (Tm) Software  In Vivo  Peucedani Radix  
H-1 nuclear magnetic resonance based-metabolomic characterization of Peucedani Radix and simultaneous determination of praeruptorin A and praeruptorin B Journal article
Song, Yue-Lin, Jing, Wang-Hui, Chen, Yan-Gan, Yuan, Yun-Fei, Yan, Ru, Wang, Yi-Tao. H-1 nuclear magnetic resonance based-metabolomic characterization of Peucedani Radix and simultaneous determination of praeruptorin A and praeruptorin B[J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2014, 93(SI), 86-94.
Authors:  Song, Yue-Lin;  Jing, Wang-Hui;  Chen, Yan-Gan;  Yuan, Yun-Fei;  Yan, Ru; et al.
View | Adobe PDF | Favorite | TC[WOS]:27 TC[Scopus]:28  IF:3.1/3.1 | Submit date：2018/11/01
Peucedani Radix  Metabolomic Profile  Quantitative H-1 Nmr  Praeruptorin a  Praeruptorin b  
Simultaneously enantiospecific determination of (+)-trans-khellactone, ( plus /-)-praeruptorin A, ( plus /-)-praeruptorin B, (+)-praeruptorin E, and their metabolites, ( plus /-)-cis-khellactone, in rat plasma using online solid phase extraction-chiral LC-MS/MS Journal article
Yuelin Songa, Wanghui Jinga, Fengqing Yang, Zhan Shi, Meicun Yao, Ru Yan, Yitao Wang. Simultaneously enantiospecific determination of (+)-trans-khellactone, ( plus /-)-praeruptorin A, ( plus /-)-praeruptorin B, (+)-praeruptorin E, and their metabolites, ( plus /-)-cis-khellactone, in rat plasma using online solid phase extraction-chiral LC-MS/MS[J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2014, 0731-7085, 269-277.
Authors:  Yuelin Songa;  Wanghui Jinga;  Fengqing Yang;  Zhan Shi;  Meicun Yao; et al.
Favorite | TC[WOS]:36 TC[Scopus]:37  IF:3.1/3.1 | Submit date：2020/03/26
Pharmacokinetics  Online Spe  Chiral Lc–ms/ms  Enantioselectivity  Peucedani Radix  ( + /-)-praeruptorin a  ( + /-)-praeruptorin b  (+)-praeruptorin e  
1H nuclear magnetic resonance based-metabolomic characterization of Peucedani Radix and simultaneous determination of praeruptorin A and praeruptorin B Journal article
Song Y.-L., Jing W.-H., Chen Y.-G., Yuan Y.-F., Yan R., Wang Y.-T.. 1H nuclear magnetic resonance based-metabolomic characterization of Peucedani Radix and simultaneous determination of praeruptorin A and praeruptorin B[J]. Journal of Pharmaceutical and Biomedical Analysis, 2014, 93, 86-94.
Authors:  Song Y.-L.;  Jing W.-H.;  Chen Y.-G.;  Yuan Y.-F.;  Yan R.; et al.
Favorite | TC[WOS]:27 TC[Scopus]:28 | Submit date：2018/11/06
Metabolomic Profile  Peucedani Radix  Praeruptorin a  Praeruptorin b  
1H nuclear magnetic resonance based-metabolomic characterization of Peucedani Radix and simultaneous determination of praeruptorin A and praeruptorin B Journal article
Song Y.-L., Jing W.-H., Chen Y.-G., Yuan Y.-F., Yan R., Wang Y.-T.. 1H nuclear magnetic resonance based-metabolomic characterization of Peucedani Radix and simultaneous determination of praeruptorin A and praeruptorin B[J]. Journal of Pharmaceutical and Biomedical Analysis, 2014, 93, 86-94.
Authors:  Song Y.-L.;  Jing W.-H.;  Chen Y.-G.;  Yuan Y.-F.;  Yan R.; et al.
Favorite | TC[WOS]:27 TC[Scopus]:28 | Submit date：2018/12/28
Metabolomic Profile  Peucedani Radix  Praeruptorin a  Praeruptorin b  
Regulation of human pregnane X receptor and its target gene cytochrome P450 3A by praeruptorin a isolated from the herbal medicine peucedanum praeruptorum Journal article
Huang L., Bi H.-C., Li Y.-H., Zhang J.-Q., Kuang S.-Y., Zhang L., Wang Y.-T., Huang M.. Regulation of human pregnane X receptor and its target gene cytochrome P450 3A by praeruptorin a isolated from the herbal medicine peucedanum praeruptorum[J]. Planta Medica, 2013, 79(16), 1509-1515.
Authors:  Huang L.;  Bi H.-C.;  Li Y.-H.;  Zhang J.-Q.;  Kuang S.-Y.; et al.
Favorite | TC[WOS]:6 TC[Scopus]:6 | Submit date：2018/11/06
Apiaceae  Cytochrome P450 3a  Herb-drug Interaction  Peucedanum Praeruptorum  Praeruptorin a  Pregnane x Receptor  
Up-regulatation of CYP3A expression through pregnent X receptor by praeruptorin D isolated from Peucedanum praeruptorum Dunn Journal article
Huang L., Huang M., Li Y.-H., Li R.-M., Zeng Y., Kuang S.-Y., Zhang L., Wang Y.-T., Bi H.-C.. Up-regulatation of CYP3A expression through pregnent X receptor by praeruptorin D isolated from Peucedanum praeruptorum Dunn[J]. Journal of Ethnopharmacology, 2013, 148(2), 596.
Authors:  Huang L.;  Huang M.;  Li Y.-H.;  Li R.-M.;  Zeng Y.; et al.
Favorite | TC[WOS]:17 TC[Scopus]:16 | Submit date：2018/10/30
Praeruptorin d Pregnane x Receptor (Pxr) Cytochrome P450 3a Induction Herb-drug Interaction  
Identification of cytochrome P450 isoenzymes involved in metabolism of (+)-praeruptorin A, a calcium channel blocker, by human liver microsomes using ultra high-performance liquid chromatography coupl Journal article
Jing, Wang-Hui, Song, Yue-Lin, Yan, Ru, Wang, Yi-Tao. Identification of cytochrome P450 isoenzymes involved in metabolism of (+)-praeruptorin A, a calcium channel blocker, by human liver microsomes using ultra high-performance liquid chromatography coupl[J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2013, 77, 175-188.
Authors:  Jing, Wang-Hui;  Song, Yue-Lin;  Yan, Ru;  Wang, Yi-Tao
Favorite | TC[WOS]:19 TC[Scopus]:18  IF:3.1/3.1 | Submit date：2018/11/01
Angular-type Pyranocoumarins  (+)-praeruptorin a  Uhplc–qt-ms/ms  Human Liver Microsomes  Cyp 3a4  
Identification of cytochrome P450 isoenzymes involved in metabolism of (+)-praeruptorin A, a calcium channel blocker, by human liver microsomes using ultra high-performance liquid chromatography coupled with tandem mass spectrometry Journal article
Jing W.-H., Song Y.-L., Yan R., Wang Y.-T.. Identification of cytochrome P450 isoenzymes involved in metabolism of (+)-praeruptorin A, a calcium channel blocker, by human liver microsomes using ultra high-performance liquid chromatography coupled with tandem mass spectrometry[J]. Journal of Pharmaceutical and Biomedical Analysis, 2013, 77, 175.
Authors:  Jing W.-H.;  Song Y.-L.;  Yan R.;  Wang Y.-T.
Favorite | TC[WOS]:19 TC[Scopus]:18  IF:3.1/3.1 | Submit date：2018/10/31
(+)-praeruptorin a  Angular-type Pyranocoumarins  Cytochrome Cyp 3a4  Metabolism  Human Liver Microsomes  Uhplc-qt-ms/ms  Chinese Medicines  Peucedani Radix  
Transport and metabolism of (±)-praeruptorin A in Caco-2 cell monolayers Journal article
Jing W.H., Song Y.L., Yan R., Bi H.C., Li P.T., Wang Y.T.. Transport and metabolism of (±)-praeruptorin A in Caco-2 cell monolayers[J]. Xenobiotica, 2011, 41(1), 71.
Authors:  Jing W.H.;  Song Y.L.;  Yan R.;  Bi H.C.;  Li P.T.; et al.
Favorite | TC[WOS]:20 TC[Scopus]:21  IF:1.3/1.4 | Submit date：2018/10/31
(±)-praeruptorin a  Caco-2 Cells  Enantioselectivity  Hydrolysis  Metabolism  Transport