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Novel C. elegans models of Lewy body disease reveal pathological protein interactions and widespread miRNA dysregulation Journal article
Li, Rongzhen, Huang, Xiaobing, Shen, Linjing, Zhang, Tianjiao, Liu, Ning, Hou, Xiangqing, Wong, Garry. Novel C. elegans models of Lewy body disease reveal pathological protein interactions and widespread miRNA dysregulation[J]. Cellular and Molecular Life Sciences, 2024, 81(1), 377.
Authors:  Li, Rongzhen;  Huang, Xiaobing;  Shen, Linjing;  Zhang, Tianjiao;  Liu, Ning; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:6.2/7.7 | Submit date：2024/10/10
Amyloid β  Parkinson’s Disease  Tar-dna-binding Protein 43  Tau Protein  Α-synuclein  
Oxyphylla A exerts antiparkinsonian effects by ameliorating 6-OHDA-induced mitochondrial dysfunction and dyskinesia in vitro and in vivo Journal article
Shao, Min, Zhao, Chen, Pan, Zhijian, Yang, Xuanjun, Gao, Cheng, Kam, Gloria Hio Cheng, Zhou, Hefeng, Lee, Simon Ming Yuen. Oxyphylla A exerts antiparkinsonian effects by ameliorating 6-OHDA-induced mitochondrial dysfunction and dyskinesia in vitro and in vivo[J]. Chemico-Biological Interactions, 2024, 403, 111224.
Authors:  Shao, Min;  Zhao, Chen;  Pan, Zhijian;  Yang, Xuanjun;  Gao, Cheng; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.7/4.6 | Submit date：2024/10/10
6-ohda  Mitochondria  Neuroprotection  Oxyphylla a  Parkinson's Disease  Target Prediction  
Tetramethylpyrazine nitrone exerts neuroprotection via activation of PGC-1α/Nrf2 pathway in Parkinson's disease models Journal article
Guo, Baojian, Zheng, Chengyou, Cao, Jie, Luo, Fangcheng, Li, Haitao, Hu, Shengquan, Mingyuan Lee, Simon, Yang, Xifei, Zhang, Gaoxiao, Zhang, Zaijun, Sun, Yewei, Wang, Yuqiang. Tetramethylpyrazine nitrone exerts neuroprotection via activation of PGC-1α/Nrf2 pathway in Parkinson's disease models[J]. Journal of Advanced Research, 2024, 64, 195-211.
Authors:  Guo, Baojian;  Zheng, Chengyou;  Cao, Jie;  Luo, Fangcheng;  Li, Haitao; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:11.4/11.0 | Submit date：2024/02/22
Nuclear Factor Erythroid-2-related Factor 2  Parkinson's Disease  Peroxisome Proliferator-activated Receptor γ Co-activator 1α  Tetramethylpyrazine Nitrone  
Deep-Learning-Based Cross-Modality Striatum Segmentation for Dopamine Transporter SPECT in Parkinson’s Disease Journal article
Haiyan Wang, Han Jiang, Gefei Chen, Yu Du, Zhonglin Lu, Zhanli Hu,, MOK SENG PENG. Deep-Learning-Based Cross-Modality Striatum Segmentation for Dopamine Transporter SPECT in Parkinson’s Disease[J]. IEEE Transactions on Radiation and Plasma Medical Sciences, 2024, 8(7), 752-761.
Authors:  Haiyan Wang;  Han Jiang;  Gefei Chen;  Yu Du;  Zhonglin Lu; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:4.6/3.6 | Submit date：2024/08/08
Cross-modality  Deep Learning (Dl)  Parkinson’s Disease (Pd)  Spect  Striatum Segmentation  
Rasagiline Exerts Neuroprotection towards Oxygen–Glucose-Deprivation/Reoxygenation-Induced GAPDH-Mediated Cell Death by Activating Akt/Nrf2 Signaling Journal article
Lecht, Shimon, Lahiani, Adi, Klazas, Michal, Naamneh, Majdi Saleem, Rubin, Limor, Dong, Jiayi, Zheng, Wenhua, Lazarovici, Philip. Rasagiline Exerts Neuroprotection towards Oxygen–Glucose-Deprivation/Reoxygenation-Induced GAPDH-Mediated Cell Death by Activating Akt/Nrf2 Signaling[J]. Biomedicines, 2024, 12(7), 1592.
Authors:  Lecht, Shimon;  Lahiani, Adi;  Klazas, Michal;  Naamneh, Majdi Saleem;  Rubin, Limor; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:3.9/4.1 | Submit date：2024/08/05
Akt  Cell Death  Gapdh  Ischemia-like Insult  Neuroprotection  Nrf2  Phosphorylation  Rasagiline  Ros  Pc 12 Neuronal Model  Α-synuclein  Parkinson’s Disease  Stroke  
Radiomics incorporating deep features for predicting Parkinson’s disease in 123I-Ioflupane SPECT Journal article
Jiang, Han, Du, Yu, Lu, Zhonglin, Wang, Bingjie, Zhao, Yonghua, Wang, Ruibing, Zhang, Hong, Mok, Greta S.P.. Radiomics incorporating deep features for predicting Parkinson’s disease in 123I-Ioflupane SPECT[J]. EJNMMI Physics, 2024, 11(1), 60.
Authors:  Jiang, Han;  Du, Yu;  Lu, Zhonglin;  Wang, Bingjie;  Zhao, Yonghua; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:3.0/3.7 | Submit date：2024/08/05
123i-ioflupane  Deep Feature  Deep Learning  Parkinson’s Disease  Radiomics  Spect  
Tetramethylpyrazine Nitrone Promotes the Clearance of Alpha-Synuclein via Nrf2-Mediated Ubiquitin–Proteasome System Activation Journal article
Guo, Baojian, Zheng, Chengyou, Cao, Jie, Qiu, Xiaoling, Luo, Fangcheng, Li, Haitao, Lee, Simon Mingyuan, Yang, Xifei, Zhang, Gaoxiao, Sun, Yewei, Zhang, Zaijun, Wang, Yuqiang. Tetramethylpyrazine Nitrone Promotes the Clearance of Alpha-Synuclein via Nrf2-Mediated Ubiquitin–Proteasome System Activation[J]. NeuroMolecular Medicine, 2024, 26(1), 9.
Authors:  Guo, Baojian;  Zheng, Chengyou;  Cao, Jie;  Qiu, Xiaoling;  Luo, Fangcheng; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:3.3/3.6 | Submit date：2024/05/16
Nuclear Factor Erythroid-2-related Factor 2  Parkinson’s Disease  Peroxisome Proliferator-activated Receptor γ Co-activator 1α  Tetramethylpyrazine Nitrone  Ubiquitin–proteasome System  Α-synuclein  
J24335 exerts neuroprotective effects against 6-hydroxydopamine-induced lesions in PC12 cells and mice Journal article
Pan, Zhijian, Shao, Min, Zhao, Chen, Yang, Xuanjun, Li, Haitao, Cui, Guozhen, Liang, Xiaonan, Yu, Chao Wu, Ye, Qingqing, Gao, Cheng, Di, Lijun, Chern, Ji Wang, Zhou, Hefeng, Lee, Simon Ming Yuen. J24335 exerts neuroprotective effects against 6-hydroxydopamine-induced lesions in PC12 cells and mice[J]. European Journal of Pharmaceutical Sciences, 2024, 194, 106696.
Authors:  Pan, Zhijian;  Shao, Min;  Zhao, Chen;  Yang, Xuanjun;  Li, Haitao; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.3/4.2 | Submit date：2024/04/02
6-ohda  J24335  Mitochondria Dysfunction  Neurotoxicity  Parkinson's Disease  Target Prediction  
Downregulation of Ambra1 by altered DNA methylation exacerbates dopaminergic neuron damage in a fenpropathrin-induced Parkinson-like mouse model Journal article
He, Songzhe, Qu, Qi, Chen, Xi, Zhao, Li, Jiao, Zhigang, Wan, Zhiting, Kwok, Hang Fai, Qu, Shaogang. Downregulation of Ambra1 by altered DNA methylation exacerbates dopaminergic neuron damage in a fenpropathrin-induced Parkinson-like mouse model[J]. Ecotoxicology and Environmental Safety, 2024, 271, 115995.
Authors:  He, Songzhe;  Qu, Qi;  Chen, Xi;  Zhao, Li;  Jiao, Zhigang; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:6.2/6.3 | Submit date：2024/02/22
Ambra1  Dopaminergic Neuron  Fenpropathrin  Mitophagy  Parkinson's Disease  
Antagonizing pathological α-synuclein-mediated neurodegeneration by J24335 via the activation of immunoproteasome Journal article
Pan, Zhijian, Yu, Chao Wu, Zhao, Chen, Shao, Min, Yang, Xuanjun, Liang, Xiaonan, Li, Haitao, Lu, Yucong, Ye, Qingqing, Chern, Ji Wang, Lu, Jiahong, Zhou, Hefeng, Lee, Simon Ming Yuen. Antagonizing pathological α-synuclein-mediated neurodegeneration by J24335 via the activation of immunoproteasome[J]. Toxicology and Applied Pharmacology, 2023, 480, 116745.
Authors:  Pan, Zhijian;  Yu, Chao Wu;  Zhao, Chen;  Shao, Min;  Yang, Xuanjun; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:3.3/3.6 | Submit date：2024/01/02
Immunoproteasome  J24335  Lmp7  Parkinson's Disease  Protein Degradation  Α-synuclein