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Small molecule α-methylene-γ-butyrolactone, an evolutionarily conserved moiety in sesquiterpene lactones, ameliorates arthritic phenotype via interference DNA binding activity of NF-κB Journal article
Linghu, Kegang, Cui, Wenqing, Li, Taiqin, Tuo, Yueting, Wang, Dasong, Pan, Huiqi, Zhang, Tian, Lin, Ligen, Yu, Hua, Hu, Xiaoxia, Li, Haiyang, Shen, Xiangchun. Small molecule α-methylene-γ-butyrolactone, an evolutionarily conserved moiety in sesquiterpene lactones, ameliorates arthritic phenotype via interference DNA binding activity of NF-κB[J]. Acta Pharmaceutica Sinica B, 2024, 14(8), 3561-3575.
Authors:  Linghu, Kegang;  Cui, Wenqing;  Li, Taiqin;  Tuo, Yueting;  Wang, Dasong; et al.
Favorite | TC[WOS]:3 TC[Scopus]:4  IF:14.7/14.1 | Submit date：2024/05/16
A-methylene-g-  Butyrolactone  Rheumatoid Arthritis  Nf-kb P65  Synovial  Microenvironment  Sesquiterpene Lactones  
Oxyimperatorin attenuates LPS-induced microglial activation in vitro and in vivo via suppressing NF-κB p65 signaling Journal article
Lu, Changcheng, Huang, Chen, Qu, Shuhui, Lin, Huiyuan, Zhong, Hai Jing, Chong, Cheong Meng. Oxyimperatorin attenuates LPS-induced microglial activation in vitro and in vivo via suppressing NF-κB p65 signaling[J]. Biomedicine and Pharmacotherapy, 2024, 173, 116379.
Authors:  Lu, Changcheng;  Huang, Chen;  Qu, Shuhui;  Lin, Huiyuan;  Zhong, Hai Jing; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:6.9/6.8 | Submit date：2024/05/02
Microglia  Neuroinflammation  Nf-κb P65  Oxyimperatorin  Pro-inflammatory Cytokines  
Leocarpinolide B Attenuates Collagen Type II-Induced Arthritis by Inhibiting DNA Binding Activity of NF-κB Journal article
Linghu, Ke Gang, Zhao, Guan Ding, Zhang, Dai Yan, Xiong, Shi Hang, Wu, Guo Ping, Shen, Li Yu, Cui, Wen Qing, Zhang, Tian, Hu, Yuan Jia, Guo, Bing, Shen, Xiang Chun, Yu, Hua. Leocarpinolide B Attenuates Collagen Type II-Induced Arthritis by Inhibiting DNA Binding Activity of NF-κB[J]. Molecules (Basel, Switzerland), 2023, 28(10), 4241.
Authors:  Linghu, Ke Gang;  Zhao, Guan Ding;  Zhang, Dai Yan;  Xiong, Shi Hang;  Wu, Guo Ping; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:4.2/4.6 | Submit date：2023/06/05
Leocarpinolide b  Nf-κb P65  Rheumatoid Arthritis  Sesquiterpene Lactone  Synovitis  
Neferine Suppresses Experimental Colitis-Associated Colorectal Cancer by Inhibition of NF-KB p65 and STAT3 Journal article
Yishan Zhou, Shuangli Xiang, Haoyi Zheng, Ying Hou, Ying Wang, Chuang-Chuang Li, Qin Wu, Jingshan Shi, Xiuping Chen. Neferine Suppresses Experimental Colitis-Associated Colorectal Cancer by Inhibition of NF-KB p65 and STAT3[J]. American Journal of Chinese Medicine, 2022, 50(5), 1387-1400.
Authors:  Yishan Zhou;  Shuangli Xiang;  Haoyi Zheng;  Ying Hou;  Ying Wang; et al.
Favorite | TC[WOS]:2 TC[Scopus]:4  IF:4.8/5.0 | Submit date：2022/07/28
Neferine  Colitis-associated Colorectal Cancer  Nf-κb P65  Stat3  
Therapeutic potential of isobavachalcone, a natural flavonoid, in murine experimental colitis by inhibiting NF-κB p65 Journal article
Zhou, Yishan, Zhong, Bingling, Min, Xiangjing, Hou, Ying, Lin, Ligen, Wu, Qin, Shi, Jingshan, Chen, Xiuping. Therapeutic potential of isobavachalcone, a natural flavonoid, in murine experimental colitis by inhibiting NF-κB p65[J]. Phytotherapy Research, 2021, 35(10), 5861-5870.
Authors:  Zhou, Yishan;  Zhong, Bingling;  Min, Xiangjing;  Hou, Ying;  Lin, Ligen; et al.
Favorite | TC[WOS]:21 TC[Scopus]:22  IF:6.1/7.0 | Submit date：2021/12/08
Inflammation  Isobavachalcone  Nf-κb P65  Ulcerative Colitis  
Neuroprotective effects of the andrographolide analogue AL-1 in the MPP+/MPTP-induced Parkinson's disease model in vitro and in mice Journal article
Zaijun Zhang, Daoxu Lai, Liang Wang, Pei Yu, Longjun Zhu, Baojian Guo, Lipeng Xu, Libing Zhou, Yewei Sun, Simon Ming Yuen Lee, Yuqiang Wang. Neuroprotective effects of the andrographolide analogue AL-1 in the MPP+/MPTP-induced Parkinson's disease model in vitro and in mice[J]. Pharmacology Biochemistry and Behavior, 2014, 122, 191-202.
Authors:  Zaijun Zhang;  Daoxu Lai;  Liang Wang;  Pei Yu;  Longjun Zhu; et al.
Favorite | TC[WOS]:37 TC[Scopus]:43 | Submit date：2018/11/06
Andrographolide-lipoic Acid Conjugate  Neuroprotection  Nf-κb P65  Parkinson's Disease  
Involvement of NF‐κB subunit p65 and retinoic acid receptors, RARα and RXRα, in transcriptional regulation of the human GnRH II gene Journal article
Ruby L. C. Hoo, Kathy Y. Y. Chan, Francis K. Y. Leung, Leo T. O. Lee, Peter C. K. Leung, Billy K. C. Chow. Involvement of NF‐κB subunit p65 and retinoic acid receptors, RARα and RXRα, in transcriptional regulation of the human GnRH II gene[J]. FEBS Journal, 2007, 274(11), 2695-2706.
Authors:  Ruby L. C. Hoo;  Kathy Y. Y. Chan;  Francis K. Y. Leung;  Leo T. O. Lee;  Peter C. K. Leung; et al.
Favorite | TC[WOS]:14 TC[Scopus]:15  IF:5.5/5.5 | Submit date：2019/01/28
Gonadotropin-releasing Hormone Ii  Nf-κb Subunit P65  Retinoic Acid Receptors  Silencer  Transcriptional Regulation