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Artemisinin protected human bronchial epithelial cells from amiodarone-induced oxidative damage via 5′-AMP-activated protein kinase (AMPK) activation Journal article
Yang, Chao, Xiong, Wenjun, Dong, Jiayi, Zhao, Xia, Liang, Guang, Zheng, Wenhua. Artemisinin protected human bronchial epithelial cells from amiodarone-induced oxidative damage via 5′-AMP-activated protein kinase (AMPK) activation[J]. Redox Report, 2025, 30(1), 2447721.
Authors:  Yang, Chao;  Xiong, Wenjun;  Dong, Jiayi;  Zhao, Xia;  Liang, Guang; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:5.2/4.9 | Submit date：2025/01/22
Amiodarone  ‌pulmonary Toxicity  Artemisinin  Beas-2b Cells  Oxidative Stress  Apoptosis‌  Ampk  Nrf2‌  
Tetramethylpyrazine Analogue T-006 Protects Neuronal and Endothelial Cells Against Oxidative Stress via PI3K/AKT/mTOR and Nrf2 Signaling Journal article
Zhang, Guiliang, Liang, Zirong, Wang, Yuqiang, Zhang, Zaijun, Hoi, Pui Man. Tetramethylpyrazine Analogue T-006 Protects Neuronal and Endothelial Cells Against Oxidative Stress via PI3K/AKT/mTOR and Nrf2 Signaling[J]. Antioxidants, 2024, 13(10), 1272.
Authors:  Zhang, Guiliang;  Liang, Zirong;  Wang, Yuqiang;  Zhang, Zaijun;  Hoi, Pui Man
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:6.0/6.7 | Submit date：2024/12/05
Tetramethylpyrazine Analogue T-006  Oxidative Cytotoxicity  Excessive Glutamate  Ogd/r  Pi3k/akt  Nrf2/ho-1  Mtor  
Ganweikang extract protects hepatocytes from oxidative injury by activating Nrf2/HO-1 and MAPKs pathways Journal article
Xiao Linxuan, Zhao Mingming, Linghu Ke-Gang, Wu Guoping, Zhang Tian, Chen Chengyu, Guan Jianli, Cao Zhiming, HU YUANJIA, Yu Hua. Ganweikang extract protects hepatocytes from oxidative injury by activating Nrf2/HO-1 and MAPKs pathways[J]. Fitoterapia, 2024, 178, 106146.
Authors:  Xiao Linxuan;  Zhao Mingming;  Linghu Ke-Gang;  Wu Guoping;  Zhang Tian; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:2.5/2.7 | Submit date：2024/08/29
Ganweikang  Acute Hepatic Injury  Hepato-protection  Nrf2/ho-1  Mapks  
Artemisinin inhibits neuronal ferroptosis in Alzheimer's disease models by targeting KEAP1 Journal article
Peng-xi Deng, Marta Silva, Na Yang, Qing Wang, Xin Meng, Ke-qiang Ye, Hong-chang Gao, ZHENG WENHUA. Artemisinin inhibits neuronal ferroptosis in Alzheimer's disease models by targeting KEAP1[J]. Acta Pharmacologica Sinica, 2024.
Authors:  Peng-xi Deng;  Marta Silva;  Na Yang;  Qing Wang;  Xin Meng; et al.
Favorite | TC[WOS]:1 TC[Scopus]:0  IF:6.9/7.6 | Submit date：2024/08/31
Alzheimer's Disease  Artemisinin  Ferroptosis  Keap1  Nrf2  Hippocampus  
Rasagiline Exerts Neuroprotection towards Oxygen–Glucose-Deprivation/Reoxygenation-Induced GAPDH-Mediated Cell Death by Activating Akt/Nrf2 Signaling Journal article
Lecht, Shimon, Lahiani, Adi, Klazas, Michal, Naamneh, Majdi Saleem, Rubin, Limor, Dong, Jiayi, Zheng, Wenhua, Lazarovici, Philip. Rasagiline Exerts Neuroprotection towards Oxygen–Glucose-Deprivation/Reoxygenation-Induced GAPDH-Mediated Cell Death by Activating Akt/Nrf2 Signaling[J]. Biomedicines, 2024, 12(7), 1592.
Authors:  Lecht, Shimon;  Lahiani, Adi;  Klazas, Michal;  Naamneh, Majdi Saleem;  Rubin, Limor; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:3.9/4.1 | Submit date：2024/08/05
Akt  Cell Death  Gapdh  Ischemia-like Insult  Neuroprotection  Nrf2  Phosphorylation  Rasagiline  Ros  Pc 12 Neuronal Model  Α-synuclein  Parkinson’s Disease  Stroke  
Artemisinin protects against neural injury by targeting KEAP1 to inhibit ferroptosis in Alzheimer’s disease models Conference paper
Pengxi DENG, ZHENG WENHUA. Artemisinin protects against neural injury by targeting KEAP1 to inhibit ferroptosis in Alzheimer’s disease models[C], 2024.
Authors:  Pengxi DENG;  ZHENG WENHUA
Favorite |  | Submit date：2024/08/31
Artemisinin, Ferroptosis, Keap1, Nrf2, Alzheimer's Disease (Ad).  
Small molecule deoxynyboquinone triggers alkylation and ubiquitination of Keap1 at Cys489 on Kelch domain for Nrf2 activation and inflammatory therapy Journal article
Linghu, Ke-Gang, Zhang, Tian, Zhang, Guang-Tao, Lv, Peng, Zhang, Wenjun, Zhao, Guanding, Xiong, Shihong, Zhao, Mingming, Chen, Meiwan, HU YUANJIA, Zhang, Changsheng, Yu, Hua. Small molecule deoxynyboquinone triggers alkylation and ubiquitination of Keap1 at Cys489 on Kelch domain for Nrf2 activation and inflammatory therapy[J]. Journal of Pharmaceutical Analysis, 2024, 14(3), 401-415.
Authors:  Linghu, Ke-Gang;  Zhang, Tian;  Zhang, Guang-Tao;  Lv, Peng;  Zhang, Wenjun; et al.
Favorite | TC[WOS]:7 TC[Scopus]:9  IF:6.1/6.8 | Submit date：2024/01/02
Deoxynyboquinone  Anti-inflammation  Target  Keap1/nrf2  Alkylation  Ubiquitination  
Germacrane-type sesquiterpenoids from the flowers of Chrysanthemum indicum with hepatoprotective activity Journal article
Liu, Yu, Zhou, Fei, Shu, Hongzhen, Lin, Ligen, Zhang, Qingwen. Germacrane-type sesquiterpenoids from the flowers of Chrysanthemum indicum with hepatoprotective activity[J]. Food and Chemical Toxicology, 2023, 177, 113850.
Authors:  Liu, Yu;  Zhou, Fei;  Shu, Hongzhen;  Lin, Ligen;  Zhang, Qingwen
Favorite | TC[WOS]:1 TC[Scopus]:2  IF:3.9/4.5 | Submit date：2023/08/03
Chrysanthemum Indicum  Germacrane-type Sesquiterpenoids  Hepatoprotection  Kelch Domain Of Keap1  Nrf2  
Resveratrol regulates inflammation and improves oxidative stress via Nrf2 signaling pathway: Therapeutic and biotechnological prospects Journal article
Shahcheraghi,Seyed Hossein, Salemi,Fateme, Small,Shlomo, Syed,Suliman, Salari,Farzam, Alam,Waqas, Cheang,Wai San, Saso,Luciano, Khan,Haroon. Resveratrol regulates inflammation and improves oxidative stress via Nrf2 signaling pathway: Therapeutic and biotechnological prospects[J]. Phytotherapy Research, 2023, 37(4), 1590-1605.
Authors:  Shahcheraghi,Seyed Hossein;  Salemi,Fateme;  Small,Shlomo;  Syed,Suliman;  Salari,Farzam; et al.
Favorite | TC[WOS]:40 TC[Scopus]:41  IF:6.1/7.0 | Submit date：2023/08/03
Biotechnological Prospects  Nrf2  Oxidative Stress  Resveratrol  Therapeutic Status  
Molecular integrative study on interaction domains of nuclear factor erythroid 2-related factor 2 with sirtuin 6 Journal article
Fu,Wanmeng, Xiao,Zhengpan, Chen,Yibo, Pei,Jinli, Sun,Yan, Zhang,Zhuandan, Wu,Hao, Pei,Yechun, Wei,Shuangshuang, Wang,Yuerong, Wang,Dayong. Molecular integrative study on interaction domains of nuclear factor erythroid 2-related factor 2 with sirtuin 6[J]. Biochimie, 2023, 211, 68-77.
Authors:  Fu,Wanmeng;  Xiao,Zhengpan;  Chen,Yibo;  Pei,Jinli;  Sun,Yan; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:3.3/3.5 | Submit date：2023/08/03
Antioxidant Genes  Interaction Domains  Neh1  Neh3  Nrf2  Sirt6