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Anti-inflammatory bicyclic polyprenylated acylphloroglucinols with diverse architectures including an unprecedented 6/6/6 tricyclic core from Garcinia yunnanensis Journal article
Hu, Xin Yue, Luo, Hui Juan, Wei, Xin, Wang, Yu Zhuo, Ye, Yan Song, Wan, Shi Jie, Zheng, Dan, Zhou, Yu, Xu, Hong Xi, Li, Xing Ren, Lin, Li Gen, Xu, Gang. Anti-inflammatory bicyclic polyprenylated acylphloroglucinols with diverse architectures including an unprecedented 6/6/6 tricyclic core from Garcinia yunnanensis[J]. Bioorganic Chemistry, 2024, 153, 107864.
Authors:  Hu, Xin Yue;  Luo, Hui Juan;  Wei, Xin;  Wang, Yu Zhuo;  Ye, Yan Song; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.5/4.7 | Submit date：2024/11/05
1l-1β  Anti-inflammatory Activity  Bpap  Garcinia Yunnanensis  Nlrp3  
Discovery of natural product derivative triptolidiol as a direct NLRP3 inhibitor by reducing K63-specific ubiquitination Journal article
Ding Moyu, Ning Chengqing, Chen Shaoru, Yin Haoran, Xu Jing, WANG YING. Discovery of natural product derivative triptolidiol as a direct NLRP3 inhibitor by reducing K63-specific ubiquitination[J]. doi: 10.1111/bph.17320, 2024, 181(22), 1–18.
Authors:  Ding Moyu;  Ning Chengqing;  Chen Shaoru;  Yin Haoran;  Xu Jing; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:6.8/7.4 | Submit date：2024/10/06
Immunosuppressive Activity  Inflammasome-driven Disease  K63-linked Ubiquitination,  Nlrp3  Triptolide Derivative  Triptolidiol  
Exploring the anti-inflammatory ingredients and potential of golden buckwheat (Fagopyrum dibotrys) on the TLR4/NLRP3 pathway in acute lung injury Journal article
Hu, Yingfan, Liu, Xiaomin, Song, Yu, Zhang, Yan, Li, Wei, Zhang, Lele, Wang, Anqi, Su, Qian, Yang, Zhiyong, Zou, Liang. Exploring the anti-inflammatory ingredients and potential of golden buckwheat (Fagopyrum dibotrys) on the TLR4/NLRP3 pathway in acute lung injury[J]. Food Science and Nutrition, 2024.
Authors:  Hu, Yingfan;  Liu, Xiaomin;  Song, Yu;  Zhang, Yan;  Li, Wei; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:3.5/4.2 | Submit date：2024/05/16
Acute Lung Injury  Anti-inflammatory  Fagopyrum Dibotrys  Golden Buckwheat  Tlr4/nlrp3  
Upregulation of Nrf2 signaling: A key molecular mechanism of Baicalin's neuroprotective action against diabetes-induced cognitive impairment Journal article
Zheng, Yanfang, Wang, Chenxiang, Liu, Wenjing, Chen, Jiaying, Sun, Yibin, Chang, Dennis, Wang, Huan, Xu, Wen, Lu, Jin Jian, Zhou, Xian, Huang, Mingqing. Upregulation of Nrf2 signaling: A key molecular mechanism of Baicalin's neuroprotective action against diabetes-induced cognitive impairment[J]. Biomedicine and Pharmacotherapy, 2024, 174, 116579.
Authors:  Zheng, Yanfang;  Wang, Chenxiang;  Liu, Wenjing;  Chen, Jiaying;  Sun, Yibin; et al.
Favorite | TC[WOS]:3 TC[Scopus]:4  IF:6.9/6.8 | Submit date：2024/05/16
Baicalin  Diabetes-associated Cognitive Deficits  Keap1-nrf2  Neuroinflammation  Nlrp3 Inflammasome  Oxidative Stress  
Quercetin as a promising intervention for rat osteoarthritis by decreasing M1-polarized macrophages via blocking the TRPV1-mediated P2X7/NLRP3 signaling pathway Journal article
Li, Wenjun, He, Hebei, Du, Min, Gao, Mu, Sun, Qijie, Wang, Yeyang, Lu, Hanyu, Ou, Shuanji, Xia, Changliang, Xu, Changpeng, Zhao, Qi, Sun, Hongtao. Quercetin as a promising intervention for rat osteoarthritis by decreasing M1-polarized macrophages via blocking the TRPV1-mediated P2X7/NLRP3 signaling pathway[J]. Phytotherapy Research, 2024, 38(4), 1990-2006.
Authors:  Li, Wenjun;  He, Hebei;  Du, Min;  Gao, Mu;  Sun, Qijie; et al.
Favorite | TC[WOS]:4 TC[Scopus]:5  IF:6.1/7.0 | Submit date：2024/11/05
M1 Macrophage Polarization  Nlrp3  Osteoarthritis  P2x7  Quercetin  Trpv1  
Quercetin as a promising intervention for rat osteoarthritis by decreasing M1‐polarized macrophages via blocking the TRPV1‐mediated P2X7/NLRP3 signaling pathway Journal article
Li Wenjun, He Hebei, Du Min, Gao Mu, Sun Qijie, Wang Yeyang, Lu Hanyu, Ou Shuanji, Xin Changliang, Xu Changpeng, Zhao Qi, Sun Hongtao. Quercetin as a promising intervention for rat osteoarthritis by decreasing M1‐polarized macrophages via blocking the TRPV1‐mediated P2X7/NLRP3 signaling pathway[J]. Phytotherapy research, 2024, 38(4), 1990-2006.
Authors:  Li Wenjun;  He Hebei;  Du Min;  Gao Mu;  Sun Qijie; et al.
Adobe PDF | Favorite | TC[WOS]:4 TC[Scopus]:5  IF:6.1/7.0 | Submit date：2024/03/18
M1 Macrophage Polarization  Nlrp3  Osteoarthritis  P2x7  Quercetin  Trpv1  
Heme oxygenase 1-mediated ferroptosis in Kupffer cells initiates liver injury during heat stroke Journal article
Li, Ru, Wei, Riqing, Liu, Chenxin, Zhang, Keying, He, Sixiao, Liu, Zhifeng, Huang, Junhao, Tang, Youyong, An, Qiyuan, Lin, Ligen, Gan, Lishe, Zhao, Liying, Zou, Xiaoming, Wang, Fudi, Ping, Yuan, Ma, Qiang. Heme oxygenase 1-mediated ferroptosis in Kupffer cells initiates liver injury during heat stroke[J]. Acta Pharmaceutica Sinica B, 2024.
Authors:  Li, Ru;  Wei, Riqing;  Liu, Chenxin;  Zhang, Keying;  He, Sixiao; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:14.7/14.1 | Submit date：2024/07/04
Early Growth Response Factor 1  Ferroptosis  Heat Stroke  Heme Oxygenase 1  Kupffer Cells  Liver Injury  Nlrp3  Phosphatidylinositol 4-kinase Beta  
Limonoids from the roots of Melia azedarach and their anti-inflammatory activity Journal article
Song, Min, Luo, Hui Juan, Li, Zi Wei, Qiu, Ling, Zhao, Yu Xin, He, Cheng Wei, Zhang, Xiao Qi, Ye, Wen Cai, Lin, Li Gen, Zhang, Qing Wen. Limonoids from the roots of Melia azedarach and their anti-inflammatory activity[J]. Phytochemistry, 2023, 216, 113869.
Authors:  Song, Min;  Luo, Hui Juan;  Li, Zi Wei;  Qiu, Ling;  Zhao, Yu Xin; et al.
Favorite | TC[WOS]:2 TC[Scopus]:3  IF:3.2/3.4 | Submit date：2024/01/02
1l-1β  Anti-inflammatory Activity  Limonoids  MeL.a Azedarach L.  Nlrp3  
TREM2 Deficiency Aggravates NLRP3 Inflammasome Activation and Pyroptosis in MPTP-Induced Parkinson’s Disease Mice and LPS-Induced BV2 Cells Journal article
Huang, Peiting, Zhang, Zhanyu, Zhang, Piao, Feng, Jiezhu, Xie, Jianwei, Zheng, Yinjuan, Liang, Xiaomei, Zhu, Baoyu, Chen, Zhenzhen, Feng, Shujun, Wang, Lijuan, Lu, Jiahong, Liu, Yawei, Zhang, Yuhu. TREM2 Deficiency Aggravates NLRP3 Inflammasome Activation and Pyroptosis in MPTP-Induced Parkinson’s Disease Mice and LPS-Induced BV2 Cells[J]. Molecular Neurobiology, 2023, 61(5), 2590-2605.
Authors:  Huang, Peiting;  Zhang, Zhanyu;  Zhang, Piao;  Feng, Jiezhu;  Xie, Jianwei; et al.
Favorite | TC[WOS]:10 TC[Scopus]:12  IF:4.6/4.7 | Submit date：2024/02/22
Inflammasome  Nlrp3  Parkinson’s Disease  Pyroptosis  Trem2  
Ginsenoside Rk2, a dehydroprotopanaxadiol saponin, alleviates alcoholic liver disease via regulating NLRP3 and NLRP6 inflammasome signaling pathways in mice Journal article
Jian Zou, Rujie Yang, Ruibing Feng, Jiayue Liu, Jian Bo Wan. Ginsenoside Rk2, a dehydroprotopanaxadiol saponin, alleviates alcoholic liver disease via regulating NLRP3 and NLRP6 inflammasome signaling pathways in mice[J]. Journal of Pharmaceutical Analysis, 2023, 13(9), 999-1012.
Authors:  Jian Zou;  Rujie Yang;  Ruibing Feng;  Jiayue Liu;  Jian Bo Wan
Favorite | TC[WOS]:6 TC[Scopus]:6  IF:6.1/6.8 | Submit date：2023/10/10
Alcoholic Liver Disease  Ginsenoside Rk2  Intestinal Barrier Dysfunction  Nlrp3 Inflammasome  Nlrp6 Inflammasome