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P-tau217 correlates with neurodegeneration in Alzheimer's disease, and targeting p-tau217 with immunotherapy ameliorates murine tauopathy Journal article
Zhang, Denghong, Zhang, Wei, Ming, Chen, Gao, Xuheng, Yuan, Huilong, Lin, Xiaojie, Mao, Xinru, Wang, Chunping, Guo, Xiaoyi, Du, Ying, Shao, Lin, Yang, Renzhi, Lin, Zhihao, Wu, Xilin, Huang, Timothy Y., Wang, Zhanxiang, Zhang, Yun wu, Xu, Huaxi, Zhao, Yingjun. P-tau217 correlates with neurodegeneration in Alzheimer's disease, and targeting p-tau217 with immunotherapy ameliorates murine tauopathy[J]. Neuron, 2024, 112(10), 1676-1693.e12.
Authors:  Zhang, Denghong;  Zhang, Wei;  Ming, Chen;  Gao, Xuheng;  Yuan, Huilong; et al.
Favorite | TC[WOS]:9 TC[Scopus]:9  IF:14.7/16.9 | Submit date：2024/05/16
Alzheimer's Disease  Cell Death  Cognitive Impairment  Immunotherapy  Motor Dysfunction  Neurodegeneration  Neurodegenerative Disease  P-tau217  Tau  Tauopathy  
A Three-Way Combinatorial CRISPR Screen for Analyzing Interactions among Druggable Targets Journal article
Zhou,Peng, Chan,Becky K.C., Wan,Yuk Kei, Yuen,Chaya T.L., Choi,Gigi C.G., Li,Xinran, Tong,Cindy S.W., Zhong,Sophia S.W., Sun,Jieran, Bao,Yufan, Mak,Silvia Y.L., Chow,Maggie Z.Y., Khaw,Jien Vei, Leung,Suet Yi, Zheng,Zongli, Cheung,Lydia W.T., Tan,Kaeling, Wong,Koon Ho, Chan,H. Y.Edwin, Wong,Alan S.L.. A Three-Way Combinatorial CRISPR Screen for Analyzing Interactions among Druggable Targets[J]. Cell Reports, 2020, 32(6), 108020.
Authors:  Zhou,Peng;  Chan,Becky K.C.;  Wan,Yuk Kei;  Yuen,Chaya T.L.;  Choi,Gigi C.G.; et al.
Favorite | TC[WOS]:26 TC[Scopus]:27  IF:7.5/8.5 | Submit date：2021/03/04
Cancer  Combigem  Combination Therapy  Combinatorial Genetics  Crispr  Drug Interaction  Genetic Interaction  High-throughput Screening  Neurodegeneration  Parkinson's Disease  
TDP-1/TDP-43 potentiates human α-Synuclein (HASN) neurodegeneration in Caenorhabditis elegans Journal article
Shen,Linjing, Wang,Changliang, Chen,Liang, Leung,Ka Lai, Lo,Esther, Lakso,Merja, Wong,Garry. TDP-1/TDP-43 potentiates human α-Synuclein (HASN) neurodegeneration in Caenorhabditis elegans[J]. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2020, 1866(10), 165876.
Authors:  Shen,Linjing;  Wang,Changliang;  Chen,Liang;  Leung,Ka Lai;  Lo,Esther; et al.
Favorite | TC[WOS]:19 TC[Scopus]:17  IF:4.2/5.5 | Submit date：2021/03/02
Α-synuclein  Tdp-1/tdp-43  Tdp-43  Parkinson's Disease  Lewy Body Dementia  C. Elegans  Neurodegeneration  
A reciprocal relationship between reactive oxygen species and mitochondrial dynamics in neurodegeneration Journal article
Hung, Clara Hiu-Ling, Cheng, Sally Shuk-Yee, Cheung, Yuen-Ting, Wuwongse, Suthicha, Zhang, Natalie Qishan, Ho, Yuen-Shan, Lee, Simon Ming-Yuen, Chang, Raymond Chuen-Chung. A reciprocal relationship between reactive oxygen species and mitochondrial dynamics in neurodegeneration[J]. REDOX BIOLOGY, 2018, 14, 7-19.
Authors:  Hung, Clara Hiu-Ling;  Cheng, Sally Shuk-Yee;  Cheung, Yuen-Ting;  Wuwongse, Suthicha;  Zhang, Natalie Qishan; et al.
Favorite | TC[WOS]:113 TC[Scopus]:115  IF:10.7/11.7 | Submit date：2018/10/30
Alzheimer's Disease  Beta-amyloid  Mitochondria  Fission And Fusion  Drp-1  Neurodegeneration  
Research progress on effects of indirubin and its structurally similar compounds on anticancer and neuroprotection Journal article
Wang,Ying, Sa,Fei, Chan,Yuet Wa, Lee,Ming Yuen. Research progress on effects of indirubin and its structurally similar compounds on anticancer and neuroprotection[J]. Chinese Traditional and Herbal Drugs, 2014, 45(16), 2404-2411.
Authors:  Wang,Ying;  Sa,Fei;  Chan,Yuet Wa;  Lee,Ming Yuen
Favorite | TC[Scopus]:3 | Submit date：2021/03/02
Anticancer  Cyclin-dependent Kinases  Glycogen Synthase Kinase-3  Indirubin  Neurodegeneration Disease  
Zebrafish as a new model for drug metabolism and high content screen of natural product Conference paper
Lee, SMY, Hoi, PM, Yan, R, Wang, YQ, Han, YF, Chu, IK. Zebrafish as a new model for drug metabolism and high content screen of natural product[C], 2014.
Authors:  Lee, SMY;  Hoi, PM;  Yan, R;  Wang, YQ;  Han, YF; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0 | Submit date：2020/03/26
Drug Metabolism  Chinese Medicine  Zebrafish  Neurodegeneration  Vascular Disease  
Zebrafish as a new model for drug metabolism and high content screen of natural product Journal article
Lee, SMY, Hoi, PM, Yan, R, Wang, YQ, Han, YF, Chu, IK. Zebrafish as a new model for drug metabolism and high content screen of natural product[J]. PLANTA MEDICA, 2014, 80(16).
Authors:  Lee, SMY;  Hoi, PM;  Yan, R;  Wang, YQ;  Han, YF; et al.
Favorite | TC[WOS]:0   IF:2.1/2.8 | Submit date：2020/03/26
Neurodegeneration  Chinese Medicine  Zebrafish  Drug Metabolism  Vascular Disease  
SKN-1/Nrf2 inhibits dopamine neuron degeneration in a Caenorhabditis elegans model of methylmercury toxicity Journal article
VanDuyn N., Settivari R., Wong G., Nass R.. SKN-1/Nrf2 inhibits dopamine neuron degeneration in a Caenorhabditis elegans model of methylmercury toxicity[J]. Toxicological Sciences, 2010, 118(2), 613-624.
Authors:  VanDuyn N.;  Settivari R.;  Wong G.;  Nass R.
Favorite | TC[WOS]:75 TC[Scopus]:90 | Submit date：2018/12/18
C. Elegans  Dopamine Neurodegeneration  Genetics  Methylmercury  Nematode  Nrf2  Oxidative Stress  Parkinson's Disease  Skn-1  
Global microRNA expression profiling of caenorhabditis elegans Parkinson's disease models Journal article
Asikainen S., Rudgalvyte M., Heikkinen L., Louhiranta K., Lakso M., Wong G., Nass R.. Global microRNA expression profiling of caenorhabditis elegans Parkinson's disease models[J]. Journal of Molecular Neuroscience, 2010, 41(1), 210-218.
Authors:  Asikainen S.;  Rudgalvyte M.;  Heikkinen L.;  Louhiranta K.;  Lakso M.; et al.
Favorite | TC[WOS]:85 TC[Scopus]:85 | Submit date：2018/12/18
Caenorhabditis Elegans  Microarray  Microrna  Neurodegeneration  Parkinson's Disease  Qrt-pcr