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A small molecule cryptotanshinone induces non-enzymatic NQO1-dependent necrosis in cancer cells through the JNK1/2/Iron/PARP/calcium pathway
Journal article
Hou, Ying, Zhong, Bingling, Zhao, Lin, Wang, Heng, Zhu, Yanyan, Wang, Xianzhe, Zheng, Haoyi, Yu, Jie, Liu, Guokai, Wang, Xin, Martin-Garcia, Jose M., Chen, Xiuping. A small molecule cryptotanshinone induces non-enzymatic NQO1-dependent necrosis in cancer cells through the JNK1/2/Iron/PARP/calcium pathway[J]. Acta Pharmaceutica Sinica B, 2024.
Authors:
Hou, Ying
;
Zhong, Bingling
;
Zhao, Lin
;
Wang, Heng
;
Zhu, Yanyan
; et al.
Favorite
|
TC[Scopus]:
0
IF:
14.7
/
14.1
|
Submit date:2025/01/22
Nqo1
Cryptotanshinone
Iron
Ferroptosis
Nad++++ Depletion
Calcium
Targeted Therapy
Cancer
SP600125, a selective JNK inhibitor, is a potent inhibitor of NAD(P)H: quinone oxidoreductase 1 (NQO1)
Journal article
Zhong, Bing Ling, Zhang, Yi Fei, Zheng, Hao Yi, Chen, Qiang, Lu, Hua Dong, Chen, Xiu Ping. SP600125, a selective JNK inhibitor, is a potent inhibitor of NAD(P)H: quinone oxidoreductase 1 (NQO1)[J]. Acta Pharmacologica Sinica, 2024.
Authors:
Zhong, Bing Ling
;
Zhang, Yi Fei
;
Zheng, Hao Yi
;
Chen, Qiang
;
Lu, Hua Dong
; et al.
Favorite
|
TC[WOS]:
0
TC[Scopus]:
1
IF:
6.9
/
7.6
|
Submit date:2024/12/05
Jnk
Nqo1
Sp600125
Fighting drug-resistant lung cancer by induction of NAD(P)H:quinone oxidoreductase 1 (NQO1)-mediated ferroptosis
Journal article
Yu,Jie, Zhong,Bingling, Zhao,Lin, Hou,Ying, Ai,Nana, Lu,Jin Jian, Ge,Wei, Chen,Xiuping. Fighting drug-resistant lung cancer by induction of NAD(P)H:quinone oxidoreductase 1 (NQO1)-mediated ferroptosis[J]. Drug Resistance Updates, 2023, 70, 100977.
Authors:
Yu,Jie
;
Zhong,Bingling
;
Zhao,Lin
;
Hou,Ying
;
Ai,Nana
; et al.
Favorite
|
TC[WOS]:
38
TC[Scopus]:
37
IF:
15.8
/
18.1
|
Submit date:2023/08/03
Drug-resistance
Ferroptosis
Lung Cancer
Mam
Nqo1
The Anticancer Effect of Napabucasin (BBI608), a Natural Naphthoquinone
Journal article
Shao, Zeyang, Wang, Heng, Ren, Haiyan, Sun, Yinxiang, Chen, Xiuping. The Anticancer Effect of Napabucasin (BBI608), a Natural Naphthoquinone[J]. Molecules, 2023, 28(15).
Authors:
Shao, Zeyang
;
Wang, Heng
;
Ren, Haiyan
;
Sun, Yinxiang
;
Chen, Xiuping
Favorite
|
TC[WOS]:
13
TC[Scopus]:
15
IF:
4.2
/
4.6
|
Submit date:2024/01/10
cancer
napabucasin
NQO1
STAT3
The Anticancer Effect of Napabucasin (BBI608), a Natural Naphthoquinone
Journal article
Zeyang Ahao, Heng Wang, Haiyan Ren, Yinxiang Sun, Xiuping Chen. The Anticancer Effect of Napabucasin (BBI608), a Natural Naphthoquinone[J]. Molecules, 2023, 28(15), 5678.
Authors:
Zeyang Ahao
;
Heng Wang
;
Haiyan Ren
;
Yinxiang Sun
;
Xiuping Chen
Adobe PDF
|
Favorite
|
TC[WOS]:
13
TC[Scopus]:
15
IF:
4.2
/
4.6
|
Submit date:2023/08/17
Cancer
Napabucasin
Nqo1
Stat3
Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) inhibitors Necrostatin-1 (Nec-1) and 7-Cl-O-Nec-1 (Nec-1s) are potent inhibitors of NAD(P)H: Quinone oxidoreductase 1 (NQO1)
Journal article
Yu, Jie, Zhong, Bingling, Zhao, Lin, Hou, Ying, Wang, Xianzhe, Chen, Xiuping. Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) inhibitors Necrostatin-1 (Nec-1) and 7-Cl-O-Nec-1 (Nec-1s) are potent inhibitors of NAD(P)H: Quinone oxidoreductase 1 (NQO1)[J]. FREE RADICAL BIOLOGY AND MEDICINE, 2021, 173, 64-69.
Authors:
Yu, Jie
;
Zhong, Bingling
;
Zhao, Lin
;
Hou, Ying
;
Wang, Xianzhe
; et al.
Favorite
|
TC[WOS]:
7
TC[Scopus]:
8
IF:
7.1
/
7.9
|
Submit date:2021/12/08
Nec-1
Nec-1s
Nqo1
Ripk1
A novel strategy for glioblastoma treatment by induction of noptosis, an NQO1-dependent necrosis
Journal article
Zhong, Bingling, Yu, Jie, Hou, Ying, Ai, Nana, Ge, Wei, Lu, Jin Jian, Chen, Xiuping. A novel strategy for glioblastoma treatment by induction of noptosis, an NQO1-dependent necrosis[J]. Free Radical Biology and Medicine, 2021, 166, 104-115.
Authors:
Zhong, Bingling
;
Yu, Jie
;
Hou, Ying
;
Ai, Nana
;
Ge, Wei
; et al.
Favorite
|
TC[WOS]:
14
TC[Scopus]:
14
IF:
7.1
/
7.9
|
Submit date:2021/09/17
Cell Death
Danshen
Noptosis
Nqo1
2-Methoxy-6-acetyl-7-methyljuglone (MAM) induced programmed necrosis in glioblastoma by targeting NAD(P)H: Quinone oxidoreductase 1 (NQO1)
Journal article
Yu, Jie, Zhong, Bingling, Jin, Long, Hou, Ying, Ai, Nana, Ge, Wei, Li, Luoxiang, Liu, Shuqin, Lu, Jin Jian, Chen, Xiuping. 2-Methoxy-6-acetyl-7-methyljuglone (MAM) induced programmed necrosis in glioblastoma by targeting NAD(P)H: Quinone oxidoreductase 1 (NQO1)[J]. Free Radical Biology and Medicine, 2020, 152, 336-347.
Authors:
Yu, Jie
;
Zhong, Bingling
;
Jin, Long
;
Hou, Ying
;
Ai, Nana
; et al.
Favorite
|
TC[WOS]:
26
TC[Scopus]:
29
IF:
7.1
/
7.9
|
Submit date:2021/09/17
Mam
Glioblastoma
Programmed Necrosis
Nqo1
2-甲氧基-6-乙酰基-7-甲基胡桃酮的应用
Patent
专利类型: 发明专利 Invention, 专利号: CN110772503A, 申请日期: 2019-10-11,
Authors:
陈修平
;
葛伟
;
余洁
;
钟冰玲
Favorite
|
|
Submit date:2022/05/21
Nqo1
NQO1 dependent non-canonical necroptosis mediated by ROS and RIP1/RIP3 in parallel in glioma cancer cells
Conference paper
Yu, J., Wu, X.X., Wang, C.X., Gao, H.W., Sun, W., Lu, J., Chen, X. P.. NQO1 dependent non-canonical necroptosis mediated by ROS and RIP1/RIP3 in parallel in glioma cancer cells[C], 2018.
Authors:
Yu, J.
;
Wu, X.X.
;
Wang, C.X.
;
Gao, H.W.
;
Sun, W.
; et al.
Favorite
|
|
Submit date:2022/08/26
MAM
glioblastomas
non-canonical necroptosis
NQO1