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Lycorine protects motor neurons against TDP-43 proteinopathy-induced degeneration in cross-species models with amyotrophic lateral sclerosis Journal article
Wen, Jing, Li, Yunhao, Qin, Yanzhu, Yan, Lingli, Zhang, Ke, Li, Ang, Wang, Ziying, Yu, Feng, Lai, Jianheng, Yang, Wei, Liu, Yong U., Qin, Dajiang, Su, Huanxing. Lycorine protects motor neurons against TDP-43 proteinopathy-induced degeneration in cross-species models with amyotrophic lateral sclerosis[J]. Pharmacological Research, 2024, 210, 107518.
Authors:  Wen, Jing;  Li, Yunhao;  Qin, Yanzhu;  Yan, Lingli;  Zhang, Ke; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:9.1/9.0 | Submit date：2024/12/05
Als  Tdp-43 Proteinopathy  Lycorine  Ups  Motor Neurons  Piceatanno l (Pubchem Cid: 667639)  Tubeimoside i (Pubchem Cid: 51346132)  Lycorine (Pubchem Cid: 72378)  Isoginkgetin (Pubchem Cid: 5318569)  Cycloheximide (Pubchem Cid: 6197)  Mg-132 (Pubchem Cid: 462382)  Bortezomib (Pubchem Cid: 387447)  Chloroquine (Pubchem Cid: 2719)  Bafilomycin A1 (Pubchem Cid: 6436223)  H89 (Pubchem Cid: 449241)  
Uncover the anticancer potential of lycorine Journal article
Zhang, Yan Ming, Li, Ting, Xu, Chun Cao, Qian, Jia Yu, Guo, Hongwei, Zhang, Xiaolei, Zhan, Zha Jun, Lu, Jin Jian. Uncover the anticancer potential of lycorine[J]. Chinese Medicine (United Kingdom), 2024, 19(1), 121.
Authors:  Zhang, Yan Ming;  Li, Ting;  Xu, Chun Cao;  Qian, Jia Yu;  Guo, Hongwei; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2 | Submit date：2024/10/10
Anticancer Mechanism  Lycorine  Lycorine Hydrochloride  Pharmacokinetics  Target  
Lycorine promotes IDH1 acetylation to induce mitochondrial dynamics imbalance in colorectal cancer cells Journal article
Fang-Fang Zhuo, Ling Li, Ting-Ting Liu, Xiao-Min Liang, Zhuo Yang, Yong-Zhe Zheng, Qian-Wei Luo, Jia-Hong Lu, Dan Liu, Ke-Wu Zeng, Peng-Fei Tu. Lycorine promotes IDH1 acetylation to induce mitochondrial dynamics imbalance in colorectal cancer cells[J]. Cancer Letters, 2023, 573, 216364.
Authors:  Fang-Fang Zhuo;  Ling Li;  Ting-Ting Liu;  Xiao-Min Liang;  Zhuo Yang; et al.
Favorite | TC[WOS]:11 TC[Scopus]:13  IF:9.1/8.3 | Submit date：2023/09/22
Colorectal Cancer  Isocitrate Dehydrogenase (Idh)  Lycorine  Mitochondrial Dynamics  Oxidative Stress  Sirtuin 1  
Lycorine, a natural alkaloid, promotes the degradation of alpha-synuclein via PKA-mediated UPS activation in transgenic Parkinson's disease models Journal article
Zhu, Qi, Zhuang, Xu xu, Chen, Jia yue, Yuan, Ning ning, Chen, Yan, Cai, Cui zan, Tan, Jie qiong, Su, Huan xing, Lu, Jia hong. Lycorine, a natural alkaloid, promotes the degradation of alpha-synuclein via PKA-mediated UPS activation in transgenic Parkinson's disease models[J]. Phytomedicine, 2021, 87, 153578.
Authors:  Zhu, Qi;  Zhuang, Xu xu;  Chen, Jia yue;  Yuan, Ning ning;  Chen, Yan; et al.
Favorite | TC[WOS]:19 TC[Scopus]:20  IF:6.7/6.2 | Submit date：2021/12/08
Camp/pka Pathway  Lycorine  Parkinson's Disease  Ubiquitin-proteasome System  Α-synuclein