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Divergence of anti-angiogenic activity and hepatotoxicity of different stereoisomers of itraconazole Journal article
Joong Sup Shim, Ruo-Jing Li, Namandje N. Bumpus, Sarah A. Head, Kalyan Kumar, Eun Ju Yang, Junfang Lv, Wei Shi, Jun O. Liu. Divergence of anti-angiogenic activity and hepatotoxicity of different stereoisomers of itraconazole[J]. Clinical Cancer Research, 2016, 22(11), 2709-2720.
Authors:  Joong Sup Shim;  Ruo-Jing Li;  Namandje N. Bumpus;  Sarah A. Head;  Kalyan Kumar; et al.
Favorite | TC[WOS]:12 TC[Scopus]:12  IF:10.0/11.1 | Submit date：2019/01/24
Itraconazole  Stereoisomers  Drug Repositioning  Angiogenesis  Hepatotoxicity  
Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells Journal article
Head S.A., Shi W., Zhao L., Gorshkov K., Pasunooti K., Chen Y., Deng Z., Li R.-J., Shim J.S., Tan W., Hartung T., Zhang J., Zhao Y., Colombini M., Liu J.O.. Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells[J]. Proceedings of the National Academy of Sciences of the United States of America, 2015, 112(52), E7276.
Authors:  Head S.A.;  Shi W.;  Zhao L.;  Gorshkov K.;  Pasunooti K.; et al.
Favorite | TC[WOS]:83 TC[Scopus]:88 | Submit date：2018/10/30
Angiogenesis  Itraconazole  Metabolism  Mitochondria  Vdac1  
The antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells Journal article
Sarah A. Head, Wei Shi, Liang Zhao, Kirill Gorshkov, Kalyan Pasunooti, Yue Chen, Zhiyou Deng, Ruo-jing Li, Joong Sup Shim, Wenzhi Tan, Thomas Hartung, Jin Zhang, Yingming Zhao, Marco Colombini, Jun O. Liu. The antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015, 112(52), E7276-E7285.
Authors:  Sarah A. Head;  Wei Shi;  Liang Zhao;  Kirill Gorshkov;  Kalyan Pasunooti; et al.
Favorite | TC[WOS]:83 TC[Scopus]:88  IF:9.4/10.8 | Submit date：2019/01/24
Angiogenesis  Mitochondria  Metabolism  Itraconazole  Vdac1